Humans and other animals have a brain that has been shaped by evolution to process and integrate information from different sensory organs, each capturing different form of energies in the environment. How does this diversity of sensory information affect how people represent the world? Where in the brain are the different sensory information combined? How do we represent in our mind and brain something that we can see, hear, feel and smell ? Does the brain implement represention that go beyond the sensory experience we have of things?
The presence of these different sensory systems also paves the way for considerable flexibility by allowing perceptual, cognitive, or brain systems to supplement another following sensory deprivation. Part of our research is driven by the strong conviction that the study of sensory deprived individuals (blind, deaf, anosmic, Moebius) represents an excellent model to probe how the brain develops, maintains, and changes its functional tuning to adapt its interaction with the environment. What happens when one or more of these senses is lost or never developed? Research at the CPP-lab investigates the relationship between a brain that is intrinsically multisensory and how sensory deprivation influence these entangled sensory networks.
Sensory deprivation is also used to causally test the role of sensory experience in how we represent information in our mind. The goal is to establish which aspects of cognition and perception are fundamentally shaped by our sensory experience and which are abstracted from sensory experience and/or mostly relying on language. To do so, we are also developing studies in babies to understand how the mind and brain develop their functional architecture.
Our work relies on the respective advantages of a plurality of methods (Psychophysics, EEG/MEG, stereotactic-EEG, TMS, fMRI) to converge toward a comprehensive understanding of the mechanisms underlying crossmodal perception and plasticity. This coordinated approach has been successfully used to reveals fundamentals of how the mind and brain integrate and segregate sensory information in various populations and how the intrinsic multisensory scaffolding of brain networks constrains the expression of cross modal plasticity in sensory deprived people.
Team members
Principal Investigator
Postdoctoral researchers
PhD students
- Giraudet Eleonore
- Shazad Iqra
- Van Audenhaege Alice
- Azouri Marie-Ange
- Yang Ying
- Esposito Giulia
- Cerpelloni Filippo
- Barilari Marco
- Talwar Siddarth
- Xu Yufeng
Collaborations
- Prof. F. Lepore (U. Montreal): Hemianopsia + sensory deprivation.
- Prof. A. Bertone (McGill U.) and L. Mottron (UdM): Multisensory processing in autism.
- Profs D. Maurer, T. Lewis (McMaster U.) and Xiaoqing Gao (Zhejiang University, China). Multisensory reorganization in cataract-recovery patients.
- Prof. N. Weisz (U. Salzburg). MEG analyses.
- Prof. B. Rossion (U. Louvain). Frequency Tagging.
- Prof. Naima Deggouj (U. Louvain). Auditory deprivation/restoration and vestibular dysfunctions.
- Prof. Roberto Bottini (U. Trento). Semantic in the blind.
- Prof. F. Pavani (U. Trento). Medically unexplained visual loss and deafness.
- Prof. J. Jovicich (U. Trento). DTI in blind and deaf people.
- Profs Ricciardi & Cechetti (IMT Lucca). Structural brain reorganization in blind and deaf people.
- Prof Gilles Vannuscorps (UCLouvain): Brain plasticity in Moebius patients.
- Prof Arnaud Leleu (U Burgundy): Brain categorization in babies.
- Prof. Hans Op de Beeck (KULeuven): Brain correlates of sign language and Braille reading.
- Prof. Andre Mouraux (UCLouvain): Brain correlates of tactile processing
- Prof. Sylvie Nozaradan (UCLouvain) : Brain correlates of sound processing.
- Prof. Laurentius Huber (NIH- Bethesda). Layer-fMRI at 7T.
- Prof. Caroline Huart (UCLouvain): Anosmia.
- Prof. Erica Van de Walle (U. Lausanne): Audiovisual integration of socio communicative signals in vervet monkeys.
- Prof. Micah M. Murray (U. Lausanne): Objective assessment of vision in visually impaired people using EEG.
- Johan Lundström. Central mechanism of Perceptual Plasticity in Anosmia (Karolinska Institute).
- Bart Boets. Auditory processing of Autism (KULeuven).
- Daniel Margulies (CNRS+Oxford). Cortical gradients in blindness.
- Daniele Marinazzo (U. Ghent). Hemodynamic Response Estimation in blindness.
- Prof. A de Heering (UlB). Developmental cognitive neurosciences.
Ongoing Projects
- Brain (re)organization and sensory deprivation
- Multisensory representation
- How expertise in Braille and Sign language affects the brain
- Layer-dependent (re)organization of audio-visual motion processing at 7-telsas
Key publications
- Benetti S., van Ackeren M.J., Rabini G., Zonca J., Foa V., Baruffaldi F., Rezk M., Pavani F., Rossion B. and Collignon O. (2017). Functional selectivity for face processing in the right temporal “voice” area of early deaf individuals. PNAS, 114(31): E6437-E6446.
- Mattioni S., Rezk M., Battal C., Bottini R., Cuculiza Mendoza C., Oosterhof N., & Collignon O. (2020). Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind. eLife, e50732
- Rezk M, Cattoir S, Battal C, Occelli V, Mattioni S & Collignon O. (2020). Shared representation of visual and auditory motion directions in the human middle-temporal cortex. Current Biology, 2289-2299.e8
- Battal C., Gurtubay-Antolin A., Rezk M., Mattioni S., Bertonati G., Occelli V., Bottini R., Targher S., Maffei C, Jovicich J., Collignon O. (2022). Structural and functional network-level reorganization in the coding of auditory motion directions and sound source locations in the absence of vision. Journal of Neuroscience.
- Xu Y, Vignali L, Sigismondi F, Crepaldi D, Bottini R, Collignon O (2023). Similar object shape representation in the inferolateral occipitotemporal cortex of sighted and early blind people. Plos Biology