Jean-Christophe Jonas, PI


Jean-Christophe Jonas trained as an MD at UCL, then started a scientific career in field of pancreatic beta-cell physiology and pathophysiology in the context of type 2 diabetes under the supervision of leading experts in the field, Jean-Claude Henquin at UCL, Claes Wollheim at the Centre Médical Universitaire-Université de Genève, and Gordon Weir at the Joslin Diabetes Center-Harvard Medical School in Boston.

Jean-Christophe Jonas is:

  • Research Director of the Fonds de la Recherche Scientifique-FNRS
  • Professor of pathophysiology and pharmacology of endocrine systems at the Faculty of Pharmacy and Biomedical Sciences
  • Head of the Pole of Endocrinology, Diabetes and Nutrition at the Université catholique de Louvain


  • Contribute to our understanding of type 2 diabetes and improve its treatment or prevention

Research interests:

  • Role of glucotoxicity in beta-cell demise under metabolic stress conditions, focusing on the alterations of the beta-cell phenotype by ER stress and oxidative stress
  • Stimulus-secretion coupling events in insulin-producing beta-cells
  • Dynamic changes in beta-cell redox state at the subcellular level

Further informations at:


Mr Jean-Christophe Jonas

Directeur de recherche FNRS

SSS/FASB  --  Faculté de pharmacie et des sciences biomédicales (FASB)

SSS/IREC  --  Institut de recherche expérimentale et clinique (IREC)

SSS/IREC/EDIN  --  Pôle d'endocrinologie, diabète et nutrition (EDIN)

Avenue Hippocrate 55/B1.55.06
1200 Woluwe-Saint-Lambert