Selection de publications

FATH

Joris V, Gomez EL, Menchi L, Lobysheva I, Di Mauro V, Esfahani H, Condorelli G, Balligand JL, Catalucci D, Dessy C. MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium. (2018) Arterioscler Thromb Vasc Biol. pii: ATVBAHA.118.311145. doi: 10.1161/ATVBAHA.118.311145.

Duisit J, Amiel H, Wüthrich T, Taddeo A, Dedriche A, Destoop V, Pardoen T, Bouzin C, Joris V, Magee D, Vögelin E, Harriman D, Dessy C, Orlando G, Behets C, Rieben R, Gianello P, Lengelé B. Perfusion-decellularization of human ear grafts enables ECM-based scaffolds for auricular vascularized composite tissue engineering. (2018) Acta Biomater.  pii: S1742-7061(18)30199-5. doi: 10.1016/j.actbio.2018.04.009.

Duisit J, Maistriaux L, Taddeo A, Orlando G, Joris V, Coche E, Behets C, Lerut J, Dessy C, Cossu G, Vögelin E, Rieben R, Gianello P, Lengelé B. Bioengineering a Human Face Graft: The Matrix of Identity. (2017) Ann Surg. ;266(5):754-764.

Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM. Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction. (2017) Gut. pii: gutjnl-2016-313316.

Vanhoutte L, Guilbaud C, Martherus R, Bouzin C, Gallez B, Dessy C, Balligand JL, Moniotte S, Feron O. MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression. (2017) Sci Rep.;7:43951.

Dogné S, Rath G, Jouret F, Caron N, Dessy C, Flamion B. Hyaluronidase 1 deficiency preserves endothelial function and glycocalyx integrity in early streptozotocin-induced diabetes. (2016) Diabetes.

Romero M, Jimenez R, Toral M, Leon-Gomez E, Gomez-Guzman M, Sanchez M, Zarzuelo MJ, Rodriguez-Gomez I, Rath G, Tamargo J, Perez-Vizcaino F, Dessy C, Duarte J. Vascular and central activation of Peroxisome Proliferator-Activated Receptor-β attenuates angiotensin II-induced hypertension. Role of RGS-5. (2016) J Pharmacol Exp Ther.

Catry E, Neyrinck AM, Lobysheva I, Pachikian BD, Van Hul M, Cani PD, Dessy C, Delzenne NM. Nutritional depletion in n-3 PUFA in apoE knock-out mice: a new model of endothelial dysfunction associated with fatty liver disease. (2016) Mol Nutr Food Res.

Romero M, Leon-Gomez E, Lobysheva I, Rath G, Dogné JM, Feron O, Dessy C. Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis. (2016) PLoS One.

Madlala HP, Metzinger T, van Heerden FR, Musabayane CT, Mubagwa K, Dessy C. Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects. (2016) PLoS One.

Pinto A, Mace Y, Drouet F, Bony E, Boidot R, Draoui N, Lobysheva I, Corbet C, Polet F, Martherus R, Deraedt Q, Rodríguez J, Lamy C, Schicke O, Delvaux D, Louis C, Kiss R, Kriegsheim AV, Dessy C, Elias B, Quetin-Leclercq J, Riant O, Feron O. A new ER-specific photosensitizer unravels 1O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT. (2015) Oncogene.

Horckmans M, Esfahani H, Beauloye C, Clouet S, di Pietrantonio L, Robaye B, Balligand JL, Boeynaems JM, Dessy C, Communi D. Loss of mouse P2Y4 nucleotide receptor protects against myocardial infarction through endothelin-1 downregulation. (2015) J Immunol.

Martinsen A, Dessy C, Morel N. Regulation of calcium channels in smooth muscle: new insights into the role of myosin light chain kinase. (2014) Channels (Austin).

Balteau M, Van Steenbergen A, Timmermans AD, Dessy C, Behets-Wydemans G, Tajeddine N, Castanares-Zapatero D, Gilon P, Vanoverschelde JL, Horman S, Hue L, Bertrand L, Beauloye C. AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes. (2014) Am J Physiol Heart Circ Physiol.

Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL. Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase. (2014) Circulation.

Martinsen A, Schakman O, Yerna X, Dessy C, Morel N. Myosin light chain kinase controls voltage-dependent calcium channels in vascular smooth muscle. (2014) Pflugers Arch.

Montiel V, Leon Gomez E, Bouzin C, Esfahani H, Romero Perez M, Lobysheva I, Devuyst O, Dessy C, Balligand JL. Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation. (2014) Pflugers Arch.

Martinsen A, Yerna X, Rath G, Gomez EL, Dessy C, Morel N. Different effect of Rho kinase inhibition on calcium signaling in rat isolated large and small arteries. (2012) J Vasc Res.

Horckmans M, Léon-Gómez E, Robaye B, Balligand JL, Boeynaems JM, Dessy C, Communi D. Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise. (2012) Am J Physiol Heart Circ Physiol. 1;303(7).

Rath G, Saliez J, Behets G, Romero-Perez M, Leon-Gomez E, Bouzin C, Vriens J, Nilius B, Feron O, Dessy C. Vascular hypoxic preconditioning relies on TRPV4-dependent calcium influx and proper intercellular gap junctions communication. (2012) Arterioscler Thromb Vasc Biol. 32(9).

Li Y, Wang H, Tarus B, Perez MR, Morellato L, Henry E, Berka V, Tsai AL, Ramassamy B, Dhimane H, Dessy C, Tauc P, Boucher JL, Deprez E, Slama-Schwok A. Rational design of a fluorescent NADPH derivative imaging constitutive nitric-oxide synthases upon two-photon excitation. (2012) Proc Natl Acad Sci U S A. 31;109(31).

Rath G, Balligand JL, Dessy C. Vasodilatory mechanisms of beta receptor blockade. (2012)

Curr Hypertens Rep. 14(4):310-7.

Horckmans M, Robaye B, Léon-Gόmez E, Lantz N, Unger P, Dol-Gleizes F, Clouet S, Cammarata D, Schaeffer P, Savi P, Gachet C, Balligand JL, Dessy C, Boeynaems JM, Communi D. P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development. (2012) Angiogenesis. 15(3):349-60.

Boidot R, Végran F, Meulle A, Le Breton A, Dessy C, Sonveaux P, Lizard-Nacol S, Feron O. Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors. (2012) Cancer Res. 72(4):939-48.

Lobysheva I, Rath G, Sekkali B, Bouzin C, Feron O, Gallez B, Dessy C, Balligand JL. Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells. (2011) Arterioscler Thromb Vasc Biol. 31(9):2098-105.

Verrax J, Defresne F, Lair F, Vandermeulen G, Rath G, Dessy C, Préat V, Feron O. Delivery of soluble VEGF receptor 1 (sFlt1) by gene electrotransfer as a new antiangiogenic cancer therapy. (2011) Mol Pharm. 8(3):701-8.

Banquet S, Delannoy E, Agouni A, Dessy C, Lacomme S, Hubert F, Richard V, Muller B, Leblais V. Role of G(i/o)-Src kinase-PI3K/Akt pathway and caveolin-1 in β-adrenoceptor coupling to endothelial NO synthase in mouse pulmonary artery. (2011) Cell Signal. 23(7):1136-43.

Sorrentino SA, Doerries C, Manes C, Speer T, Dessy C, Lobysheva I, Mohmand W, Akbar R, Bahlmann F, Besler C, Schaefer A, Hilfiker-Kleiner D, Lüscher TF, Balligand JL, Drexler H, Landmesser U. Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade. (2011) J Am Coll Cardiol. 57(5):601-11.

Dessy C, Balligand JL. Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives. (2010) Adv Pharmacol. 59:135-63.

Dessy C, Feron O, Balligand JL. The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the 'endothelium-derived hyperpolarizing factor'. (2010) Pflugers Arch. 459(6):817-27.

Rath G, Dessy C, Feron O. Caveolae, caveolin and control of vascular tone: nitric oxide (NO) and endothelium derived hyperpolarizing factor (EDHF) regulation. (2009) J Physiol Pharmacol. 60 Suppl 4:105-9.

Decrem Y, Rath G, Blasioli V, Cauchie P, Robert S, Beaufays J, Frère JM, Feron O, Dogné JM, Dessy C, Vanhamme L, Godfroid E. Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis. (2009) J Exp Med. 206(11):2381-95.

Frérart F, Lobysheva I, Gallez B, Dessy C, Feron O. Vascular caveolin deficiency supports the angiogenic effects of nitrite, a major end product of nitric oxide metabolism in tumors. (2009) Mol Cancer Res. (7):1056-63.

Senou M, Costa MJ, Massart C, Thimmesch M, Khalifa C, Poncin S, Boucquey M, Gérard AC, Audinot JN, Dessy C, Ruf J, Feron O, Devuyst O, Guiot Y, Dumont JE, Van Sande J, Many MC. Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice. (2009) Am J Physiol Endocrinol Metab. 297(2):E438-51.

Balligand JL, Feron O, Dessy C. eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues. (2009) Physiol Rev. 89(2):481-534.

Martinive P, Defresne F, Quaghebeur E, Daneau G, Crokart N, Grégoire V, Gallez B, Dessy C, Feron O. Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments. (2009) FEBS J. 276(2):509-18.

Frérart F, Sonveaux P, Rath G, Smoos A, Meqor A, Charlier N, Jordan BF, Saliez J, Noël A, Dessy C, Gallez B, Feron O. The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy. (2008) Clin Cancer Res. 14(9):2768-74.

Desjardins F, Lobysheva I, Pelat M, Gallez B, Feron O, Dessy C, Balligand JL. Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis. (2008) Cardiovasc Res. 79(3):527-36.

Billon A, Lehoux S, Lam Shang Leen L, Laurell H, Filipe C, Benouaich V, Brouchet L, Dessy C, Gourdy P, Gadeau AP, Tedgui A, Balligand JL, Arnal JF. The estrogen effects on endothelial repair and mitogen-activated protein kinase activation are abolished in endothelial nitric-oxide (NO) synthase knockout mice, but not by NO synthase inhibition by N-nitro-L-arginine methyl ester. (2008) Am J Pathol. 172(3):830-8.

Saliez J, Bouzin C, Rath G, Ghisdal P, Desjardins F, Rezzani R, Rodella LF, Vriens J, Nilius B, Feron O, Balligand JL, Dessy C. Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells. (2008) Circulation. 117(8):1065-74.