Publications

Bruxelles Woluwe

 

Selected publications

- Didier Lambert -

  1. Prevost, J.R.C.,  Kozlova, A.,  Es Saadi, B.,  Yildiz, E.,  Modaffari, S.,  Lambert, D.M.,  Pochet, L.,  Wouters, J.,  Dolušić, E.,  Frédérick, R.
    Convenient one-pot formation of highly functionalized 5-bromo-2aminothiazoles, potential endocannabinoid hydrolase MAGL inhibitors.
    Tet. Lett.  (2018) 59(49), 4315-4319
  2. El Bakali J., Muccioli GG., Body-Malapel M., Djouina M., Klupsch F., Ghinet A., Barczyk A., Renault N., Chavatte P., Desreumaux P., Lambert D.M., Millet R. 
    Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.
    ACS Med. Chem. Lett. (2014), 6(2):198-203.
  3. Kapanda C.N., Masquelier J., Labar G., Muccioli G.G., Poupaert J.H., Lambert D.M.
    Synthesis anpharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors.
    J. Med. Chem. (2012), 55: 5774-5783. 
  4. Labar G., Bauvois C., Borel F., Ferrer J.L., Wouters J., Lambert D.M.
    Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling.
    Chembiochem (2010), 11:218-27.
  5. Kapanda C.N., Muccioli G.G., Labar G., Poupaert J.H., Lambert D.M.
    Bis (dialkylaminethiocarbonyl) disulfides as potent and selective monoglyceride lipase inhibitors.
    J Med Chem. (2009), 52:7310-4.
  6. Matuszak N., Muccioli G.G., Labar G., Lambert D.M.
    Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors.
    J Med Chem. (2009), 52:7410-20.

- Raphaël Frédérick -

  1. Kozlova A, Frédérick R.
    Current state on tryptophan 2,3-dioxygenase inhibitors: a patent review (2019)
    Expert Opin Ther Pat. 29(1):11-23
  2. Spillier Q., Vertommen D., Ravez S., Marteau R., Themans Q., Corbet C., Feron O., Wouters J., Frédérick R
    Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation.
    Sci Rep. (2019) 9(1):4737.
  3. Ameryckx, A., Thabault, L., Pochet, L., Leimanis, S., Poupaert, J.H., Wouters, J., Joris, B., Van Bambeke, F., Frédérick, R.
    1(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting Dalanine-D-alanine ligase in bacterio.
    Eur. J. Med. Chem. (2018) 159, 324-338
  4. Prevost, J.R.C.,  Kozlova, A.,  Es Saadi, B.,  Yildiz, E.,  Modaffari, S.,  Lambert, D.M.,  Pochet, L.,  Wouters, J.,  Dolušić, E.,  Frédérick, R.
    Convenient one-pot formation of highly functionalized 5-bromo-2aminothiazoles, potential endocannabinoid hydrolase MAGL inhibitors.
    Tet. Lett.  (2018) 59(49), 4315-4319
  5. Ravez S, Corbet C, Spillier Q, Dutu A, Robin AD, Mullarky E, Cantley LC, Feron O, Frédérick R.
    α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH).
    J Med Chem. (2017) 60(4):1591-1597
  6. Ravez S, Spillier Q, Marteau R, Feron O, Frédérick R.
    Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy.
    J Med Chem. (2017) 60(4):1227-1237