In detail

Bruxelles Woluwe

Over the last 5 years, we have published 80 papers, 83% of which directed related to our research dealing with anti-infective pharmacology and drug-membrane interactions (17% as reviews or book chapters and educational papers related to anti-infective pharmacology or pharmacotherapy, papers in the field of clinical pharmacy).

Our experimental research is oriented in 6 main directions. These are, however, closely linked to one another.

  1. Lipid domains:  a promising target for new antibiotics
  2. Cholesterol enriched domains and cellular toxicity
  3. Pharmacokinetics and pharmacodynamics of antibiotics in models of persistent infections
  4. Antibiotic activity against biofilms
  5. Antibiotic efflux and permeability resistance mechanisms
  6. Novel antibiotic targets and drug design

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