Publications sélectionnées
FATH
2023
Michel, Lauriane ; Esfahani, Hrag ; Verdoy, Roxane ; de Mulder, Delphine ; Ambroise, Jérôme ; Roelants, Véronique ; Bouchard Bertrand ; Savary, Jérôme ; Dewulf, Joseph P ; Doumont, Thomas ; Bouzin, Caroline ; Haufroid, Vincent ; Luiken, Joost J.F.P. ; Nabben, Miranda ; Singleton, Michael L. ; Bertrand, Luc ; Ruiz, Matthieu ; Des Rosiers, Christine ; Balligand, Jean-Luc. A NRF2/beta3-adrenoreceptor axis drives a sustained antioxidant and metabolic rewiring through the pentose-phosphate pathway to alleviate cardiac stress. In: Biorxiv, Vol. 14, no. Nov (2023) (2023). doi:10.1101/2023.11.10.564735.
2023
Gallez, Bernard ; Mathieu, Barbara ; Sonveaux, Pierre. About metformin and its action on the mitochondrial respiratory chain in prostate cancer. In: Translational Andrology and Urology, (2023) (Accepté/Sous presse).
2023
Gress, Verena ; Roussy, Mathieu ; Boulianne, Luc ; Bilodeau, Mélanie ; Cardin, Sophie ; El-Hachem, Nehme ; Lisi, Véronique ; Khakipoor, Banafsheh ; Rouette, Alexandre ; Farah, Azer ; Théret, Louis ; Aubert, Léo ; Fatima, Furat ; Audemard, Eric ; Thibault, Pierre ; Bonneil, Éric ; Chagraoui, Jalila ; Laramée, Louise ; Gendron, Patrick ; Jouan, Loubna ; Jammali, Safa ; Paré, Bastien ; Simpson, Shawn M ; Tran, Thai Hoa ; Duval, Michel ; Teira, Pierre ; Bittencourt, Henrique ; Santiago, Raoul ; Barabé, Frédéric ; Sauvageau, Guy ; Smith, Martin A ; Hébert, Josée ; Roux, Philippe P ; Gruber, Tanja A ; Lavallée, Vincent-Philippe ; Wilhelm, Brian T ; Cellot, Sonia. CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.. In: Blood advances, (2023). doi:10.1182/bloodadvances.2022008899 (Accepté/Sous presse).
2023
Balligand, Jean-Luc ; Michel, Lauriane. Clinical pharmacology of β-3 adrenergic receptor agonists for cardiovascular diseases. In: Expert Review of Clinical Pharmacology, Vol. 16, no.11, p. 1073-1084 (2023). doi:10.1080/17512433.2023.2193681.
2023
Michel, Lauriane. Extracellular Vesicles in Adipose Tissue Communication with the Healthy and Pathological Heart. In: International Journal of Molecular Sciences, Vol. 24, no.9, p. 7745 (2023). doi:10.3390/ijms24097745.
2023
Van den Bossche, Valentin ; Vignau, Julie ; Vigneron, Engy ; Zaryouh, Hannah ; Wouters, An ; Ambroise, Jérôme ; Van Laere, Steven ; Mignion, Lionel ; Lepicard, Elise ; Jordan, Bénédicte ; Guilbaud, Céline ; Dahou, Hajar ; Mendola, Antonella ; Desgres, Manon ; Aubert, Léo ; Gerin, Isabelle ; Bommer, Guido ; Boidot, Romain ; Vermonden, Perrine ; Warnant, Aurélien ; Larondelle, Yvan ; Machiels, Jean-Pascal ; Feron, Olivier ; Schmitz, Sandra ; Corbet, Cyril. PPARα-mediated fatty acid metabolism reprogramming supports resistance to anti-EGFR targeted therapy in head and neck squamous cell carcinoma. In: Nature Communications, (2023) (Soumis).
2023
Kerkhove, Lisa ; Geirnaert, Febe ; Rifi, Amir Laraki ; Law, Ka Lun ; Gutiérrez, Adrián ; Oudaert, Inge ; Corbet, Cyril ; Gevaert, Thierry ; Dufait, Inès ; De Ridder, Mark. Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer. In: Cancers, Vol. 15, no.8, p. 2363 (2023). doi:10.3390/cancers15082363.
2023
Balligand, Jean-Luc ; Brito, Dulce ; Brosteanu, Oana ; Casadei, Barbara ; Depoix, Christophe ; Edelmann, Frank ; Ferreira, Vanessa ; Filippatos, Gerasimos ; Gerber, Bernhard ; Gruson, Damien ; Hasenclever, Dirk ; Hellenkamp, Kristian ; Ikonomidis, Ignatios ; Krakowiak, Bartosz ; Lhommel, Renaud ; Mahmod, Masliza ; Neubauer, Stefan ; Persu, Alexandre ; Piechnik, Stefan ; Pieske, Burkert ; Pieske-Kraigher, Elisabeth ; Pinto, Fausto ; Ponikowski, Piotr ; Senni, Michele ; Trochu, Jean-Noël ; Van Overstraeten, Nancy ; Wachter, Rolf ; Pouleur, Anne-Catherine. Repurposing the β3-Adrenergic Receptor Agonist Mirabegron in Patients With Structural Cardiac Disease: The Beta3-LVH Phase 2b Randomized Clinical Trial.. In: JAMA cardiology, Vol. 8, no.11, p. 1031-1040 (2023). doi:10.1001/jamacardio.2023.3003.
2023
Spinella, Jean-François ; Theret, Louis ; Aubert, Léo ; Audemard, Eric ; Boucher, Geneviève ; Pfammatter, Sybille ; Bonneil, Eric ; Bordeleau, Marie-Ève ; Thibault, Pierre ; Hébert, Josée ; Roux, Philippe P ; Sauvageau, Guy. SPAT: Surface Protein Annotation Tool. In: bioRxiv, (2023). doi:10.1101/2023.07.07.547075 (Accepté/Sous presse).
2023
Colson, Arthur ; Depoix, Christophe ; Lambert, Isaline ; Leducq, Camille ; Bedin, Marie ; De Beukelaer, Michèle ; Gatto, Laurent ; Loriot, Axelle ; Peers de Nieuwburgh, Maureen ; Bouhna, Khadija ; Baldin, Paméla ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Specific hypoxia-inducible factor-2 (HIF-2α) inhibitor PT2385 mitigates placental dysfunction in vitro and in a rat model of preeclampsia (RUPP). In: Hypertension., Vol. 80, no. 5, p. 1011-1023 (2023). doi:10.1161/HYPERTENSIONAHA.122.20739.
2023
Tan, Yonghua ; Lefevre, Marine ; Pierrard, François ; Soetens, Mathieu ; Shoueiry, Maria ; Yildiz, Esra ; Ibanez, Sébastien ; Ozkan, Kubra ; Feron, Olivier ; Frédérick, Raphaël ; Riant, Olivier. Tandem Heck/Tsuji-Trost Reaction for Uncaging of Alloc-Protected Amines with Palladium Complexes in Living Cells. In: Journal of Organometallic Chemistry, Vol. 996, no.-, p. 122743 (2023). doi:10.1016/j.jorganchem.2023.122743.
2022
Belo do Nascimento Osorio de Castro, Inês ; Verfaillie, Marie ; Gamze, Ates ; Beckers, Pauline ; Joris, Virginie ; Desmet, Nathalie ; Massie, Ann ; Hermans, Emmanuel. AMPK Modulates the Metabolic Adaptation of C6 Glioma Cells in Glucose-Deprived Conditions without Affecting Glutamate Transport. In: Cells, Vol. 11, no. 11, p. 1800 [1-18] (2022). doi:10.3390/cells11111800.
2022
Descamps, Olivier ; Demeure, Fabian ; Mertens, Ann ; Verhaegen, Ann ; Balligand, Jean-Luc ; Langlois, Michel ; Wallemacq, Caroline ; De Sutter, Johan ; Cals, Nathalie ; Rietzschel, Ernst. Acide bempédoïque : nouvelle option thérapeutique pour améliorer le profil lipidique des patients à risque cardiovasculaire élevé. In: Louvain médical, Vol. 141, no.3, p. 153-161 (2022).
2022
Spourquet, Catherine ; Delcorte, Ophélie ; Lemoine, Pascale ; Dauguet, Nicolas ; Loriot, Axelle ; Achouri, Younes ; Hollmén, Maija ; Jalkanen, Sirpa ; Huaux, François ; Lucas, Sophie ; Van Meerbeeck, Pierre ; Knauf, Jeffrey ; Fagin, James A. ; Dessy, Chantal ; Mourad, Michel ; Henriet, Patrick ; Tyteca, Donatienne ; Marbaix, Etienne ; Pierreux, Christophe. BRAFV600E expression in thyrocytes causes recruitment of immunosuppressive STABILIN-1 macrophages. In: Cancers, Vol. 14, no. 19, p. 4687 [1-21] (2022). doi:10.3390/cancers14194687.
2022
Boughaleb, Hasnae ; Lobysheva, Irina ; Dei Zotti, Flavia ; Balligand, Jean-Luc ; Montiel, Virginie. Biological Assessment of the NO-Dependent Endothelial Function.. In: Molecules, Vol. 27, no.22, p. 7921 [1-18] (2022). doi:10.3390/molecules27227921.
2022
Kerick, Martin ; Acosta-Herrera, Marialbert ; Simeón-Aznar, Carmen Pilar ; Callejas, José Luis ; Assassi, Shervin ; Proudman, Susanna M ; Nikpour, Mandana ; Hunzelmann, Nicolas ; Moroncini, Gianluca ; de Vries-Bouwstra, Jeska K ; Orozco, Gisela ; Barton, Anne ; Herrick, Ariane L ; Terao, Chikashi ; Allanore, Yannick ; Fonseca, Carmen ; Alarcón-Riquelme, Marta Eugenia ; Radstake, Timothy R D J ; Beretta, Lorenzo ; Denton, Christopher P ; Mayes, Maureen D ; Martin, Javier. Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis., collab. International SSc Group ; Australian Scleroderma Interest Group (ASIG) ; PRECISESADS Clinical Consortium ; PRECISESADS Clinical Consortium ; Lauwerys, Bernard ; Ducreux, Julie ; Maudoux, Anne-Lise. In: NPJ genomic medicine, Vol. 7, no.1, p. 57 [1-12] (2022). doi:10.1038/s41525-022-00327-8.
2022
Bernard, Alfred. Dermal Exposure to Hazardous Chemicals in Baby Diapers: A Re-Evaluation of the Quantitative Health Risk Assessment Conducted by The French Agency for Food, Environmental and Occupational Health and Safety (ANSES).. In: International journal of environmental research and public health, Vol. 19, no.7, p. 4159 [1-18] (2022). doi:10.3390/ijerph19074159.
2022
Choteau, Mathilde ; Scohy, Anaïs ; Messe, Stéphane ; Luyckx, Mathieu ; Dechamps, Mélanie ; Montiel, Virginie ; Yombi, Jean Cyr ; Gruson, Damien ; Limaye, Nisha ; Michiels, Thomas ; Dumoutier, Laure. Development of SARS-CoV2 humoral response including neutralizing antibodies is not sufficient to protect patients against fatal infection.. In: Scientific reports, Vol. 12, no. 1, p. 2077 [1-12] (2022). doi:10.1038/s41598-022-06038-5.
2022
Tallarico, Roberta Teixeira ; Deniau, Benjamin ; Fong, Nicholas ; Ghosn, Jade ; Legrand, Matthieu. Differences in HADS and SF-36 scores 1 year after critical illness in COVID-19 patients., collab. French-COVID and the FROG-ICU Investigators ; Laterre, Pierre-François ; Montiel, Virginie ; Dujardin, Marie-France ; Berghe, Caroline. In: Intensive care medicine, Vol. 48, no.9, p. 1245-1247 (2022). doi:10.1007/s00134-022-06797-9.
2022
Trouvilliez, Sarah ; Cicero, Julien ; Lévêque, Romain ; Aubert, Léo ; Corbet, Cyril ; Van Outryve, Alexandre ; Streule, Karolin ; Angrand, Pierre-Olivier ; Völkel, Pamela ; Magnez, Romain ; Brysbaert, Guillaume ; Mysiorek, Caroline ; Gosselet, Fabien ; Bourette, Roland ; Adriaenssens, Eric ; Thuru, Xavier ; Lagadec, Chann ; de Ruyck, Jérôme ; Orian-Rousseau, Véronique ; Le Bourhis, Xuefen ; Toillon, Robert-Alain. Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells. In: Journal of experimental & clinical cancer research, Vol. 41, no. 1, p. 110 [1-21] (2022). doi:10.1186/s13046-022-02314-4.
2022
Lan, Junjie ; Cadassou, Octavia ; Corbet, Cyril ; Riant, Olivier ; Feron, Olivier. Discovery of Mitochondrial Complex I Inhibitors as Anticancer and Radiosensitizer Drugs Based on Compensatory Stimulation of Lactate Release. In: Cancers, Vol. 14, no. 21, p. 5454 [1-15] (2022). doi:10.3390/cancers14215454.
2022
Thabault, Léopold ; Brustenga, Chiara ; Savoyen, Perrine ; Van Gysel, Mégane ; Wouters, Johan ; Sonveaux, Pierre ; Frédérick, Raphaël ; Liberelle, Maxime. Discovery of small molecules interacting at lactate dehydrogenases tetrameric interface using a biophysical screening cascade.. In: European journal of medicinal chemistry, Vol. 230, p. 114102 [1-10] (2022). doi:10.1016/j.ejmech.2022.114102.
2022
d'Hose, Donatienne ; Mathieu, Barbara ; Mignion, Lionel ; Hardy, Micael ; Ouari, Olivier ; Jordan, Bénédicte ; Sonveaux, Pierre ; Gallez, Bernard. EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells.. In: Molecules (Basel, Switzerland), Vol. 27, no.18, p. 5872 (2022). doi:10.3390/molecules27185872.
2022
Sancho, Patricia ; Feron, Olivier. Editorial: Insights in pharmacology of anti-cancer drugs: 2021.. In: Frontiers in pharmacology, Vol. 13, p. 1062640 [1-2] (2022). doi:10.3389/fphar.2022.1062640.
2022
Pisapia, Pasquale ; Li, Zhi ; Corbet, Cyril. Editorial: The effect of anti-cancer drug therapies in the treatment of lung cancer. In: Frontiers in Oncology, Vol. 12, no.1, p. 1 (2022). doi:10.3389/fonc.2022.1035245.
2022
Sambon, Pauline ; Sellimi, Amina ; Kozyreff, Alexandra ; Gheysens, Olivier ; Pothen, Lucie ; Yildiz, Halil ; Van Pesch, Vincent. Epidemiology, clinical presentation, treatment, and outcome of neurosarcoidosis: A mono-centric retrospective study and literature review.. In: Frontiers in neurology, Vol. 13, p. 970168 (2022). doi:10.3389/fneur.2022.970168.
2022
Buyse, Chloe ; Joudiou, Nicolas ; Warscotte, Aude ; Richiardone, Elena ; Mignion, Lionel ; Corbet, Cyril ; Gallez, Bernard. Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification.. In: Metabolites, Vol. 12, no.6, p. 12pp (2022). doi:10.3390/metabo12060557.
2022
Kemps, Hannelore ; Dessy, Chantal ; Dumas, Laurent ; Sonveaux, Pierre ; Alders, Lotte ; Van Broekhoven, Jana ; Perez Font, Lena ; Lambrichts, Sara ; Foulquier, Sebastien ; Hendrix, Sven ; Brone, Bert ; Lemmens, Robin ; Bronckaers, Annelies. Extremely low frequency electromagnetic stimulation reduces ischemic stroke volume by improving central collateral blood flow. In: Journal of cerebral blood flow and metabolism, Vol. 42, no. 6, p. 979-996 (2022). doi:10.1177/0271678X221084410.
2022
Ward, Bradley ; Yombi, Jean Cyr ; Balligand, Jean-Luc ; Cani, Patrice D. ; Collet, Jean-François ; De Greef, Julien ; Dewulf, Joseph P. ; Gatto, Laurent ; Haufroid, Vincent ; Jodogne, Sébastien ; Kabamba-Mukadi, Benoît ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Elens, Laure ; Belkhir, Leïla. HYGIEIA: HYpothesizing the Genesis of Infectious Diseases and Epidemics through an Integrated Systems Biology Approach. In: Viruses, Vol. 14, no. 7, p. 1373 [1-17] (2022). doi:10.3390/v14071373.
2022
Brilot, Sarah ; Calvo Lasso De La Vega, Esther ; Michaux, Christian ; Belkhir, Leïla ; Pothen, Lucie. Hépatite fulminante compliquée d’un syndrome hémophagocytaire réactionnel chez un patient immunocompétent : deux manifestations rares d’une infection à Herpes simplex virus 1. In: Louvain médical, Vol. 141, no.9-10, p. 496-501 (2022).
2022
Catanzaro, Elena ; Feron, Olivier ; Skirtach, André G ; Krysko, Dmitri V. Immunogenic Cell Death and Role of Nanomaterials Serving as Therapeutic Vaccine for Personalized Cancer Immunotherapy.. In: Frontiers in immunology, Vol. 13, p. 925290 [1-18] (2022). doi:10.3389/fimmu.2022.925290.
2022
Dechamps, Mélanie ; De Poortere, Julien ; Martin, Manon ; Gatto, Laurent ; Daumerie, Aurélie ; Bouzin, Caroline ; Octave, Marie ; Ginion, Audrey ; Robaux, Valentine ; Pirotton, Laurence ; Bodart, Julie ; Gérard, Ludovic ; Montiel, Virginie ; Campion, Alessandro ; Gruson, Damien ; Van Dievoet, Marie-Astrid ; Douxfils, Jonathan ; Haguet, Hélène ; Morimont, Laure ; Derive, Marc ; Jolly, Lucie ; Bertrand, Luc ; Dumoutier, Laure ; Castanares Zapatero, Diego ; Laterre, Pierre-François ; Horman, Sandrine ; Beauloye, Christophe. Inflammation-Induced Coagulopathy Substantially Differs Between COVID-19 and Septic Shock: A Prospective Observational Study.. In: Frontiers in medicine, Vol. 8, p. 780750 [1-14] (2022). doi:10.3389/fmed.2021.780750.
2022
De Miranda Capeloa, Tania Isabel ; Van de Velde, Justine ; d'Hose, Donatienne ; Lipari, Sara ; Derouane, Françoise ; Hamelin, Loïc ; Bedin, Marie ; Vazeille, Thibaut ; Duhoux, François ; Murphy, Michael P ; Porporato, Paolo E ; Gallez, Bernard ; Sonveaux, Pierre. Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice.. In: Cancers, Vol. 14, no. 19, p. 4918 [1-20] (2022). doi:10.3390/cancers14194918.
2022
Van de Gucht, Melissa ; Dufait, Inès ; Kerkhove, Lisa ; Corbet, Cyril ; de Mey, Sven ; Jiang, Heng ; Law, Ka Lun ; Gevaert, Thierry ; Feron, Olivier ; De Ridder, Mark. Inhibition of Phosphoglycerate Dehydrogenase Radiosensitizes Human Colorectal Cancer Cells under Hypoxic Conditions. In: Cancers, Vol. 14, no. 20, p. 5060 [1-17] (2022). doi:10.3390/cancers14205060.
2022
Johanns, Manuel ; Corbet, Cyril ; Jacobs, Roxane ; Drappier, Melissa ; Bommer, Guido ; Herinckx, Gaëtan ; Vertommen, Didier ; Tajeddine, Nicolas ; Young, David ; Messens, Joris ; Feron, Olivier ; Steinberg, Gregory R ; Hue, Louis ; Rider, Mark H.. Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators.. In: The Biochemical journal, Vol. 479, no. 12, p. 1317-1336 (2022). doi:10.1042/BCJ20220170.
2022
Yildiz, Halil ; Pothen, Lucie (co-first author) ; Lefebvre, Chantal ; De Greef, Julien ; Belkhir, Leïla ; Vincent, Anne ; Roodhans, Fabien ; Balligand, Jean-Luc ; Yombi, Jean Cyr ; Hainaut, Philippe. Innovations 2021 en médecine interne et maladies infectieuses. In: Louvain médical, Vol. 141, no.2, p. 103-107 (2022).
2022
Weber DD ; Aminzadeh-Gohari S ; Thapa M ; Redtenbacher AS ; Catalano L ; De Miranda Capeloa, Tania Isabel ; Vazeille, Thibaut ; Emberger M ; Felder TK ; Feichtinger RG ; Koelblinger P ; Dallmann G ; Sonveaux, Pierre ; Lang R ; Kofler B. Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity. In: Cancer & metabolism, Vol. 10, no. 1, p. 12 [1-20] (2022). doi:10.1186/s40170-022-00288-7.
2022
Ippolito, Luigi ; Sonveaux, Pierre ; Chiarugi, Paola. Lactate: unconventional roles of a nutrient along the tumor landscape. In: Trends in Endocrinology and Metabolism, Vol. 33, no. 4, p. 231-235 (2022).
2022
Ferté, Laura ; Cumps, Julien ; Battault, Sylvain ; Esfahani, Hrag ; Balligand, Jean-Luc ; Horman, Sandrine ; Bertrand, Luc ; Beauloye, Christophe ; Marino, Alice. Letter by Ferté, et al. Regarding Article, "Chronic Pressure Overload Induces Cardiac Hypertrophy and Fibrosis via Increases in SGLT1 and IL-18 Gene Expression in Mice".. In: International heart journal, Vol. 63, no. 1, p. 184-186 (2022). doi:10.1536/ihj.21-442.
2022
Richiardone, Elena ; Van den Bossche, Valentin ; Corbet, Cyril. Metabolic Studies in Organoids: Current Applications, Opportunities and Challenges. In: Organoids, Vol. 1, p. 85-105 (2022). doi:10.3390/ organoids1010008 (Accepté/Sous presse).
2022
Van den Bossche, Valentin ; Zaryouh, Hannah ; Vara-Messler, Marianela ; Vignau, Julie ; Machiels, Jean-Pascal ; Wouters, An ; Schmitz, Sandra ; Corbet, Cyril. Microenvironment-driven intratumoral heterogeneity in head and neck cancers: clinical challenges and opportunities for precision medicine.. In: Drug resistance updates, Vol. 60, no. 1, p. 100806 [1-20] (2022). doi:10.1016/j.drup.2022.100806.
2022
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; d'Hose, Donatienne ; canas Rodriguez, Amanda ; Payen, Valery L ; Zampieri, Luca ; Van de Velde, Justine ; Benyahia, Zohra ; Pranzini, Erica ; Vazeille, Thibaut ; Fransolet, Maude ; Bouzin, Caroline ; Brusa, Davide ; Michiels, Carine ; Gallez, Bernard ; Murphy, Michael P ; Porporato, Paolo E ; Sonveaux, Pierre. MitoQ inhibits human breast cancer cell migration, invasion and clonogenicity. In: Cancers, Vol. 14, no. 6, p. 1516 [1-20] (2022). doi:10.3390/cancers14061516.
2022
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; Canas Rodriguez, Amanda ; Payen, Valery L ; Zampieri, Luca ; Pranzini, Erica ; Derouane, Françoise ; Vazeille, Thibaut ; Bouzin, Caroline ; Duhoux, Francois ; Murphy, Michael P. ; Porporato, Paolo E ; Sonveaux, Pierre. MitoQ prevents human breast cancer recurrence and lung metastasis in mice. In: Cancers, Vol. 14, no. 6, p. 1488 [1-13] (2022). doi:10.3390/cancers14061488.
2022
Blackman, Marine ; De Miranda Capeloa, Tania Isabel ; Rondeau, Justin ; Zampieri, Luca ; Benyahia, Zohra ; Van de Velde, Justine ; Fransolet, Maude ; Daskalopoulos, Evangelos-Panagiotis ; Michiels, Carine ; Beauloye, Christophe ; Sonveaux, Pierre. Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells. In: Cancers, Vol. 14, no. 18, p. 4371 [1-24] (2022). doi:10.3390/cancers14184371.
2022
Macchi, Chiara ; Moregola, Annalisa ; Greco, Maria Francesca ; Svecla, Monika ; Bonacina, Fabrizia ; Dhup, Suveera ; Dadhich, Rajesh Kumar ; Audano, Matteo ; Sonveaux, Pierre ; Mauro, Claudio ; Mitro, Nico ; Ruscica, Massimiliano ; Norata, Giuseppe D. Monocarboxylate transporter 1 deficiency impacts CD8 T lymphocytes proliferation and recruitment to adipose tissue during obesity.. In: iScience, Vol. 25, no. 6, p. 104435 [1-26] (2022). doi:10.1016/j.isci.2022.104435.
2022
Montiel, Virginie ; Lobysheva, Irina ; Gérard, Ludovic ; Vermeersch, Marjorie ; Perez-Morga, David ; Castelein, Thomas ; Mesland, Jean-Baptiste ; Hantson, Philippe ; Collienne, Christine ; Gruson, Damien ; Van Dievoet, Marie-Astrid ; Persu, Alexandre ; Beauloye, Christophe ; Dechamps, Mélanie ; Belkhir, Leïla ; Robert, Annie ; Derive, Marc ; Laterre, Pierre-François ; Danser, A H J ; Wittebole, Xavier ; Balligand, Jean-Luc. Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients.. In: EBioMedicine, Vol. 77, p. 103893 [1-18] (2022). doi:10.1016/j.ebiom.2022.103893.
2022
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Camboni, Alessandra ; Feron, Olivier ; Azevedo, Ricardo Bentes ; Andrade Amorim, Christiani. Photodynamic therapy using OR141-loaded nanovesicles for eradication of leukemic cells from ovarian tissue.. In: Photodiagnosis and photodynamic therapy, Vol. 40, no.-, p. 103139 (2022). doi:10.1016/j.pdpdt.2022.103139.
2022
Derouane, Françoise ; van Marcke, Cédric ; Berlière, Martine ; Gerday, Amandine ; Fellah, Latifa ; Leconte, Isabelle ; Van Bockstal, Mieke ; Galant, Christine ; Corbet, Cyril ; Duhoux, François. Predictive Biomarkers of Response to Neoadjuvant Chemotherapy in Breast Cancer: Current and Future Perspectives for Precision Medicine.. In: Cancers, Vol. 14, no. 16, p. 3876 [1-31] (2022). doi:10.3390/cancers14163876.
2022
d'Hose, Donatienne ; Mignion, Lionel ; Hamelin, Loïc ; Sonveaux, Pierre ; Jordan, Bénédicte ; Gallez, Bernard. Statins Alleviate Tumor Hypoxia in Prostate Cancer Models by Decreasing Oxygen Consumption: An Opportunity for Radiosensitization?. In: Biomolecules, Vol. 12, no.10, p. 1418 (2022). doi:10.3390/biom12101418.
2022
Pothen, Lucie ; Verdoy, Roxane ; De Mulder, Delphine ; Esfahani, Hrag ; Farah, Charlotte ; Michel, Lauriane ; Dei Zotti, Flavia ; Bearzatto, Bertrand ; Ambroise, Jérôme ; Bouzin, Caroline ; Dessy, Chantal ; Balligand, Jean-Luc. Sustained Downregulation of Vascular Smooth Muscle Acta2 After Transient Angiotensin II Infusion: A New Model of "Vascular Memory".. In: Frontiers in cardiovascular medicine, Vol. 9, p. 854361 [1-13] (2022). doi:10.3389/fcvm.2022.854361.
2022
Deskeuvre, Marine ; Lan, Junjie ; Dierge, Emeline ; Messens, Joris ; Riant, Olivier ; Corbet, Cyril ; Feron, Olivier ; Frédérick, Raphaël. Targeting cancer cells in acidosis with conjugates between the carnitine palmitoyltransferase 1 inhibitor etomoxir and pH (low) insertion peptides. In: International Journal of Pharmaceutics, Vol. 624, no.1, p. 122041 (2022). doi:10.1016/j.ijpharm.2022.122041.
2022
Cappellesso, Federica ; Orban, Marie-Pauline ; Shirgaonkar, Niranjan ; Berardi, Emanuele ; Serneels, Jens ; Neveu, Marie-Aline ; di Molfetta, Daria ; Piccapane, Francesca ; Caroppo, Rosa ; Debellis, Lucantonio ; Ostyn, Tessa ; Joudiou, Nicolas ; Mignion, Lionel ; Richiardone, Elena ; Jordan, Bénédicte ; Gallez, Bernard ; Corbet, Cyril ; Roskams, Tania ; Dasgupta, Ramanuj ; Tejpar, Sabine ; Di Matteo, Mario ; Taverna, Daniela ; Reshkin, Stephan Joel ; Topal, Baki ; Virga, Federico ; Mazzone, Massimiliano. Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer. In: Nature Cancer, Vol. 3, p. 1464-1483 (2022). doi:10.1038/s43018-022-00470-2.
2022
Delprat, Victor ; Huart, Camille ; Feron, Olivier ; Soncin, Fabrice ; Michiels, Carine. The impact of macrophages on endothelial cells is potentiated by cycling hypoxia: Enhanced tumor inflammation and metastasis.. In: Frontiers in oncology, Vol. 12, p. 961753 [1-14] (2022). doi:10.3389/fonc.2022.961753.
2022
Yelek, Caner ; Mignion, Lionel ; Paquot, Adrien ; Bouzin, Caroline ; Corbet, Cyril ; Muccioli, Giulio ; Cani, Patrice D. ; Jordan, Bénédicte. Tumor Metabolism Is Affected by Obesity in Preclinical Models of Triple-Negative Breast Cancer. In: Cancers, Vol. 14, no. 3, p. 562 [1-16] (2022). doi:10.3390/cancers14030562.
2022
Delcorte, Ophélie ; Craps, Julie ; Mahibullah, Siam ; Spourquet, Catherine ; D'Auria, Ludovic ; Van Der Smissen, Patrick ; Dessy, Chantal ; Marbaix, Etienne ; Mourad, Michel ; Pierreux, Christophe. Two miRNAs enriched in plasma extracellular vesicles are potential biomarkers for thyroid cancer.. In: Endocrine - Related Cancer, Vol. 29, no.7, p. 389-401 (2022). doi:10.1530/ERC-21-0343.
2022
Ippolito, Luigi ; Sonveaux, Pierre ; Chiarugi, Paola. Unconventional roles of lactate along the tumor and immune landscape.. In: Trends in endocrinology and metabolism, Vol. 33, no.4, p. 231-235 (2022). doi:10.1016/j.tem.2022.01.005.
2022
Craps, Julie ; Joris, Virginie ; Baldeschi, Lelio ; Daumerie, Chantal ; Camboni, Alessandra ; Buemi, Antoine ; Lengelé, Benoît ; Behets Wydemans, Catherine ; Boschi, Antonella ; Mourad, Michel ; Many, Marie-Christine ; Dessy, Chantal. miR-199a Downregulation as a Driver of the NOX4/HIF-1α/VEGF-A Pathway in Thyroid and Orbital Adipose Tissues from Graves' Patients.. In: International journal of molecular sciences, Vol. 23, no. 1, p. 153 [1-18] (2022). doi:10.3390/ijms23010153.
2021
Ngo Njembe, Monique T. ; Pachikian, Barbara ; Lobysheva, Irina ; Van Overstraeten, Nancy ; Dejonghe, Louis ; Verstraelen, Eleonore ; Buchet, Marine ; Rasse, Catherine ; Gardin, Cécile ; Mignolet, Eric ; Balligand, Jean-Luc ; Larondelle, Yvan. A Three-Month Consumption of Eggs Enriched With ω-3, ω-5 and ω-7 Polyunsaturated Fatty Acids Significantly Decreases the Waist Circumference of Subjects at Risk of Developing Metabolic Syndrome: A Double-Blind Randomized Controlled Trial. In: Nutrients, Vol. 13, no. 2, p. 663 [1-17] (2021). doi:10.3390/nu13020663.
2021
Soret, Perrine ; Le Dantec, Christelle ; Desvaux, Emiko ; Foulquier, Nathan ; Chassagnol, Bastien ; Hubert, Sandra ; Jamin, Christophe ; Barturen, Guillermo ; Desachy, Guillaume ; Devauchelle-Pensec, Valérie ; Boudjeniba, Cheïma ; Cornec, Divi ; Saraux, Alain ; Jousse-Joulin, Sandrine ; Barbarroja, Nuria ; Rodríguez-Pintó, Ignasi ; De Langhe, Ellen ; Beretta, Lorenzo ; Chizzolini, Carlo ; Kovács, László ; Witte, Torsten ; Bettacchioli, Eléonore ; Buttgereit, Anne ; Makowska, Zuzanna ; Lesche, Ralf ; Borghi, Maria Orietta ; Martin, Javier ; Courtade-Gaiani, Sophie ; Xuereb, Laura ; Guedj, Mickaël ; Moingeon, Philippe ; Alarcón-Riquelme, Marta E ; Laigle, Laurence ; Pers, Jacques-Olivier. A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome., collab. PRECISESADS Clinical Consortium ; PRECISESADS Flow Cytometry Consortium ; Lauwerys, Bernard ; Ducreux, Julie ; Maudoux, Anne-Lise. In: Nature communications, Vol. 12, no.1, p. 3523 [1-18] (2021). doi:10.1038/s41467-021-23472-7.
2021
Dufeys, Cécile ; Daskalopoulos, Evangelos-Panagiotis (co-first author) ; Castanares Zapatero, Diego ; Conway, Simon J. ; Ginion, Audrey ; Bouzin, Caroline ; Ambroise, Jérôme ; Bearzatto, Bertrand ; Gala, Jean-Luc ; Heymans, Stephane ; Papageorgiou, Anna-Pia ; Vinckier, Stefan ; Cumps, Julien ; Balligand, Jean-Luc ; Vanhaverbeke, Maarten ; Sinnaeve, Peter ; Janssens, Stefan ; Bertrand, Luc ; Beauloye, Christophe ; Horman, Sandrine. AMPKα1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism. In: Basic Research in Cardiology, Vol. 116, p. 10 [1-20] (2021). doi:10.1007/s00395-021-00846-y.
2021
Morelle, Johann ; Marechal, Céline ; Yu, Zanzhe ; Debaix, Huguette ; Corre, Tanguy ; Lambie, Mark ; Verduijn, Marion ; Dekker, Friedo ; Bovy, Philippe ; Evenepoel, Pieter ; Bammens, Bert ; Selgas, Rafael ; Bajo, Maria A. ; Coester, Annemieke M. ; Sow-Diallo, Amadou ; Hautem, Nicolas ; Struijk, Dirk G. ; Krediet, Raymond T. ; Balligand, Jean-Luc ; Goffin, Eric ; Crott, Ralph ; Ripoche, Pierre ; Davies, Simon ; Devuyst, Olivier. AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. In: New England Journal of Medicine, Vol. 385, no. 17, p. 1570-1580 (2021). doi:10.1056/nejmoa2034279.
2021
Colson, Arthur ; Sonveaux, Pierre ; Debiève, Frédéric ; Sferruzzi-Perri, Amanda N. Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction. In: Human Reproduction Update, Vol. 27, no. 3, p. 531-569 (2021). doi:10.1093/humupd/dmaa053.
2021
Balligand, Jean-Luc ; Michel, Lauriane. Assembling fats and sugar for cardiac protection. In: European heart journal, Vol. 42, no. 13, p. 4493–4495 (2021). doi:10.1093/eurheartj/ehab606.
2021
Boulanger, Cécile ; Chatzis, Olga ; Nolf, Delphine ; Brichard, Bénédicte ; Lauwerys, Bernard ; Nassogne, Marie-Cécile ; Limaye, Nisha. Atypical phenotype? The answer’s in the genotype: AGS caused by a novel RNASEH2C variant combined with XLA caused by a BTK deficiency.. In: Rheumatology, Vol. 60, no. 7, p. e240-e242 (2021). doi:10.1093/rheumatology/keab051.
2021
Michel, Lauriane ; Balligand, Jean-Luc. Bèta-3-adrenerge receptoragonisten : therapeutisch potentieel bij de behandeling van prediabetes en hartfalen. In: Bloedvaten Hart Longen, Vol. 26, no.4, p. 27-32 (2021).
2021
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Danhaive, Olivier ; Hubinont, Corinne ; Sonveaux, Pierre ; Debieve, Frédéric. COVID-19 during Pregnancy: Clinical and In Vitro Evidence against Placenta Infection at Term by SARS-CoV-2.. In: The American journal of pathology, Vol. 191, no. 9, p. 1610-1623 (2021). doi:10.1016/j.ajpath.2021.05.009.
2021
Maury, Eléonore ; Navez, Benoît ; Brichard, Sonia. Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation.. In: Nature communications, Vol. 12, no. 1, p. 2388 [1-17] (2021). doi:10.1038/s41467-021-22571-9.
2021
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Danhaive, Olivier ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2.. In: The American journal of pathology, Vol. 191, no. 9, p. 1610-1623 (2021). doi:10.1016/j.ajpath.2021.05.009.
2021
Lysy, Philippe ; Absil, Hélène ; Gasser, Emy ; Boughaleb, Hasnae ; Barrea, Thierry ; Moniotte, Stéphane. Combined Algorithm-Based Adaptations of Insulin Dose and Carbohydrate Intake During Exercise in Children With Type 1 Diabetes: Results From the CAR2DIAB Study. In: Frontiers in endocrinology, Vol. 12, p. 658311 [1-8] (2021). doi:10.3389/fendo.2021.658311.
2021
Triaille, Clément ; Durez, Patrick ; Sokolova, Tatiana ; Tilman, Gaëlle ; Méric de Bellefon, Laurent ; Galant, Christine ; Coulie, Pierre G. ; Lauwerys, Bernard ; Limaye, Nisha. Common Transcriptomic Effects of Abatacept and Other DMARDs on Rheumatoid Arthritis Synovial Tissue. In: Frontiers in immunology, Vol. 12, p. 724895 [1-9] (2021). doi:10.3389/fimmu.2021.724895.
2021
De Greef, Julien ; Scohy, Anaïs ; Zech, Francis ; Aboubakar Nana, Frank ; Pilette, Charles ; Gérard, Ludovic ; Pothen, Lucie ; Yildiz, Halil ; Belkhir, Leïla ; Yombi, Jean Cyr. Determinants of IgG antibodies kinetics after severe and critical COVID-19.. In: Journal of medical virology, Vol. 93, no. 9, p. 5416-5424 (2021). doi:10.1002/jmv.27059.
2021
Van Den Brûle, Sybille ; Rappe, Margaux ; Ambroise, Jérôme ; Bouzin, Caroline ; Dessy, Chantal ; Paquot, Adrien ; Muccioli, Giulio ; Lison, Dominique. Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice.. In: Particle and fibre toxicology, Vol. 18, no. 1, p. 7 [1-15] (2021). doi:10.1186/s12989-021-00400-7.
2021
Thabault, Léopold ; Liberelle, Maxime ; Koruza, Katarina ; Yildiz, Esra ; Joudiou, Nicolas ; Messens, Joris ; Brisson, Lucie ; Wouters, Johan ; Sonveaux, Pierre ; Frédérick, Raphaël. Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides. In: Journal of Biological Chemistry, Vol. 296, p. 100422 (2021). doi:10.1016/j.jbc.2021.100422.
2021
Van Regemorter, Elliott ; Joris, Virginie ; Van Regemorter, Victoria ; Marique, Lancelot ; Behets Wydemans, Catherine ; Lengelé, Benoît ; Boschi, Antonella ; Baldeschi, Lelio ; Daumerie, Chantal ; Many, Marie-Christine ; Craps, Julie. Downregulation of Caveolin-1 and Upregulation of Deiodinase 3, Associated with Hypoxia-Inducible Factor-1α Increase, Are Involved in the Oxidative Stress of Graves' Orbital Adipocytes. In: Thyroid, Vol. 31, no. 4, p. 627-637 (2021). doi:10.1089/thy.2020.0238.
2021
Vincenti, Marie ; Farah, Charlotte ; Amedro, Pascal ; Scheuermann, Valerie ; Lacampagne, Alain ; Cazorla, Olivier. Early Myocardial Dysfunction and Benefits of Cardiac Treatment in Young X-Linked Duchenne Muscular Dystrophy Mice.. In: Cardiovascular drugs and therapy, , p. [1-11] (2021). doi:10.1007/s10557-021-07218-7.
2021
Valenti, Maria Teresa ; Mottes, Monica ; Dalle Carbonare, Luca ; Feron, Olivier. Editorial: Bone Metastases.. In: Frontiers in oncology, Vol. 11, p. 741515 (2021). doi:10.3389/fonc.2021.741515.
2021
Martin Corrons, Inès ; Braem, Fred ; Baudet, Lia ; Poncin, William ; Fizaine, Stéphane ; Aboubakar Nana, Frank ; Froidure, Antoine ; Pilette, Charles ; Liistro, Giuseppe ; De Greef, Julien ; Yildiz, Halil ; Pothen, Lucie ; Yombi, Jean Cyr ; Belkhir, Leïla ; Reychler, Gregory. Follow-up of functional exercise capacity in patients with COVID-19: It is improved by telerehabilitation.. In: Respiratory medicine, Vol. 183, p. 106438 [1-5] (2021). doi:10.1016/j.rmed.2021.106438.
2021
Pothen, Lucie ; Yildiz, Halil ; Samnick, Mathilde Mbouck ; Yombi, Jean Cyr. Hydroxychloroquine in the post-COVID-19 era: will this pandemic upset decades of clinical practice?. In: Clinical rheumatology, Vol. 40, no. 4, p. 1649-1657 (2021). doi:10.1007/s10067-020-05572-9.
2021
Guilmot, Antoine ; Maldonado Slootjes, Sofia Ijke ; Sellimi, Amina ; Bronchain, Maroussia ; Hanseeuw, Bernard ; Belkhir, Leïla ; Yombi, Jean Cyr ; De Greef, Julien ; Pothen, Lucie ; Yildiz, Halil ; Duprez, Thierry ; Fillee, Catherine ; Anantharajah, Ahalieyah ; Capes, Antoine ; Hantson, Philippe ; Jacquerye, Philippe ; Raymackers, Jean-Marc ; London, Frédéric ; El Sankari, Souraya ; Ivanoiu, Adrian ; Maggi, Pietro ; Van Pesch, Vincent. Immune-mediated neurological syndromes in SARS-CoV-2-infected patients.. In: Journal of neurology, Vol. 268, no. 3, p. 751-757 (2021). doi:10.1007/s00415-020-10108-x.
2021
Buyse, Chloé ; Joudiou, Nicolas ; Corbet, Cyril ; Feron, Olivier ; Mignion, Lionel ; Flament, Julien ; Gallez, Bernard. Impact of Inhibition of the Mitochondrial Pyruvate Carrier on the Tumor Extracellular pH as Measured by CEST-MRI. In: Cancers, Vol. 13, no.17, p. 4278 (2021). doi:10.3390/cancers13174278.
2021
Poncin, William ; Baudet, Lia ; Reychler, Gregory ; Duprez, Frédéric ; Liistro, Giuseppe ; Belkhir, Leïla ; Pothen, Lucie ; Yildiz, Halil ; Yombi, Jean Cyr ; De Greef, Julien. Impact of an improvised system on preserving oxygen supplies in patients with COVID- 19.. In: Archivos de Bronconeumologia, Vol. 57, p. 77-79 (2021). doi:10.1016/j.arbres.2020.07.019.
2021
Gonçalves, Ana Cristina ; Richiardone, Elena ; Jorge, Joana ; Polónia, Bárbara ; Xavier, Cristina P.R. ; Salaroglio, Iris Chiara ; Riganti, Chiara ; Vasconcelos, M. Helena ; Corbet, Cyril ; Sarmento-Ribeiro, Ana Bela. Impact of cancer metabolism on therapy resistance – Clinical implications. In: Drug Resistance Updates, , p. 100797 (2021). doi:10.1016/j.drup.2021.100797 (Accepté/Sous presse).
2021
Lasswitz, Lisa ; Gunesch, Antonia P. ; Kasten, Martina ; Zapatero-Belinchon, Francisco J. ; Brogden, Graham ; Gerold, Gisa ; Pietschmann, Thomas ; Montiel, Virginie ; Balligand, Jean-Luc ; Facciotti, Federica ; Hirsch, Emilio ; Gausepohl, Thomas ; Elbahesh, Husni ; Rimmelzwaan, Guus F. ; Höfer, Anne ; Kühnel, Mark P. ; Jonigk, Danny ; Eigendorf, Julian ; Tegtbur, Uwe ; Mink, Lena ; Scherr, Michaela ; Illig, Thomas ; Schambach, Axel ; Pfeffer, Tobias J. ; Hilfiker, Andres ; Haverich, Axel ; Hilfiker-Kleiner, Denise. Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease, collab. Ricke-Hoch, Melanie ; Stelling, Elisabeth. In: PLoS One, Vol. 16, no. 8, p. e0255335 [1-24] (2021). doi:10.1371/journal.pone.0255335.
2021
Benyahia, Zohra ; Blackman, Marine ; Hamelin, Loïc ; Zampieri, Luca ; De Miranda Capeloa, Tania Isabel ; Bedin, Marie ; Vazeille, Thibaut ; Schakman, Olivier ; Sonveaux, Pierre. In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment. In: Cancers, Vol. 13, no.3, p. 569 (2021). doi:10.3390/cancers13030569.
2021
Gérard, Ludovic ; Lecocq, Marylène ; Bouzin, Caroline ; Hoton, Delphine ; Schmit, Gregory ; Pinto Pereira, Joao ; Montiel, Virginie ; Plante-Bordeneuve, Thomas ; Laterre, Pierre-François ; Pilette, Charles. Increased Angiotensin-Converting Enzyme 2 and Loss of Alveolar Type II Cells in COVID-19-related Acute Respiratory Distress Syndrome.. In: American journal of respiratory and critical care medicine, Vol. 204, no.9, p. 1024-1034 (2021). doi:10.1164/rccm.202012-4461OC.
2021
Froidure, Antoine ; Mahsouli, Amin ; Liistro, Giuseppe ; De Greef, Julien ; Belkhir, Leïla ; Gerard, Ludovic ; Bertrand, Aurélie ; Koenig, Sandra ; Pothen, Lucie ; Yildiz, Halil ; Mwenge, Gimbada Benny ; Aboubakar Nana, Frank ; Gohy, Sophie ; Pilette, Charles ; Reychler, Gregory ; Coche, Emmanuel ; Yombi, Jean Cyr ; Ghaye, Benoît. Integrative respiratory follow-up of severe COVID-19 reveals common functional and lung imaging sequelae.. In: Respiratory medicine, Vol. 181, p. 106383 [1-6] (2021). doi:10.1016/j.rmed.2021.106383.
2021
Michel, Lauriane ; Balligand, Jean-Luc. Les agonistes des récepteurs adrénergiques Beta-3 : potentiel thérapeutique dans le traitement du prédiabète et de l'insuffisance cardiaque. In: Vaisseaux cœur poumons, Vol. 26, no.4, p. 27-32 (2021).
2021
Collin, Amandine ; Lecocq, Marylène ; Detry, Bruno ; Carlier, François ; Bouzin, Caroline ; De Sany, Philippe ; Hoton, Delphine ; Verleden, Stijn ; Froidure, Antoine ; Pilette, Charles ; Gohy, Sophie. Loss of ciliated cells and altered airway epithelial integrity in cystic fibrosis.. In: Journal of cystic fibrosis, Vol. 20, no. 6, p. e129-e139 (2021). doi:10.1016/j.jcf.2021.09.019.
2021
Virga, Federico ; Cappellesso, Federica ; Stijlemans, Benoit ; Henze, Anne-Theres ; Trotta, Rosa ; Van Audenaerde, Jonas ; Mirchandani, Ananda S. ; Sanchez-Garcia, Manuel A. ; Vandewalle, Jolien ; Orso, Francesca ; Riera-Domingo, Carla ; Griffa, Alberto ; Ivan, Cristina ; Smits, Evelien ; Laoui, Damya ; Martelli, Fabio ; Langouche, Lies ; Van den Berghe, Greet ; Feron, Olivier ; Ghesquière, Bart ; Prenen, Hans ; Libert, Claude ; Walmsley, Sarah R. ; Corbet, Cyril ; Van Ginderachter, Jo A. ; Ivan, Mircea ; Taverna, Daniela ; Mazzone, Massimiliano. Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation. In: Science Advances, Vol. 7, no.19, p. eabf0466 (2021). doi:10.1126/sciadv.abf0466.
2021
Zampieri, Luca ; Da Silva Almeida, Ana Catarina ; Rondeau, Justin ; Sonveaux, Pierre. Mitochondrial Transfer in Cancer: A Comprehensive Review. In: International Journal of Molecular Sciences, Vol. 22, no.6, p. 3245 (2021). doi:10.3390/ijms22063245.
2021
Zampieri, Luca ; Sboarina, Martina ; Cacace, Andrea ; Grasso, Debora ; Thabault, Léopold ; Hamelin, Loïc ; Vazeille, Thibaut ; Dumon, Elodie ; Rossignol, Rodrigue ; Frédérick, Raphaël ; Sonveaux, Etienne ; Lefranc, Florence ; Sonveaux, Pierre. Olaparib is a mitochondrial Complex I inhibitor that kills temozolomide-resistant human glioblastoma cells. In: International Journal of Molecular Sciences, Vol. 22, no.11938, p. 17 (2021). doi:10.3390/ijms222111938.
2021
Hepp, Michael ; Wérion, Alexis ; De Greef, Axel ; de Ville de Goyet, Christine ; de Bournonville, Marc ; Behets Wydemans, Catherine ; Lengelé, Benoît ; Daumerie, Chantal ; Mourad, Michel ; Ludgate, Marian ; Many, Marie-Christine ; Joris, Virginie ; Craps, Julie. Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto's Thyroiditis.. In: International journal of molecular sciences, Vol. 22, no. 8, p. 3806 [1-17] (2021). doi:10.3390/ijms22083806.
2021
Dierge, Emeline ; Debock, Elena ; Guilbaud, Céline ; Corbet, Cyril ; Mignolet, Eric ; Mignard, Louise ; Bastien, Estelle ; Dessy, Chantal ; Larondelle, Yvan ; Feron, Olivier. Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects. In: Cell Metabolism, Vol. S1550-4131, no.21, p. 00233-3 (2021). doi:10.1016/j.cmet.2021.05.016.
2021
Ughetto, Stefano ; Migliore, Cristina ; Pietrantonio, Filippo ; Apicella, Maria ; Petrelli, Annalisa ; D'Errico, Laura ; Durando, Stefania ; Moya-Rull, Daniel ; Bellomo, Sara E ; Rizzolio, Sabrina ; De Miranda Capeloa, Tania Isabel ; Ribisi, Salvatore ; Degiuli, Maurizio ; Reddavid, Rossella ; Rapa, Ida ; Fumagalli, Uberto ; De Pascale, Stefano ; Ribero, Dario ; Baronchelli, Carla ; Sgroi, Giovanni ; Rausa, Emanuele ; Baiocchi, Gian Luca ; Molfino, Sarah ; Manenti, Stefania ; Bencivenga, Maria ; Sacco, Michele ; Castelli, Claudia ; Siena, Salvatore ; Sartore-Bianchi, Andrea ; Tosi, Federica ; Morano, Federica ; Raimondi, Alessandra ; Prisciandaro, Michele ; Gloghini, Annunziata ; Marsoni, Silvia ; Sottile, Antonino ; Sarotto, Ivana ; Sapino, Anna ; Marchiò, Caterina ; Cassoni, Paola ; Guarrera, Simonetta ; Corso, Simona ; Giordano, Silvia. Personalized therapeutic strategies in HER2-driven gastric cancer.. In: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, Vol. 24, no.4, p. 897-912 (2021). doi:10.1007/s10120-021-01165-w.
2021
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Azevedo, Ricardo Bentes ; Feron, Olivier ; Amorim, Christiani A. Photodynamic cancer therapy using liposomes as an advanced vesicular photosensitizer delivery system.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 339, p. 75-90 (2021). doi:10.1016/j.jconrel.2021.09.024 (Accepté/Sous presse).
2021
Yildiz, Halil ; Castanares Zapatero, Diego ; Hannesse, Colin ; Vandermeersch, Denis ; Pothen, Lucie ; Yombi, Jean Cyr. Prospective validation and comparison of COVID-GRAM, NEWS2, 4C mortality score, CURB-65 for the prediction of critical illness in COVID-19 patients.. In: Infectious diseases, Vol. 53, no.8, p. 640-642 (2021). doi:10.1080/23744235.2021.1896777.
2021
Vermonden, Perrine ; Vancoppenolle, Matthias ; Dierge, Emeline ; Mignolet, Eric ; Cuvelier, Géraldine ; Knoops, Bernard ; Page, Melissa ; Debier, Cathy ; Feron, Olivier ; Larondelle, Yvan. Punicic Acid Triggers Ferroptotic Cell Death in Carcinoma Cells. In: Nutrients, Vol. 13, no. 8, p. 2751 [1-16] (2021). doi:10.3390/nu13082751.
2021
Humby, Frances ; Durez, Patrick ; Buch, Maya H ; Lewis, Myles J ; Rizvi, Hasan ; Rivellese, Felice ; Nerviani, Alessandra ; Giorli, Giovanni ; Mahto, Arti ; Montecucco, Carlomaurizio ; Lauwerys, Bernard ; Ng, Nora ; Ho, Pauline ; Bombardieri, Michele ; Romão, Vasco C ; Verschueren, Patrick ; Kelly, Stephen ; Sainaghi, Pier Paolo ; Gendi, Nagui ; Dasgupta, Bhaskar ; Cauli, Alberto ; Reynolds, Piero ; Cañete, Juan D ; Moots, Robert ; Taylor, Peter C ; Edwards, Christopher J ; Isaacs, John ; Sasieni, Peter ; Choy, Ernest ; Pitzalis, Costantino. Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial., collab. R4RA collaborative group. In: Lancet, Vol. 397, no. 10271, p. 305-317 (2021). doi:10.1016/S0140-6736(20)32341-2.
2021
van Marcke, Cédric ; Honoré, Natasha (co-first author) ; van der Elst, Athénaïs (co-first author) ; Beyaert, Simon ; Derouane, Françoise ; Dumont, Caroline ; Aboubakar Nana, Frank ; Baurain, Jean-François ; Borbath, Ivan ; Collard, Philippe ; Cornelis, Frank ; De Cuyper, Astrid ; Duhoux, Francois ; Filleul, Bertrand ; Galot, Rachel ; Gizzi, Marco ; Mazzeo, Filomena ; Pieters, Thierry ; Seront, Emmanuel ; Sinapi, Isabelle ; Van Den Eynde, Marc ; Whenham, Nicolas ; Yombi, Jean Cyr ; Scohy, Anaïs ; van Maanen, Aline ; Machiels, Jean-Pascal. Safety of systemic anti-cancer treatment in oncology patients with non-severe COVID-19: a cohort study.. In: BMC cancer, Vol. 21, no.1, p. 578 [1-12] (2021). doi:10.1186/s12885-021-08349-8.
2021
Vander Linden, Catherine ; Corbet, Cyril ; Bastien, Estelle ; Martherus, Ruben ; Guilbaud, Céline ; Petit, Laurenne ; Wauthier, Loris ; Loriot, Axelle ; De Smet, Charles ; Feron, Olivier. Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition. In: Cell Reports, Vol. 35, no.9, p. 109202 (2021). doi:10.1016/j.celrep.2021.109202.
2021
Yildiz, Halil ; Castanares Zapatero, Diego ; Pierman, Guillaume ; Pothen, Lucie ; De Greef, Julien ; Aboubakar Nana, Frank ; Rodriguez-Villalobos, Hector ; Belkhir, Leïla ; Yombi, Jean Cyr. Validation of Neutrophil-to-Lymphocyte Ratio Cut-off Value Associated with High In-Hospital Mortality in COVID-19 Patients.. In: International journal of general medicine, Vol. 14, p. 5111-5117 (2021). doi:10.2147/IJGM.S326666.
2021
Balligand, Jean-Luc ; Bertrand, Luc. You “heart” what you eat!. In: Cardiovascular research, Vol. 117, no. 11, p. 2294-2296 (2021). doi:10.1093/cvr/cvab118.
2023
Aubert, Léo ; Özkan, Kübra ; Guilbaud, Céline ; Bruno, Philippine ; Srhir, Sarah ; Feron, Olivier. Deciphering the interplay between circadian clock and tumor metabolism to optimize anticancer chronotherapies. BACR (Belgian Association for Cancer Research) Annual Meeting (Bruxelles (Belgium), 27/10/2023).
2023
Aubert, Léo ; Özkan, Kübra ; Srhir, Sarah ; Bruno, Philippine ; Guilbaud, Céline ; Feron, Olivier. Deciphering the interplay between circadian rhythms and metabolic preferences in colorectal cancer cells and 3D spheroids.. Gordon Research Seminar: "Biological Timekeepers: Models, Mechanisms and Physiology" (Bates College, du 17/06/2023 au 18/06/2023).
2023
Aubert, Léo ; Özkan, Kübra ; Srhir, Sarah ; Bruno, Philippine ; Guilbaud, Céline ; Feron, Olivier. Deciphering the interplay between circadian rhythms and metabolic preferences in colorectal cancer cells and 3D spheroids.. Gordon Research Conference "Clocks Across the Phylogenetic Tree, from Single Cell to Humans" (Bates College, du 18/06/2023 au 23/06/2023).
2022
Sonveaux, Pierre. Metastasis prevention (in breast cancer) with superoxide scavengers. Radiotherapy Online-Seminar Series of the University of Maastricht/MUMC/Maastro (Maastricht, The Netherlands, 11/03/2022).
2022
Triaille, Clément ; Sokolova, Tatiana ; De Montjoye, Stéphanie ; Nzeusseu Toukap, Adrien ; Meric de Bellefon, Laurent ; Loriot, Axelle ; Lauwerys, Bernard ; Durez, Patrick ; Limaye, Nisha. POS0448 Synovial transcriptomic profiles correlate with disease activity in early untreated rheumatoid arthritis. EULAR 2022 European Congress of Rheumatology ((Denmark) Copenhagen, du 01/06/2022 au 04/06/2022). In: Annals of the rheumatic diseases, Vol. 81, no. Suppl 1, p. 478 (2022). doi:10.1136/annrheumdis-2022-eular.4957.
2022
Grasso, Debora ; Sonveaux, Pierre. Preservation of mitochondrial integrity participates in radioresistance in head and neck mouse cancer models. ESTRO 2022 (Copenhaguen, Denmark, du 06/05/2022 au 10/05/2022).
2022
Sonveaux, Pierre. Towards the prevention of local recurrence and distant metastases in breast cancer. Meeting Series of the Royal Society of Chemistry (RSC) - Belgian Section (Louvain-la-Neuve (online), 19/05/2022).
2021
Sonveaux, Pierre ; Frédérick, Raphaël. Identification and development of LDH inhibitors to treat cancer. Seminar Series of the European Institute of Chemistry and Biology (IECB) (11/06/2021).
2021
Sonveaux, Pierre. Lactate signals pseudohypoxia in cancer. EMBO workshop: lactate: unconventional roles of a nutrient along tumor landscape (Florence, Italy, du 21/06/2021 au 23/06/2021).
2021
Dumas, Laurent ; Metzinger, Thomas ; Marchand,Dorothée ; Esfahani, Hrag ; Kurbanova, S ; Maistriaux, Louis ; Bastien, Estelle ; Daskalopoulos, Evangelos-Panagiotis ; Horman, Sandrine ; Dessy, Chantal. MiR-199a is differentially regulated during physiological and pathological cardiac hypertrophy. HFA Winter Meeting 2021 (On line, du 20/01/2021 au 21/01/2021). In: European Journal of Heart Failure, Vol. 23, no.Suppl 1, p. 9 (2021). doi:10.1002/ejhf.2100.
2021
Sonveaux, Pierre. Mitochondrial superoxide at the core of the metastatic process of cancers. Journée Mitochondrie Métabolisme et Cancer (Angers University, France, 17/11/2021).
2021
Sonveaux, Pierre. Opening lecture: preventing cancer metastasis with superoxide scavengers. 9th International Symposium of Gunma University for Advanced Research: Breakthroughs in Cancer Metabolism and Technological Pers (Gunma, Japan, 25/02/2021).
2021
De Miranda Capeloa, Tania Isabel ; Paolo E Porporato ; Sonveaux, Pierre. Preventing cancer metastasis with specific inhibitors of mitochondrial superoxide. 33rd AICC Annual conference: International Meeting on Cancer Metabolism (Turin, Italy, du 22/11/2021 au 25/11/2021).
2021
Sonveaux, Pierre. Preventing cancer metastasis with superoxide scavengers. 4th Metabolism & Cancer conference (Bordeaux, France, du 27/05/2021 au 29/05/2021).
2021
Vanderputten, Marie ; Aboubakar Nana, Frank ; Bouzin, Caroline ; Hoton, Delphine ; Stanciu Pop, Claudia Maria ; Lecocq, Marylène ; Ambroise, Jérôme ; Pilette, Charles ; Ocak, Sebahat. Prognostic Significance of IgA+ B Cells in Non-Small Cell Lung Cancer [P72.10]. 2020 World Conference on Lung Cancer (Virtual, du 28/01/2021 au 31/01/2021). In: Journal of Thoracic Oncology, Vol. 16, no.3, p. S569 (2021). doi:10.1016/j.jtho.2021.01.1028.
2021
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Hubinont, Corinne ; Danhaive, Olivier ; Sonveaux, Pierre ; Debieve, Frédéric. Risk of COVID-19 maternofetal transmission at term: new evidence against placental infection by SARS-CoV-2. IFPA Annual Meeting 2021 (Virtual, du 30/08/2021 au 02/09/2021).
2021
Colson, Arthur ; Lambert, Isaline ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debieve, Frédéric. Use of the Hypoxia-Inducible Factor (HIF)-2α Inhibitor PT2385 in Placental Dysfunction: New Intervention Addressing Fetal Growth Restriction and Preeclampsia. 68th annual meeting of the Society for Reproductive Investigation (Boston, du 06/07/2021 au 09/07/2021).
2023
Van den bossche, Valentin. Microenvironment-mediated lipid metabolism reprogramming upon anti-EGFR therapy resistance in head and neck squamous cell carcinoma , prom. : Corbet, Cyril ; Schmitz, Sandra ; Feron, Olivier, 15/11/2023.
2023
Blackman, Marine. Mitochondrial protein COX7b is responsible for brain-specific metastasis of human breast cancer cells, prom. : Sonveaux, Pierre, 13/03/2023.
2023
Colson, Arthur. Targeting the hypoxia-inducible factor 2α in placental dysfunction : towards new treatments for preeclampsia and fetal growth restriction, prom. : Debiève, Frédéric ; Sonveaux, Pierre, 23/11/2023.
2023
Derouane, Françoise. Towards the identification of new biomarkers to better predict response to neoadjuvant chemotherapy in breast cancers, prom. : Duhoux, François ; Corbet, Cyril, 27/11/2023.
2022
Zampieri, Luca. Targeting mitophagy to overcome chemoresistance in ovarian and brain cancers, prom. : Sonveaux, Pierre, 13/01/2022.
2022
Vander Linden, Catherine. Towards a more rational use of metabolism-targeting drugs as anticancer treatments, prom. : Feron, Olivier ; Corbet, Cyril, 07/02/2022.
2022
Dierge, Emeline. Towards therapeutic exploitation of tumor addiction to fatty acids under acidosis, prom. : Larondelle, Yvan ; Feron, Olivier, 07/01/2022.
2022
Pothen, Lucie. Vascular memory, from old concepts to a new model : sustained down-regulation of alpha-Smooth Muscle Actin induced by Angiotensin II , prom. : Balligand, Jean-Luc, 31/08/2022.
2023
Bordeleau, Marie-ève ; Sauvageau, Guy ; Roux, Philippe P. ; Lavallée, Vincent-Philippe ; Métois, Arnaud ; Theret, Louis ; Aubert, Léo. Agents for the treatment of Acute Myeloid Leukemia. .
2021
Sonveaux, Pierre ; De Miranda Capeloa, Tania Isabel. Molecular signature for assessing the responsiveness of cancer to mitochondria-targeted antioxidants. .
2021
Sonveaux, Pierre ; Thabault, Léopold ; Liberelle, Maxime ; Frédérick, Raphaël. Polypeptide inhibitors of lactate dehydrogenase activity for use in cancer therapy. Déposé. .
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