October 05, 2023
Thursday October 5, 2023 - 4 pm - Auditoire Simonart
Paola PAONE – Metabolism and Nutrition (MNUT)
Unravelling the mechanisms by which prebiotics improve metabolic disorders: interactions between gut microbes and intestinal mucus
Promotor: Prof. Patrice Cani
Related references:
- Paone P, Latousakis D, Terrasi R, Vertommen D, Jian C, Borlandelli V, Delzenne N. M., Salonen A, Juge N, Florea B. I., Muccioli G. G., Overkleeft H. S., Van Hul M., Cani P.D. The human milk oligosaccharide 2’-fucosyllactose protects against high-fat diet induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and fecal proteome profiles. Submitted in Gut in May 2023.
- Suriano F, Vieira-Silva S, Falony G, de Wouters d'Oplinter A, Paone P, Delzenne NM, Everard A, Raes J, Van Hul M, Cani PD. Fat and not sugar as the determining factor for gut microbiota changes, obesity, and related metabolic disorders in mice. Am J Physiol Endocrinol Metab. 2023; 324:E85-E96.
- Paone P, Suriano F, Jian C, Korpela K, Delzenne NM, Van Hul M, Salonen A, Cani PD. Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion. Gut Microbes. 2022; 14:2152307.
- Paone P, Cani PD. Mucus barrier, mucins and gut microbiota: the expected slimy partners? Gut 2020; 69:2232-43.
Info : patrice.cani@uclouvain.be
