In her abstract, she reminds us that “The timing and pattern of rhythmic, stereotyped and coordinated muscle activities are controlled by specific neural cicuits, called central pattern generators. There are different types of CPGs that underlie different motor programs. CPGs controlling locomotion are located in the ventral spinal cord and consists in networks of interneurons that determine appropriate sequences of flexors/extensors activation during gait or running. The existence of the locomotor CPG has been demonstrated in the in vitro preparation of the isolated spinal cord by the possibility to induce a rhythm of fictive locomotion. Fictive locomotion corresponds to a characteristic response recorded from the spinal ventral roots that consists in the generation of rhythmically alternated locomotor cycles between specific pairs of ventral roots. Experimentally, it is possible to induce a fictive locomotion, and thus the activation of the locomotor CPG, using pharmacological or electrical protocols. In particular, the innovative electrical stimulating protocol FListim has proven to be very effective in evoking episodes of FL, since it can optimally activate the locomotor CPG at much lower intensities of stimulation than canonical electrical square pulses. In our work we have demonstrated how the activation or the modulation of the activity of the locomotor CPG, in turn, can have an effect on the frequency and amplitude of dorsal root discharges.”