September 22, 2022
Thursday September 22, 2022 – 4 pm – Auditoire 51G
Laura SCHIOPPA - GNOS Research Group
Contribution to the drug development of natural and hemi-synthetic triterpenic esters as antiparasitic drugs
Promotor: Joelle Leclercq
Related publications:
- Schioppa L, Beaufay C, Bonneau N, Sanchez M, Girardi C, Leverrier A, Ortiz S, Palermo J, Poupaert JH, Quetin-Leclercq J. Design, Synthesis and Biological Activity of C3 Hemisynthetic Triterpenic Esters as Novel Antitrypanosomal Hits. ChemistryOpen. 2021 Sep;10(9):896-903. doi: 10.1002/open.202100159. PMID: 34499412; PMCID: PMC8428374.
- Schioppa L, Fall F, Ortiz S, Poupaert JH, Quetin-Leclercq J. A Validated HPLC-PDA-HRMS Method to Investigate the Biological Stability and Metabolism of Antiparasitic Triterpenic Esters. Molecules. 2021 Nov 26;26(23):7154. doi: 10.3390/molecules26237154. PMID: 34885738; PMCID: PMC8659078.
- Catteau L, Schioppa L, Beaufay C, Girardi C, Hérent MF, Frédérich M, Quetin-Leclercq J. Antiprotozoal activities of Triterpenic Acids and Ester Derivatives Isolated from the Leaves of Vitellaria paradoxa. Planta Med. 2021 Aug;87(10-11):860-867. doi: 10.1055/a-1286-1879. Epub 2020 Dec 7. PMID: 33285591.
- Fall F, Mamede L, Schioppa L, Ledoux A, De Tullio P, Michels P, Frédérich M, Quetin-Leclercq J. Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery. Metabolomics. 2022 Mar 19;18(4):20. doi: 10.1007/s11306-022-01880-0. PMID: 35305174.
Info: joelle.leclercq@uclouvain.be
