Publications

SELECTED PUBLICATIONS

1. Le Roy T*, Moens de Hase E*, Van Hul M, Paquot A, Pelicaen R, Régnier M, Depommier C, Druart C, Everard A, Maiter D, Delzenne NM, Bindels LB, de Barsy M, Loumaye A, Hermans MP, Thissen JP, Vieira-Silva S, Falony G, Raes J, Muccioli GG, Cani PD.
   Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice.
   Gut. Gut. 2022 Mar;71(3):534-543.
2. Abot A, Wemelle E, Laurens C, Paquot A, Pomie N, Carper D, Bessac A, Mas Orea X, Fremez C, Fontanie M, Lucas A, Lesage J, Everard A, Meunier E, Dietrich G, Muccioli GG, Moro C, Cani PD*, Knauf C*. (co-senior and co-corresponding authors)
   Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice.
   Gut. 2021 Jun;70(6):1078-1087.
3. Cani PD, Depommier C, Derrien M, Everard A, de Vos WM.
   Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms.
   Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637.
4. Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD.
   Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
   Nature Medicine. 2019 Jul;25(7):1096-1103.
5. Everard A.*, Plovier*, Rastelli*, Van Hul M, de Wouters d’Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de Vos WM, Luquet S, Flamand N, Di Marzo V, Cani PD
   Intestinal epithelial Nacylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis 
   Nature Communications. 2019, 28;10(1):457  
6. Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KCH, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD.
   A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
   Nature Medicine 2017, 23:107-113  
7. Geurts L, Everard A*, Van Hul M*, Essaghir A, Duparc T, Matamoros S, Plovier H, Castel J, Denis RGP, Bergiers M, Druart C, Alhouayek M, Delzenne NM, Muccioli GG, Demoulin JB, Luquet S, Cani PD.
   Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
   Nature Communications. 2015, 6:6495   
8. Everard A, Geurts L, Caesar R, Van Hul M, Matamoros M, Duparc T, Denis RGP, Cochez P, Pierard P, Castel J, Bindels LB, Plovier H , Robine R, Muccioli GG, Renauld JC, Dumoutier L, Delzenne NM, Luquet S, Bäckhed F, Cani PD
   Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status
   Nature Communications. 2014, 5;5:5648
9. Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD.
   Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
   Proc Natl Acad Sci U S A. 2013, 110, 9066-71

COMPLETE LIST

1. Rodriguez J, Neyrinck AM, Van Kerckhoven M, Gianfrancesco MA, Renguet E, Bertrand L, Cani PD, Lanthier N, Cnop M, Paquot N, Thissen JP, Bindels LB, Delzenne NM.
   Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals.
   BMC Med. 2022 Mar 30;20(1):110
2. Neyrinck AM, Rodriguez J, Zhang Z, Nazare JA, Bindels LB, Cani PD, Maquet V, Laville M, Bischoff SC, Walter J, Delzenne NM.
   Breath volatile metabolome reveals the impact of dietary fibres on the gut microbiota: Proof of concept in healthy volunteers.
   EBioMedicine. 2022 Jun;80:104051
3. Leyrolle Q, Cserjesi R, Mulders MDGH, Zamariola G, Hiel S, Gianfrancesco MA, Rodriguez J, Portheault D, Amadieu C, Leclercq S, Bindels LB, Neyrinck AM, Cani PD, Karkkainen O, Haninheva K, Lanthier N, Trefois P, Paquot N, Cnop M, Thissen JP, Klein O, Luminet O, Delzenne NM.
   Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients.
   Clin Nutr. 2021 Apr;40(4):2035-2044.
4. Rodriguez J, Neyrinck AM, Zhang Z, Seethaler B, Nazare JA, Robles Sánchez C, Roumain M, Muccioli GG, Bindels LB, Cani PD, Maquet V, Laville M, Bischoff SC, Walter J, Delzenne NM.
   Metabolite profiling reveals the interaction of chitin-glucan with the gut microbiota.
   Gut Microbes. 2020 Nov 9;12(1):1810530.
5. Rodriguez J, Hiel S, Neyrinck AM, Le Roy T, Pötgens SA, Leyrolle Q, Pachikian BD, Gianfrancesco MA, Cani PD, Paquot N, Cnop M, Lanthier N, Thissen JP, Bindels LB, Delzenne NM.
   Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients.
   Gut. 2020 Nov;69(11):1975-1987.
6. Neyrinck AM, Rodriguez J, Zhang Z, Seethaler B, Mailleux F, Vercammen J, Bindels LB, Cani PD, Nazare JA, Maquet V, Laville M, Bischoff SC, Walter J, Delzenne NM.
   Noninvasive monitoring of fibre fermentation in healthy volunteers by analyzing breath volatile metabolites: lessons from the FiberTAG intervention study.
   Gut Microbes. 2021;13(1):1-16.
7. Neyrinck AM, Rodriguez J, Zhang Z, Seethaler B, Sánchez CR, Roumain M, Hiel S, Bindels LB, Cani PD, Paquot N, Cnop M, Nazare JA, Laville M, Muccioli GG, Bischoff SC, Walter J, Thissen JP, Delzenne NM.
   Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial.
   Eur J Nutr. 2021 Sep;60(6):3159-3170
8. Amadieu C, Leclercq S, Coste V, Thijssen V, Neyrinck AM, Bindels LB, Cani PD, Piessevaux H, Stärkel P, de Timary P, Delzenne NM.
   Dietary fiber deficiency as a component of malnutrition associated with psychological alterations in alcohol use disorder.
   Clin Nutr. 2021 May;40(5):2673-2682.

COMPLETE LIST

1. Thibaut MM, Gillard J, Dolly A, Roumain M, Leclercq IA, Delzenne NM, Muccioli GG, Bindels LB.
   Bile Acid Dysregulation Is Intrinsically Related to Cachexia in Tumor-Bearing Mice.
   Cancers (Basel) 2021.
2. Pötgens SA, Thibaut MM, Joudiou N, Sboarina M, Neyrinck AM, Cani PD, Claus SP, Delzenne NM, Bindels LB.
   Multi-compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice.
   J Cach Sarc Muscle 2021.
3. Thibaut MM, Sboarina M, Roumain M, Pötgens SA, Neyrinck AM, Destrée F, Gillard J, Leclercq I, Dachy G, Rastelli M, Everard A, Cani PD, Porporato P, Loumaye A, Thissen JP, Muccioli GG, Delzenne NM, Bindels LB.
   Inflammation-induced cholestasis in cancer cachexia.
   J Cach Sarc Muscle 2021.
4. Bindels LB, Segura Munoz RR, GomesNeto JC, Mutemberezi V, Martínez I, Salazar N, Cody EA, Quintero-Villegas MI, Kittana H, de Los Reyes-Gavilán CG, Schmaltz RJ, Muccioli GG, Walter J, RamerTait AE.
   Resistant starch can improve insulin sensitivity independently of the gut microbiota.
   Microbiome, 2017.
5. Bindels L.B., Neyrinck A.M., Claus S.P., Le Roy C.I., Grangette C., Pot B., Martinez I., Walter J., Cani P.D., Delzenne N.M.
   Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia.
   The ISME J, 2016.
6. Bindels LB, Delzenne NM, Cani PD, Walter J.
   Towards a more comprehensive concept for prebiotics.
   Nat Rev Gastroenterol Hepatol, 2015.
7. Bindels LB, Porporato P, Dewulf EM, Verrax J, Neyrinck AM, Martin JC, Scott KP, Buc Calderon P, Feron O, Muccioli GG, Sonveaux P, Cani PD, Delzenne NM.
   Gut microbiota-derived propionate reduces cancer cell proliferation in the liver.
   Br J Cancer, 2013. 

COMPLETE LIST

1. de Wouters d'Oplinter A, Verce M, Huwart SJP, Lessard-Lord J, Depommier C, Van Hul M, Desjardins Y, Cani PD, Everard A. 
   Obese-associated gut microbes and derived phenolic metabolite as mediators of excessive motivation for food reward. 
   Microbiome. 2023 Apr 28;11(1):94. doi: 10.1186/s40168-023-01526-w.PMID: 37106463 Free PMC article.
2. Huwart SJP, de Wouters d'Oplinter A, Rastelli M, Van Hul M, de Vos WM, Luquet S, Cani PD, & Everard A.
   Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of Akkermansia muciniphila.
   Cells, 2022, Aug 16;11(16):2534
3. de Wouters d'Oplinter A, Huwart SJP, Cani PD, & Everard A.
   Gut microbes and food reward: From the gut to the brain.
   Frontiers in neuroscience, 2022 Jul 25;16:947240
4. de Wouters d'Oplinter A, Rastelli M, Van Hul M, Delzenne NM, Cani PD, Everard A.
   Gut microbes participate in food preference alterations during obesity.
   Gut Microbes. 2021 Jan-Dec;13(1):1959242
5. Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD.
   Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
   Nature Medicine. 2019 Jul;25(7):1096-1103.
6. Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KCH, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD.
   A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
   Nature Medicine 2017, 23:107-113  
7. Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD.
   Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
   Proc Natl Acad Sci U S A. 2013, 110, 9066-71

COMPLETE LIST