Publications
Dorrazehi, Gol Mohammad ; Winkle, Matthias ; Desmet, Martin ; Stroobant, Vincent ; Tanriver, Gamze ; Degand, Hervé ; Evrard, Damien ; Desguin, Benoît ; Morsomme, Pierre ; Biboy, Jacob ; Gray, Joe ; Mitusińska, Karolina ; Góra, Artur ; Vollmer, Waldemar ; Soumillion, Patrice. PBP-A, a cyanobacterial DD-peptidase with high specificity for amidated muropeptides, exhibits pH-dependent promiscuous activity harmful to Escherichia coli.. In: Scientific reports, Vol. 14, no. 1, p. 13999 (2024). doi:10.1038/s41598-024-64806-x (Accepté/Sous presse).
Urdiain-Arraiza, Julian ; Desguin, Benoît. Versatile capillary electrophoresis method for the direct chiral separation of aliphatic and aromatic α-hydroxy acids, β-hydroxy acids and polyhydroxy acids using vancomycin as chiral selector. In: Journal of Chromatography A, Vol. 1715, no. 464611, p. 1-13 (2024). doi:10.1016/j.chroma.2023.464611.
Gatreddi, Santhosh ; Urdiain-Arraiza, Julian ; Desguin, Benoît ; Hausinger, Robert P ; Hu, Jian. Structural and mutational characterization of a malate racemase from the LarA superfamily.. In: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 36, no.2, p. 303-313 (2023). doi:10.1007/s10534-022-00372-x.
Rankin, Joel A ; Chatterjee, Shramana ; Tariq, Zia ; Lagishetty, Satyanarayana ; Desguin, Benoît ; Hu, Jian ; Hausinger, Robert P. The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.. In: Proceedings of the National academy of sciences of the United States of America, Vol. 118, no.39, p. e2106202118 (2021). doi:10.1073/pnas.2106202118.
Desguin, Benoît ; Urdiain-Arraiza, Julian ; Da Costa, Matthieu ; Fellner, Matthias ; Hu, Jian ; Hausinger, Robert P ; Desmet, Tom ; Hols, Pascal ; Soumillion, Patrice. Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.. In: Scientific reports, Vol. 10, no.1, p. 18123 (2020). doi:10.1038/s41598-020-74802-6.
Fellner, Matthias ; Rankin, Joel A ; Desguin, Benoît ; Hu, Jian ; Hausinger, Robert P. Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum.. In: Biochemistry, Vol. 57, no.38, p. 5513-5523 (2018). doi:10.1021/acs.biochem.8b00601.
Desguin, Benoît ; Fellner, Matthias ; Riant, Olivier ; Hu, Jian ; Hausinger, Robert ; Hols, Pascal ; Soumillion, Patrice. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.. In: Journal of Biological Chemistry, (2018). doi:10.1074/jbc.RA118.003741.
Rankin, Joel A ; Mauban, Robert C ; Fellner, Matthias ; Desguin, Benoît ; McCracken, John ; Hu, Jian ; Varganov, Sergey A ; Hausinger, Robert P. Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism.. In: Biochemistry, Vol. 57, no.23, p. 3244-3251 (2018). doi:10.1021/acs.biochem.8b00100.
Desguin, Benoit. Lactate Racemization and Beyond. In: Journal of Bacteriology & Parasitology, Vol. 09, no. 02 (2018) (2018). doi:10.4172/2155-9597.1000335.
Hausinger, Robert P ; Hu, Jian ; Desguin, Benoît. The nickel-pincer coenzyme of lactate racemase: A case study of uncovering cofactor structure and biosynthesis.. In: John P. Richard and Graham R. Moran (eds.), New Experimental Probes for Enzyme Specificity and Mechanism (Methods in Enzymology; 685), Academic Press: Massachusetts, 2023, p. 341-371. 9780443152764. doi:10.1016/bs.mie.2023.03.006.
Desguin, Benoît. LarC Cyclometallase. In: Robert A Scott, John Wiley & Sons, Encyclopedia of Inorganic and Bioinorganic Chemistry, 2020. 9781119951438. doi:10.1002/9781119951438.eibc2737.
Desguin, Benoît. Biosynthesis and functions of the Nickel-pincer nucleotide (NPN). Novel Enzymes 2023.
Desguin, Benoît. Biosynthesis and Functions of the Nickel-Pincer Nucleotide cofactor. NextGenBiocat 2022 .
Desguin, Benoît. Biosynthesis and functions of the nickel-pincer cofactor. BioTrans 2019 .
Desguin, Benoît. Biosynthesis and functions of the nickel-pincer cofactor. Biometals 2018 .
Desguin, Benoît. Biosynthesis and functions of the nickel-pincer cofactor. Novel Enzymes 2018 .
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