Theses

Bruxelles Woluwe

THESES IN PROGRESS

Ancia Marine
Towards a better understanding of the Alternative Lengthening of Telomeres mechanism by the discovery of TSPYL5/USP7 protein-protein interaction inhibitors.
Director: Raphaël Frédérick; Co-director: Anabelle Decottignies

Brustenga Chiara
LDH disruptors for anticancer therapy
Director: Raphaël Frédérick; Co-director: Pierre Sonveaux

Dechenne Juhans
lnterrogating the self-assembly of arginase and tryptophan 2,3-dioxygenase, two proteins involved in cancer immunotherapy
Director: Raphaël Frédérick

Deskeuvre Marine
Low Insertion Peptides (pHLIP) - drug conjugates as a novel tumor targeting strategy: design, chemical synthesis, biophysical characterization and in vitro evaluation.
Director: Raphaël Frédérick; Co-director: Olivier Feron

Lacour Séraphin
Design, synthesis and evaluation of new pharmacological tools to study tryptophan-2,3-dioxygenase (TDO2) in cancer immunotherapy
Director: Raphaël Frédérick

Leone Giuditta
Inhaled vasodilator nanomedicine.
Director: Rita Vanbever; Co-director: Raphaël Frédérick

Marteau Romain
Development of ACSL4’s selective ligands: new tools to target ferrop.
Director: Raphaël Frédérick; Co-director: Séverine Ravez (Univ. lille2, France)

Mazhari Darius
Deciphering the exact role of the acyl-CoA synthetase long-chain family member 4 (ACSL4) in cancer”
Director: Raphaël Frédérick; Co-director: Jamal El Bakali (Univ. lille2, France)

Pierrard François
Development of new chemical tools for interrogating the lactate dehydrogenase B (LDHB) tetramerization site with stapled peptides”
Director: Olivier Riant; Co-Director: Raphaël Frédérick

Prévost Julien
Design and synthesis of Arg1 inhibitors for anticancer immunotherapy
Director: Raphaël Frédérick

Savoyen Perrine
Design and synthesis of peptide macrocycles as inhibitors of lactate dehydrogenase.
Director: Raphaël Frédérick; Co-director: Pierre Sonveaux

Tan Yonghua
Biocompatible catalysts to release prodrugs
Director: Olivier Riant; Co-director: Raphaël Frédérick