Publications

Bruxelles Woluwe

Selected publications

- Patrice Cani -

  1. Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD.
    Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nature Medicine. 2019 Jul;25(7):1096-1103.
  2. Everard A.*, Plovier*, Rastelli*, Van Hul M, de Wouters d’Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de Vos WM, Luquet S, Flamand N, Di Marzo V, Cani PD
    Intestinal epithelial Nacylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis 
    Nature Communications. 2019, 28;10(1):457  
  3. Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KCH, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD.
    A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
    Nature Medicine 2017, 23:107-113  
  4. Duparc T, Plovier H, Marrachelli VG, Van Hul M, Essaghir A, Ståhlman M, Matamoros S, Geurts L, Pardo-Tendero MM, Druart C, Delzenne NM, Demoulin JB, van der Merwe SW, van Pelt J, Bäckhed F, Monleon D, Everard A, Cani PD.
    Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.
    Gut. 2017 66(4):620-632   
  5. Geurts L, Everard A*, Van Hul M*, Essaghir A, Duparc T, Matamoros S, Plovier H, Castel J, Denis RGP, Bergiers M, Druart C, Alhouayek M, Delzenne NM, Muccioli GG, Demoulin JB, Luquet S, Cani PD.
    Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
    Nature Communications. 2015, 6:6495   
  6. Everard A, Geurts L, Caesar R, Van Hul M, Matamoros M, Duparc T, Denis RGP, Cochez P, Pierard P, Castel J, Bindels LB, Plovier H , Robine R, Muccioli GG, Renauld JC, Dumoutier L, Delzenne NM, Luquet S, Bäckhed F, Cani PD
    Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status
    Nature Communications. 2014, 5;5:5648
  7. Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD.
    Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
    Proc Natl Acad Sci U S A. 2013, 110, 9066-71

- Nathalie Delzenne -

  1. Olivares M, Rodriguez J, Pötgens SA, Neyrinck AM, Cani PD, Bindels LB, Delzenne NM.
    The Janus Face of Cereals: Wheat-Derived Prebiotics Counteract the Detrimental Effect of Gluten on Metabolic Homeostasis in Mice Fed a High-Fat/High-Sucrose Diet.
    Mol Nutr Food Res. 2019 Oct 13: e1900632. doi: 10.1002/mnfr.201900632. [Epub ahead of print]
  2. Hiel S, Bindels LB, Pachikian BD, Kalala G, Broers V, Zamariola G, Chang BPI, Kambashi B, Rodriguez J, Cani PD, Neyrinck AM, Thissen JP, Luminet O, Bindelle J, Delzenne NM.
    Effects of a diet based on inulin-rich vegetables on gut health and nutritional behavior in healthy humans.
    Am J Clin Nutr. 2019 Jun 1;109(6):1683-1695.
  3. Neyrinck AM, Catry E, Taminiau B, Cani PD, Bindels LB, Daube G, Dessy C, Delzenne NM.
    Chitin-glucan and pomegranate polyphenols improve endothelial dysfunction.
    Sci Rep. 2019 Oct 2;9(1):14150.
  4. Beaumont M, Neyrinck AM, Olivares M, Rodriguez J, de Rocca Serra A, Roumain M, Bindels LB, Cani PD, Evenepoel P, Muccioli GG, Demoulin JB, Delzenne NM.
    The gut microbiota metabolite indole alleviates liver inflammation in mice. 
    FASEB J. 2018 ; Jun 15 fj201800544
  5. Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM.
    Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.
    Gut. 2018 Feb;67(2):271-283.  
  6. Olivares M, Neyrinck AM, Pötgens SA, Beaumont M, Salazar N, Cani PD, Bindels LB, Delzenne NM.
    The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice. 
    Diabetologia. 2018; 61(8):1838-1848.
  7. Suriano F, Bindels LB, Verspreet J, Courtin CM, Verbeke K, Cani PD, Neyrinck AM, Delzenne NM.
    Fat binding capacity and modulation of the gut microbiota both determine the effect of wheat bran fractions on adiposity.
    Sci Rep. 2017; 7:5621.
  8. Leclercq S., Matamoros S., Cani P.D., Neyrinck A.M., Jamar F., Stärkel P., Windey K., Tremaroli V., Bäckhed F., Verbeke K., de Timary P., Delzenne N.M.
    Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity.
    Proc Natl Acad Sci USA. (2014), 111: E4485-93.

- Laure Bindels -

  1. Pötgens SA, Brossel H, Sboarina M, Catry E, Cani PD, Neyrinck AM, Delzenne NM, Bindels LB.
    Klebsiella oxytoca expands in cancer cachexia and acts as a gut pathobiont contributing to intestinal dysfunction.
    Sci Rep, 2018.
  2. Bindels L.B., Neyrinck A.M., Claus S.P., Le Roy C.I., Grangette C., Pot B., Martinez I., Walter J., Cani P.D., Delzenne N.M.
    Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia.
    The ISME J, 2016.
  3. Bindels LB, Segura Munoz RR, GomesNeto JC, Mutemberezi V, Martínez I, Salazar N, Cody EA, Quintero-Villegas MI, Kittana H, de Los Reyes-Gavilán CG, Schmaltz RJ, Muccioli GG, Walter J, RamerTait AE.
    Resistant starch can improve insulin sensitivity independently of the gut microbiota.
    Microbiome, 2017.
  4. Bindels LB, Delzenne NM, Cani PD, Walter J.
    Towards a more comprehensive concept for prebiotics.
    Nat Rev Gastroenterol Hepatol, 2015.
  5. Bindels LB, Porporato P, Dewulf EM, Verrax J, Neyrinck AM, Martin JC, Scott KP, Buc Calderon P, Feron O, Muccioli GG, Sonveaux P, Cani PD, Delzenne NM.
    Gut microbiota-derived propionate reduces cancer cell proliferation in the liver.
    Br J Cancer, 2013. 

- Amandine Everard -

  1. Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD.
    Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
    Nature Medicine. 2019 Jul;25(7):1096-1103.
  2. Everard A.*, Plovier*, Rastelli*, Van Hul M, de Wouters d’Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de  Vos WM, Luquet S, Flamand N, Di Marzo V, Cani PD
    Intestinal epithelial Nacylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis 
    Nature Communications. 2019, 28;10(1):457
  3. Delbès AS, Castel J, Denis RGP, Morel C, Quiñones M, Everard A, Cani PD, Massiera F, Luquet SH.
    Prebiotics Supplementation Impact on the Reinforcing and Motivational Aspect of Feeding.
    Frontiers in Endocrinology. 2018, 9:273  
  4. Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KCH, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD.
    A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
    Nature Medicine 2017, 23:107-113  
  5. Duparc T, Plovier H, Marrachelli VG, Van Hul M, Essaghir A, Ståhlman M, Matamoros S, Geurts L, Pardo-Tendero MM, Druart C, Delzenne NM, Demoulin JB, van der Merwe SW, van Pelt J, Bäckhed F, Monleon D, Everard A, Cani PD.
    Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.
    Gut. 2017, 66(4):620-632 
  6. Everard A, Geurts L, Caesar R, Van Hul M, Matamoros M, Duparc T, Denis RGP, Cochez P, Pierard P, Castel J, Bindels LB, Plovier H , Robine R, Muccioli GG, Renauld JC, Dumoutier L, Delzenne NM, Luquet S, Bäckhed F, Cani PD
  7. Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status
    Nature Communications. 2014, 5;5:5648  
  8. Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD.
    Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
    Proc Natl Acad Sci U S A. 2013, 110, 9066-71