Technical and scientific expertise
- Quantitative analysis of endogenous and exogenous molecules in biological matrices
- Recognised expertise in lipid mediators and secondary plant metabolites (quantification, structural identification, etc.)
- Complete development of chromatographic methods coupled with mass spectrometric detection
- Validation of chromatographic methods (LC-MS, LC-UV, etc.)
- Support for data interpretation and project/manuscript writing
Main equipment
- High-resolution mass spectrometer coupled with a liquid chromatography system (UHPLC-HRMS LTQ-Orbitrap XL)
- High-sensitivity mass spectrometer coupled with a liquid chromatography system (UHPLC-MS/MS Xevo TQ-S)
- Several chromatographic systems (HPLC, UPLC, GC) using UV, DAD or FID detectors
Get an overview of the platform’s facilities via a virtual tour.
Applications
- Identification and quantification of metabolites and compounds of pharmacological interest from complex matrices: biological fluids, tissues, cells, plants, etc.
- Quantification of lipid mediators (bile acids, endocannabinoids, oxysterols, phospholipids, short chain fatty acids, etc.)
- Structural identification of endogenous and xenobiotic derived metabolites
- Identification and quantification of secondary metabolites of natural origin
- Development and validation of LC-MS methods
Services available to
- UCLouvain students and researchers
- External collaborations