Publications

- Joseph Lorent -

J.H. Lorent, Ganesan L., Rivera-Longsworth G., Levental K.R., Sezgin E., Lyman E., Levental I. (2020) “Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape " Nature Chem. Biol. 16;644-652.
Min Xie, Eveline H. W. Koch, Cornelis A. van Walree, Ana Sobota, Andreas F. P. Sonnen, J. Antoinette Killian, Eefjan Breukink & Joseph H. Lorent (2024) "Synergistic effects of oxidative and acid stress on bacterial membranes of Escherichia coli and Staphylococcus simulans" Communications Biology 7: 1161
R. Shukla, Lavore, F., Maity, S., Derks, M., Jones, C.R., Vermeulen, B., Melcorvá, A., Morris, M.A., Becker, L.M., Wang, X., Kumar, R., Medeiros-Silva, J., van Beekveld, R.A.M., Bonvin, AMJJ, J.H. Lorent, Lelli, M., Nowick, J.S.,, MacGillavry, H.D., Peoples, AJ., Spoering, AL., Ling, LL., Hughes, DE., Roos, W.H., Breukink, E., Lewis, K., M. Weingarth, (2022) “Teixobactin kills bacteria by a two-pronged attack on the cell envelope”, Nature, 608;390–396
J.H. Lorent, B.B. Diaz-Rohrer, X. Lin, K. Spring, A.A. Gorfe, K.R. Levental, I. Levental (2017). “Structural Determinants and Functional Consequences of Protein Affinity for Membrane Rafts” Nat Commun. 31;8(1):1219.
J. Lorent, C. S. Le Duff, J. Quetin-Leclercq and M. P. Mingeot-Leclercq (2013). "Induction of highly curved structures in relation to membrane permeabilization and budding by the triterpenoid saponins, alpha- and delta-Hederin." J Biol Chem. 288(20): 14000-14017.

- Marie-Paule Mingeot-Leclercq -

Mozaheb N, Mingeot-Leclercq M-P. Membrane Vesicle Production as a Bacterial Defense Against Stress. Front Microbiol. (2020) Dec 9; 11: 600221.
El Khoury M., G. Sautrey, L. Zimmermann, P. Van Der Smissen, J.-L. Décout, and Mingeot-Leclercq M-P. Targeting Bacterial Cardiolipin Enriched Microdomains: A New Promising Antimicrobial Strategy? Sci.Reports (2017), 7:10697.
Sautrey G., M. El Khoury, A. Dos Giros L. Zimmermann, M. Deleu, L. Lins, J.-L Decout and Mingeot-Leclercq M.-P. Negatively-Charged Lipids as Potential Target for New Amphiphilic Aminoglycoside Antibiotics: a biophysical study. J. Biol. Chem. (2016), 291: 13864-13874.
Mingeot-Leclercq M-P., Deleu M, Brasseur R, Dufrêne YF. Atomic force microscopy of supported lipid bilayers. Nat Protoc. (2008), 3: 1654-1659.
Mingeot-Leclercq M-P., Tulkens PM. Aminoglycosides: nephrotoxicity. Antimicrob Agents Chemother. (1999), 43:1003-1012.

- Françoise Van Bambeke -

Peyrusson F., Varet H., Nguyen T.K., Legendre R., Sismeiro O., Coppée J.Y., Wolz C., Tenson T., Van Bambeke F. Intracellular Staphylococcus aureuspersisters upon antibiotic exposure. Nature Communications (2020) 11:2200
Peyrusson F, Nguyen TK, Najdovski T, Van Bambeke F. Host cell oxidative stress induces dormant Staphylococcus aureus persisters. Microbiology Spectrum 2022; 10(1):e0231321.
Miranda Bastos A.C., Vandecasteele S.J., Spinewine A., Tulkens P.M., Van Bambeke F. Temocillin dosing in haemodialysis patients based on population pharmacokinetics of total and unbound concentrations and Monte Carlo simulations. Journal of Antimicrobial Chemotherapy (2018) 73:1630-1638
Wang G, Brunel JM, Preusse M, Mozaheb N, Willger SD, Larrouy-Maumus G, Baatsen P, Häussler S, Bolla JM, Van Bambeke F. The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence. Communications Biology 2022; 5(1):871.
Siala W., Kucharíková S., Braem A., Vleugels J., Tulkens P.M., MingeotLeclercq M-P., Van Dijck P., Van Bambeke F. The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase. Nature Communications (2016) 7:13286