Publications
Neuro-Differenciation
2021
Baudouin, Charlotte ; Pelosi, Barbara ; Courtoy, Guillaume E ; Achouri, Younes ; Clotman, Frédéric. Generation and characterization of a tamoxifen-inducible Vsx1-CreER line to target V2 interneurons in the mouse developing spinal cord.. In: Genesis: The Journal of Genetics and Development, , p. e23435 (2021). doi:10.1002/dvg.23435 (Accepté/Sous presse).
2020
Gray de Cristoforis, Angelica ; Ferrari, Francesco ; Clotman, Frédéric ; Vogel, Tanja. Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.. In: Molecular Brain, Vol. 13, no.1, p. 85 (2020). doi:10.1186/s13041-020-00623-3.
2020
Romanov, Roman A ; Tretiakov, Evgenii O ; Kastriti, Maria Eleni ; Zupancic, Maja ; Häring, Martin ; Korchynska, Solomiia ; Popadin, Konstantin ; Benevento, Marco ; Rebernik, Patrick ; Lallemend, Francois ; Nishimori, Katsuhiko ; Clotman, Frédéric ; Andrews, William D ; Parnavelas, John G ; Farlik, Matthias ; Bock, Christoph ; Adameyko, Igor ; Hökfelt, Tomas ; Keimpema, Erik ; Harkany, Tibor. Molecular design of hypothalamus development.. In: Nature, Vol. 582, no. 7811, p. 246-252 (2020). doi:10.1038/s41586-020-2266-0 (Accepté/Sous presse).
2020
Toch, Mathilde ; Harris, Audrey ; Schakman, Olivier ; Kondratskaya, Elena ; Boulland, Jean-Luc ; Dauguet, Nicolas ; Debrulle, Stéphanie ; Baudouin, Charlotte ; Hidalgo-Figueroa, Maria ; Gow, Alexander ; Glover, Joel C ; Tissir, Fadel ; Clotman, Frédéric. Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.. In: Scientific reports, Vol. 10, no. 1, p. 996 [1-17] (2020). doi:10.1038/s41598-020-57945-4.
2019
Toch, Mathilde ; Clotman, Frédéric. CBP and p300 coactivators contribute to the maintenance of Isl1 expression by the Onecut transcription factors in embryonic spinal motor neurons.. In: Molecular and Cellular Neuroscience, Vol. 101, p. 103411 (2019). doi:10.1016/j.mcn.2019.103411 (Accepté/Sous presse).
2019
Harris, Audrey ; Masgutova, Gauhar ; Collin, Amandine ; Toch, Mathilde ; Hidalgo-Figueroa, Maria ; Jacob, Benvenuto ; Corcoran, Lynn M. ; Francius, Cédric ; Clotman, Frédéric. Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord. In: Frontiers in Cellular Neuroscience, Vol. 13, no.184, p. 1 (2019). doi:10.3389/fncel.2019.00184.
2019
Masgutova, Gauhar ; Harris, Audrey ; Jacob, Benvenuto ; Corcoran, Lynn M ; Clotman, Frédéric. Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord.. In: Frontiers in Molecular Neuroscience, Vol. 12, p. 263 (2019). doi:10.3389/fnmol.2019.00263.
2019
Debrulle, Stéphanie ; Baudouin, Charlotte ; Hidalgo-Figueroa, Maria ; Pelosi, Barbara ; Francius, Cédric ; Rucchin, Vincent ; Ronellenfitch, Kara ; Chow, Robert L ; Tissir, Fadel ; Lee, Soo-Kyung ; Clotman, Frédéric. Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development.. In: Cellular and Molecular Life Sciences, (2019). doi:10.1007/s00018-019-03408-7 (Accepté/Sous presse).
2018
Clotman, Frédéric ; Tissir, Fadel. Guidance of motor axons: where do we stand?. In: Current Opinion in Physiology, Vol. 4, p. 76-81 (2018). doi:10.1016/j.cophys.2018.06.004.
2017
Kabayiza, Uwantege Karolina ; Masgutova, Gauhar ; Harris, Audrey ; Rucchin, Vincent ; Jacob, Benvenuto ; Clotman, Frédéric. The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development. In: Frontiers in Molecular Neuroscience, Vol. 10, no.n/A, p. n/A (2017). doi:10.3389/fnmol.2017.00157.
2016
Stanga, Serena ; Zanou, Bidossessi Nadège ; TASIAUX, Bernadette ; Contino, Sabrina ; Clotman, Frédéric ; Gailly, Philippe ; Dewachter, Ilse ; Octave, Jean-Noël ; Kienlen-Campard, Pascal. APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.. In: The FASEB Journal, Vol. 30, no. 5, p. 1696-711 (2016). doi:10.1096/fj.15-278739.
2016
Romanov, Roman A ; Zeisel, Amit ; Bakker, Joanne ; Girach, Fatima ; Hellysaz, Arash ; Tomer, Raju ; Alpár, Alán ; Mulder, Jan ; Clotman, Frédéric ; Keimpema, Erik ; Hsueh, Brian ; Crow, Ailey K ; Martens, Henrik ; Schwindling, Christian ; Calvigioni, Daniela ; Bains, Jaideep S ; Máté, Zoltán ; Szabó, Gábor ; Yanagawa, Yuchio ; Zhang, Ming-Dong ; Rendeiro, Andre ; Farlik, Matthias ; Uhlén, Mathias ; Wulff, Peer ; Bock, Christoph ; Broberger, Christian ; Deisseroth, Karl ; Hökfelt, Tomas ; Linnarsson, Sten ; Horvath, Tamas L ; Harkany, Tibor. Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.. In: Nature Neuroscience, Vol. 20, no. 2, p. 176-188 (Feb 2017). doi:10.1038/nn.4462.
2016
Francius, Cédric ; Hidalgo Figueroa, Maria ; Debrulle, Stéphanie ; Pelosi, Barbara ; Rucchin, Vincent ; Ronellenfitch, Kara ; Panayiotou, Elena ; Makrides, Neoklis ; Misra, Kamana ; Harris, Audrey ; Hassani, Hessameh ; Schakman, Olivier ; Parras, Carlos ; Xiang, Mengqing ; Malas, Stavros ; Chow, Robert L. ; Clotman, Frédéric. Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord. In: Frontiers in Molecular Neuroscience, Vol. 9, p. 145 [1-15] (2016). doi:10.3389/fnmol.2016.00145.
2015
Pirson, Marc ; Debrulle, Stéphanie ; Clippe, André ; Clotman, Frédéric ; Knoops, Bernard. Thioredoxin-2 modulates neuronal programmed cell death in the embryonic chick spinal cord in basal and target-deprived conditions.. In: PLoS One, Vol. 000, no.000, p. 1-21 (2015). doi:10.1371/journal.pone.0142280.
2014
Chai, Guoliang ; Zhou, Libing ; Manto, Mario ; Helmbacher, Françoise ; Clotman, Frédéric ; Goffinet, André ; Tissir, Fadel. Celsr3 is required in motor neurons to steer their axons in the hindlimb. In: Nature Neuroscience, Vol. 17, no. 9, p. 1171-1179 (2014). doi:10.1038/nn.3784.
2014
Francius, Cédric ; Clotman, Frédéric. Generating spinal motor neuron diversity: a long quest for neuronal identity. In: Cellular and Molecular Life Sciences, Vol. 71, no. 5, p. 813-829 (2014). doi:10.1007/s00018-013-1398-x.
2014
Francius, Cédric ; Ravassard, Philippe ; Hidalgo Figueroa, Maria ; Mallet, Jacques ; Clotman, Frédéric ; Nardelli, Jeannette. Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord.. In: Developmental Neurobiology, (2014). doi:10.1002/dneu.22244.
2014
des Rieux, Anne ; De Berdt, Pauline ; Ansorena Artieda, Eduardo ; Ucakar, Bernard ; Jacobs, Damien ; Schakman, Olivier ; Audouard, Emilie ; Bouzin, Caroline ; Auhl, Dietmar ; Simón-Yarza, Teresa ; Feron, Olivier ; Blanco-Prieto, Maria J ; Carmeliet, Peter ; Bailly, Christian ; Clotman, Frédéric ; Préat, Véronique. Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord. In: Journal of Biomedical Materials Research. Part A, Vol. 102, no. 7, p. 2345–2355 (2014). doi:10.1002/jbm.a.34915.
2013
Hermant, Pascale ; Francius, Cédric ; Clotman, Frédéric ; Michiels, Thomas. IFN-ε Is Constitutively Expressed by Cells of the Reproductive Tract and Is Inefficiently Secreted by Fibroblasts and Cell Lines.. In: PLoS One, Vol. 8, no.8, p. e71320 (2013). doi:10.1371/journal.pone.0071320.
2013
Francius, Cédric ; Harris, Audrey ; Rucchin, Vincent ; Hendricks, Timothy J ; Stam, Floor J ; Barber, Melissa ; Kurek, Dorota ; Grosveld, Frank G ; Pierani, Alessandra ; Goulding, Martyn ; Clotman, Frédéric. Identification of Multiple Subsets of Ventral Interneurons and Differential Distribution along the Rostrocaudal Axis of the Developing Spinal Cord.. In: PLoS One, Vol. 8, no.8, p. e70325 (2013). doi:10.1371/journal.pone.0070325.
2013
Panayiotou, Elena ; Panayi, Elena ; Lapathitis, George ; Francius, Cédric ; Clotman, Frédéric ; Kessaris, Nicoletta ; Richardson, William D ; Malas, Stavros. Pax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice.. In: Gene Expression Patterns, Vol. 13, no. 8, p. 328-334 (2013). doi:10.1016/j.gep.2013.06.004.
2013
Audouard, Emilie ; Schakman, Olivier ; Ginion, Audrey ; Bertrand, Luc ; Gailly, Philippe ; Clotman, Frédéric. The Onecut transcription factor HNF-6 contributes to proper reorganization of Purkinje cells during postnatal cerebellum development. In: Molecular and Cellular Neuroscience, Vol. 56, p. 159-68 (2013). doi:10.1016/j.mcn.2013.05.001.
2012
Chakrabarty, Koushik ; Von Oerthel, Lars ; Hellemons, Anita ; Clotman, Frédéric ; Espana-Bessy, Agnès ; Groot Koerkamp, Marian ; Holstege, Frank C P ; Pasterkamp, R Jeroen ; Smidt, Marten P. Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development.. In: Biology open, Vol. 1, no.8, p. 693-704 (2012). doi:10.1242/bio.20121230.
2012
Espana-Bessy, Agnès ; Clotman, Frédéric. Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.. In: Molecular and cellular neurosciences, Vol. 50, no.1, p. 93-102 (2012). doi:10.1016/j.mcn.2012.04.002.
2012
Roy, Agnès ; Francius, Cédric ; Rousso, David L ; Seuntjens, Eve ; Debruyn, Joke ; Luxenhofer, Georg ; Huber, Andrea B ; Huylebroeck, Danny ; Novitch, Bennett G ; Clotman, Frédéric. Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.. In: Development (Cambridge, England), Vol. 139, no.17, p. 3109-19 (2012). doi:10.1242/dev.078501.
2012
Audouard, Emilie ; Schakman, Olivier ; René, Frédérique ; Huettl, Rosa-Eva ; Huber, Andrea B. ; Loeffler, Jean-Philippe ; Gailly, Philippe ; Clotman, Frédéric. The Onecut Transcription Factor HNF-6 Regulates in Motor Neurons the Formation of the Neuromuscular Junctions. In: PLoS One, Vol. 7, no. 12, p. e50509 (2012). doi:10.1371/journal.pone.0050509.
2011
Espana-Bessy, Agnès ; Clotman, Frédéric. Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse. In: The Journal of Comparative Neurology, Vol. 520, no. 7, p. 1424 -1441 (2012). doi:10.1002/cne.22803.
2011
Stam, F.J. ; Hendricks, T.J. ; Zhang, J. ; Geiman, E.J. ; Francius, C. ; Labosky, P.A. ; Clotman, Frédéric ; Goulding, M.. Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. In: Development, Vol. 139, no. 1, p. 179-190 (2012). doi:10.1242/dev.071134.
2010
Francius, Cédric ; Clotman, Frédéric. Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.. In: Neuroscience, Vol. 165, no. 1, p. 116-29 (2010). doi:10.1016/j.neuroscience.2009.09.076.
Provided by DIAL