Frédéric PEYRUSSON - TFAR FACM - Intracellular persistence of Staphylococcus aureus: From observations to mechanisms

Bruxelles Woluwe

February 09, 2021

Tuesday February 9, 2021, 5pm

Frédéric PEYRUSSON

Translational Research from Experimental and Clinical Pharmacology to Treatment Optimization (TFAR) - Cellular and Molecular Pharmacology (FACM)

Intracellular persistence of Staphylococcus aureus: From observations to mechanisms

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Promoter: Françoise Van Bambeke

Related publications:

  • Peyrusson et al. Intracellular Staphylococcus aureus persisters upon antibiotic exposure. . Nat Commun. 2020 May 4;11(1):2200. doi: 10.1038/s41467-020-15966-7.
  • Peyrusson et al. Cellular pharmacokinetics and intracellular activity of the bacterial fatty acid synthesis inhibitor, afabicin desphosphono against different resistance phenotypes of Staphylococcus aureus in models of cultured phagocytic cells. Int J Antimicrob Agents. 2020 Feb;55(2):105848. doi: 10.1016/j.ijantimicag.2019.11.005
  • Peyrusson et al. Cellular Pharmacokinetics and Intracellular Activity of Gepotidacin against Staphylococcus aureus Isolates with Different Resistance Phenotypes in Models of Cultured Phagocytic Cells. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e02245-17.
  • Peyrusson et al. Cellular pharmacokinetics and intracellular activity of the novel peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus laboratory and clinical strains with various resistance phenotypes: studies with human THP-1 monocytes and J774 murine macrophages. Antimicrob Agents Chemother. 2015 Sep;59(9):5747-60. doi: 10.1128/AAC.00827-15.

Info: francoise.vanbambeke@uclouvain.be