The Cellular and Molecular Neuroscience division comprises eight research groups that use molecular and cell biology, biochemistry, pharmacology, transgenesis, imaging and electrophysiology to investigate the fundamental bases of development, physiology and pathologies of the nervous system.
Research interests include the characterization of mechanisms involved in neural differentiation, neuronal migration, axon guidance, synaptogenesis and synaptic plasticity, in neuronal, glial or muscular physiology related to physical activity, in the alterations of nervous activity in chronic pain, in the degeneration of neuronal, glial or muscle cells in the course of degenerative or metabolic disorders and in tumorigenesis in the central nervous system. In the long run, the aim of our research is to improve diagnosis and treatment of neurodevelopmental disorders, of neurodegenerative pathologies including Alzheimer’s disease, Parkinson’s disease and multiple sclerosis, and of neuromuscular diseases such as Duchenne muscular dystrophy and amyotrophic lateral sclerosis, glioblastomas and metabolic diseases related to sedentary lifestyle.
Research groups
- AGing And Dementia (AGAD) (PI: Pascal Kienlen-Campard)
- Neuroimmunology and CSF Neurochemistry (NCHM) (PI: Vincent Van Pesch)
- Mammalian Development & Cell Biology (MACE) (PI: Yves Jossin)
- Developmental neurobiology group (DENE) (PI: Fadel Tissir)
- Laboratory of Cell Physiology (FYCL) (PIs: Philippe Gailly, Roberta Gualdani, Nicolas Tajeddine)
- Neuropharmacology (NFAR) (PI: Emmanuel Hermans)
- Laboratory of Nutritional Psychiatry (NUPS) (PI: Sophie Leclercq)
- Physiology and molecular biology of exercise (PIs: Marc Francaux, Louise Deldicque)