June 21, 2023
Wednesday, June 21, 2023 – 9am - Auditoire Maisin
Sexually-dimorphic role of the constitutive androstane receptor (CAR) in the gut microbiota-liver cross-talk during non-alcoholic fatty liver disease pathogenesis
Dr. Sandrine Ellero-Simatos - Research Center for Food Toxicology (Toxalim), UMR1331 INRAe, Toulouse University, Toulouse
Related publications:
- The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice. Sharon Ann Barretto et coll. Microbiome. 2021 Apr 20;9(1):93.
- Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target. Sarra Smati et coll. Gut. 2022 Apr;71(4):807-821.
- Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism. Huillet Marine et coll. bioRXiv. April 2023.
Info: laure.bindels@uclouvain.be and laure.elens@uclouvain.be