September 01, 2021
September 1st, 2021, 5pm, Auditoire central Maisin
Arina KOZLOVA
Medicinal Chemistry (CMFA)
Design, Synthesis and Evaluation of Original 1-H-indol-3-yl Heterocyclic Derivatives as Tryptophan 2,3-Dioxygenase Inhibitors
Director : Raphaël Frédérick, co-director : Benoît Van den Eynde.
Related publications :
- Kozlova A, Frédérick R. Current State on Tryptophan 2,3-Dioxygenase Inhibitors: A Patent Review. Expert Opin. Ther. Pat. 2019, 29 (1), 11–23. doi: 10.1080/13543776.2019.1556638
- Kozlova A, Thabault L, Liberelle M, Klaessens S, Prévost JRC, Mathieu C, Pilotte L, Stroobant V, Van den Eynde B, Frédérick R. Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase. J Med Chem. 2021 Aug 2. doi: 10.1021/acs.jmedchem.1c00323.
- Kozlova A, Thabault L, Dauguet N, Stroobant V, Pilotte L, Liberelle M, Van den Eynde B, Frédérick R. Investigation of chalcogen bioisosteric replacement in a series of heterocyclic inhibitors of tryptophan 2,3-dioxygenase. Eur J Med Chem 2021. Under revision.
Info: raphael.frederick@uclouvain.be