Jean-Christophe Jonas trained as an MD at UCL, then started a scientific career in field of pancreatic beta-cell physiology and pathophysiology in the context of type 2 diabetes under the supervision of leading experts in the field, Jean-Claude Henquin at UCL, Claes Wollheim at the Centre Médical Universitaire-Université de Genève, and Gordon Weir at the Joslin Diabetes Center-Harvard Medical School in Boston.

Jean-Christophe Jonas is:

Research Director of the Fonds de la Recherche Scientifique-FNRS
Professor of pathophysiology and pharmacology of endocrine systems at the Faculty of Pharmacy and Biomedical Sciences
Head of the Pole of Endocrinology, Diabetes and Nutrition at the Université catholique de Louvain

Objective:

Contribute to our understanding of type 2 diabetes and improve its treatment or prevention

Research interests:

Role of glucotoxicity in beta-cell demise under metabolic stress conditions, focusing on the alterations of the beta-cell phenotype by ER stress and oxidative stress
Stimulus-secretion coupling events in insulin-producing beta-cells
Dynamic changes in beta-cell redox state at the subcellular level