In a dynamic environment, human subjects often make anticipatory eye movements to shift the visual axis towards the position where a stimulus of interest is likely to appear next. However, anticipation has to adapt to the inherently stochastic nature of physical events that can impact cognitive control and be psychologically distressing. Moreover, anticipatory actions require to keep track of elapsed time and inhibitory control. These cognitive functions could be impacted in neuropsychiatric diseases like Parkinson's.
Team members
Collaborations
- Dr Pierre Pouget, Institut du Cerveau et de la Moëlle Epinière
Ongoing Projects
Crédit de Recherche (CDR) - Exercice 2024
J.0152.24 (Référence e-space : 40020734)
"Uncertainty and anticipation"
Key publications
- Degos B, Pouget P, Missal M (2022) From anticipation to impulsivity in Parkinson's disease. Nature Parkinson Journal (npj) Parkinson’s Dis. 8(1):125.
- Missal M, Heinen SJ (2017) Stopping smooth pursuit. Philos Trans R Soc Lond B Biol Sci. 372(1718). Review.
- Nozaradan S, Peretz I, Missal M, Mouraux A (2011) Tagging the neuronal entrainment to beat and meter. J Neurosci. 31:10234-40.
- Badler J, Lefèvre P, Missal M (2010) Causality attribution biases oculomotor responses. J Neurosci. 30:10517-25.
- de Hemptinne C, Lefèvre P, Missal M (2008) Neuronal bases of directional expectation and anticipatory pursuit. J Neurosci. 28:4298-310.
- de Hemptinne C, Nozaradan S, Duvivier Q, Lefèvre P, Missal M (2007) How do primates anticipate uncertain future events? J Neurosci. 27:4334-41.