Theses

Bruxelles Woluwe

Theses in progress

Ancia Marine

“Towards a better understanding of the Alternative Lengthening of Telomeres mechanism by the discovery of TSPYL5/USP7 protein-protein interaction inhibitors”
Director: Raphaël Frédérick; Co-director: Anabelle Decottignies

Brustenga Chiara

“LDH disruptors for anticancer therapy”
Director: Raphaël Frédérick; Co-director: Pierre Sonveaux

Dechenne Juhans

“lnterrogating the self-assembly of arginase and tryptophan 2,3-dioxygenase, two proteins involved in cancer immunotherapy”
Director: Raphaël Frédérick

Deskeuvre Marine

“pH Low Insertion Peptides (pHLIP) - drug conjugates as a novel tumor targeting strategy: design, chemical synthesis, biophysical characterization and in vitro evaluation”
Director: Raphaël Frédérick; Co-director: Olivier Feron

Kozlova Arina

“Towards the discovery of dual inhibitors of IDO and TDO, two promising targets for anticancer immunotherapy”
Director: Raphaël Frédérick; Co-director: Benoit Van den Eynde

Leone Giuditta

“Inhaled vasodilator nanomedicine”
Director: Rita Vanbever; Co-director: Raphaël Frédérick

Marteau Romain

“Development of ACSL4’s selective ligands: new tools to target ferroptosis”
Director: Raphaël Frédérick; Co-director: Séverine Ravez (Univ. lille2, France)

Prévost Julien

“Design and synthesis of Arg1 inhibitors for anticancer immunotherapy”
Director: Raphaël Frédérick

Savoyen Perrine

“Design and synthesis of peptide macrocycles as inhibitors of lactate dehydrogenase”
Director: Raphaël Frédérick; Co-director: Pierre Sonveaux

Tan Yonghua

“Biocompatible catalysts to release prodrugs”
Director: Olivier Riant; Co-director: Raphaël Frédérick