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FATH Publications
2022
Descamps, Olivier ; Demeure, Fabian ; Mertens, Ann ; Verhaegen, Ann ; Balligand, Jean-Luc ; Langlois, Michel ; Wallemacq, Caroline ; De Sutter, Johan ; Cals, Nathalie ; Rietzschel, Ernst. Acide bempédoïque : nouvelle option thérapeutique pour améliorer le profil lipidique des patients à risque cardiovasculaire élevé. In: Louvain médical, Vol. 141, no.3, p. 153-161 (2022).
2022
Spourquet, Catherine ; Delcorte, Ophélie ; Lemoine, Pascale ; Dauguet, Nicolas ; Loriot, Axelle ; Achouri, Younes ; Hollmén, Maija ; Jalkanen, Sirpa ; Huaux, François ; Lucas, Sophie ; Van Meerbeeck, Pierre ; Knauf, Jeffrey ; Fagin, James A. ; Dessy, Chantal ; Mourad, Michel ; Henriet, Patrick ; Tyteca, Donatienne ; Marbaix, Etienne ; Pierreux, Christophe. BRAFV600E expression in thyrocytes causes recruitment of immunosuppressive STABILIN-1 macrophages. In: Cancers (Basel), Vol. 14, no. 19, p. 4687 (2022). doi:10.3390/cancers14194687.
2022
Choteau, Mathilde ; Scohy, Anaïs ; Messe, Stéphane ; Luyckx, Mathieu ; Dechamps, Mélanie ; Montiel, Virginie ; Yombi, Jean Cyr ; Gruson, Damien ; Limaye, Nisha ; Michiels, Thomas ; Dumoutier, Laure. Development of SARS-CoV2 humoral response including neutralizing antibodies is not sufficient to protect patients against fatal infection.. In: Scientific reports, Vol. 12, no. 1, p. 2077 [1-12] (2022). doi:10.1038/s41598-022-06038-5.
2022
Tallarico, Roberta Teixeira ; Deniau, Benjamin ; Fong, Nicholas ; Ghosn, Jade ; Legrand, Matthieu. Differences in HADS and SF-36 scores 1 year after critical illness in COVID-19 patients., collab. French-COVID and the FROG-ICU Investigators ; Laterre, Pierre-François ; Montiel, Virginie ; Dujardin, Marie-France ; Berghe, Caroline. In: Intensive care medicine, Vol. 48, no.9, p. 1245-1247 (2022). doi:10.1007/s00134-022-06797-9.
2022
Trouvilliez, Sarah ; Cicero, Julien ; Lévêque, Romain ; Aubert, Léo ; Corbet, Cyril ; Van Outryve, Alexandre ; Streule, Karolin ; Angrand, Pierre-Olivier ; Völkel, Pamela ; Magnez, Romain ; Brysbaert, Guillaume ; Mysiorek, Caroline ; Gosselet, Fabien ; Bourette, Roland ; Adriaenssens, Eric ; Thuru, Xavier ; Lagadec, Chann ; de Ruyck, Jérôme ; Orian-Rousseau, Véronique ; Le Bourhis, Xuefen ; Toillon, Robert-Alain. Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells. In: Journal of Experimental & Clinical Cancer Research, Vol. 41, no.1, p. 110 (2022). doi:10.1186/s13046-022-02314-4.
2022
Lan, Junjie ; Cadassou, Octavia ; Corbet, Cyril ; Riant, Olivier ; Feron, Olivier. Discovery of Mitochondrial Complex I Inhibitors as Anticancer and Radiosensitizer Drugs Based on Compensatory Stimulation of Lactate Release. In: Cancers, Vol. 14, no.21, p. 5454 (2022). doi:10.3390/cancers14215454.
2022
Thabault, Léopold ; Brustenga, Chiara ; Savoyen, Perrine ; Van Gysel, Mégane ; Wouters, Johan ; Sonveaux, Pierre ; Frédérick, Raphaël ; Liberelle, Maxime. Discovery of small molecules interacting at lactate dehydrogenases tetrameric interface using a biophysical screening cascade.. In: European Journal of Medicinal Chemistry, Vol. 230, p. 114102 (2022). doi:10.1016/j.ejmech.2022.114102.
2022
d'Hose, Donatienne ; Mathieu, Barbara ; Mignion, Lionel ; Hardy, Micael ; Ouari, Olivier ; Jordan, Bénédicte ; Sonveaux, Pierre ; Gallez, Bernard. EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells.. In: Molecules (Basel, Switzerland), Vol. 27, no.18, p. 5872 (2022). doi:10.3390/molecules27185872.
2022
Sambon, Pauline ; Sellimi, Amina ; Kozyreff, Alexandra ; Gheysens, Olivier ; Pothen, Lucie ; Yildiz, Halil ; Van Pesch, Vincent. Epidemiology, clinical presentation, treatment, and outcome of neurosarcoidosis: A mono-centric retrospective study and literature review.. In: Frontiers in neurology, Vol. 13, p. 970168 (2022). doi:10.3389/fneur.2022.970168.
2022
Buyse, Chloe ; Joudiou, Nicolas ; Warscotte, Aude ; Richiardone, Elena ; Mignion, Lionel ; Corbet, Cyril ; Gallez, Bernard. Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification.. In: Metabolites, Vol. 12, no.6, p. 12pp (2022). doi:10.3390/metabo12060557.
2022
Kemps, Hannelore ; Dessy, Chantal ; Dumas, Laurent ; Sonveaux, Pierre ; Alders, Lotte ; Van Broekhoven, Jana ; Perez Font, Lena ; Lambrichts, Sara ; Foulquier, Sebastien ; Hendrix, Sven ; Brone, Bert ; Lemmens, Robin ; Bronckaers, Annelies. Extremely low frequency electromagnetic stimulation reduces ischemic stroke volume by improving central collateral blood flow. In: Journal of Cerebral Blood Flow and Metabolism, Vol. 42, no. 6, p. 979-996 (2022) (Accepté/Sous presse).
2022
Ward, Bradley ; Yombi, Jean Cyr ; Balligand, Jean-Luc ; Cani, Patrice D. ; Collet, Jean-François ; De Greef, Julien ; Dewulf, Joseph P. ; Gatto, Laurent ; Haufroid, Vincent ; Jodogne, Sébastien ; Kabamba-Mukadi, Benoît ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Elens, Laure ; Belkhir, Leïla. HYGIEIA: HYpothesizing the Genesis of Infectious Diseases and Epidemics through an Integrated Systems Biology Approach. In: Viruses, Vol. 14, no. 7, p. 1373 [1-17] (2022). doi:10.3390/v14071373.
2022
Brilot, Sarah ; Calvo Lasso De La Vega, Esther ; Michaux, Christian ; Belkhir, Leïla ; Pothen, Lucie. Hépatite fulminante compliquée d’un syndrome hémophagocytaire réactionnel chez un patient immunocompétent : deux manifestations rares d’une infection à Herpes simplex virus 1. In: Louvain médical, Vol. 141, no.9-10, p. 496-501 (2022).
2022
Dechamps, Mélanie ; De Poortere, Julien ; Martin, Manon ; Gatto, Laurent ; Daumerie, Aurélie ; Bouzin, Caroline ; Octave, Marie ; Ginion, Audrey ; Robaux, Valentine ; Pirotton, Laurence ; Bodart, Julie ; Gérard, Ludovic ; Montiel, Virginie ; Campion, Alessandro ; Gruson, Damien ; Van Dievoet, Marie-Astrid ; Douxfils, Jonathan ; Haguet, Hélène ; Morimont, Laure ; Derive, Marc ; Jolly, Lucie ; Bertrand, Luc ; Dumoutier, Laure ; Castanares Zapatero, Diego ; Laterre, Pierre-François ; Horman, Sandrine ; Beauloye, Christophe. Inflammation-Induced Coagulopathy Substantially Differs Between COVID-19 and Septic Shock: A Prospective Observational Study.. In: Frontiers in medicine, Vol. 8, p. 780750 [1-14] (2022). doi:10.3389/fmed.2021.780750.
2022
Van de Gucht, Melissa ; Dufait, Inès ; Kerkhove, Lisa ; Corbet, Cyril ; de Mey, Sven ; Jiang, Heng ; Law, Ka Lun ; Gevaert, Thierry ; Feron, Olivier ; De Ridder, Mark. Inhibition of Phosphoglycerate Dehydrogenase Radiosensitizes Human Colorectal Cancer Cells under Hypoxic Conditions. In: Cancers, Vol. 14, no.20, p. 5060 (2022). doi:10.3390/cancers14205060.
2022
Yildiz, Halil ; Pothen, Lucie (co-first author) ; Lefebvre, Chantal ; De Greef, Julien ; Belkhir, Leïla ; Vincent, Anne ; Roodhans, Fabien ; Balligand, Jean-Luc ; Yombi, Jean Cyr ; Hainaut, Philippe. Innovations 2021 en médecine interne et maladies infectieuses. In: Louvain médical, Vol. 141, no.2, p. 103-107 (2022).
2022
Weber DD ; Aminzadeh-Gohari S ; Thapa M ; Redtenbacher AS ; Catalano L ; De Miranda Capeloa, Tania Isabel ; Vazeille, Thibaut ; Emberger M ; Felder TK ; Feichtinger RG ; Koelblinger P ; Dallmann G ; Sonveaux, Pierre ; Lang R ; Kofler B. Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity. In: Cancer & Metabolism, Vol. 10, no. 1, p. 12 (2022).
2022
Ippolito, Luigi ; Sonveaux, Pierre ; Chiarugi, Paola. Lactate: unconventional roles of a nutrient along the tumor landscape. In: Trends in Endocrinology and Metabolism, Vol. 33, no. 4, p. 231-235 (2022).
2022
Richiardone, Elena ; Van den Bossche, Valentin ; Corbet, Cyril. Metabolic Studies in Organoids: Current Applications, Opportunities and Challenges. In: Organoids, Vol. 1, p. 85-105 (2022). doi:10.3390/ organoids1010008 (Accepté/Sous presse).
2022
Van den Bossche, Valentin ; Zaryouh, Hannah ; Vara-Messler, Marianela ; Vignau, Julie ; Machiels, Jean-Pascal ; Wouters, An ; Schmitz, Sandra ; Corbet, Cyril. Microenvironment-driven intratumoral heterogeneity in head and neck cancers: clinical challenges and opportunities for precision medicine.. In: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, Vol. 60, no.1, p. 100806 (2022). doi:10.1016/j.drup.2022.100806.
2022
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; d'Hose, Donatienne ; canas Rodriguez, Amanda ; Payen, Valery L ; Zampieri, Luca ; Van de Velde, Justine ; Benyahia, Zohra ; Pranzini, Erica ; Vazeille, Thibaut ; Fransolet, Maude ; Bouzin, Caroline ; Brusa, Davide ; Michiels, Carine ; Gallez, Bernard ; Murphy, Michael P ; Porporato, Paolo E ; Sonveaux, Pierre. MitoQ inhibits human breast cancer cell migration, invasion and clonogenicity. In: Cancers, Vol. 14, no. 6, p. 1516 (2022). doi:10.3390/cancers14061516.
2022
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; Canas Rodriguez, Amanda ; Payen, Valery L ; Zampieri, Luca ; Pranzini, Erica ; Derouane, Françoise ; Vazeille, Thibaut ; Bouzin, Caroline ; Duhoux, Francois ; Murphy, Michael P. ; Porporato, Paolo E ; Sonveaux, Pierre. MitoQ prevents human breast cancer recurrence and lung metastasis in mice. In: Cancers, Vol. 14, no.6, p. 1488 (2022). doi:10.3390/cancers14061488.
2022
Blackman, Marine ; De Miranda Capeloa, Tania Isabel ; Rondeau, Justin ; Zampieri, Luca ; Benyahia, Zohra ; Van de Velde, Justine ; Fransolet, Maude ; Daskalopoulos, Evangelos P. ; Michiels, Carine ; Beauloye, Christophe ; Sonveaux, Pierre. Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells. In: Cancers, Vol. 14, no.18, p. 4371 (2022). doi:10.3390/cancers14184371.
2022
Macchi, C ; Moregola, A ; Greco, MF ; Svecla, M ; Bonacina, F ; Dhup, Suveera ; Dadhich, Rakesh K ; Audano, M ; Sonveaux, Pierre ; Mauro, C ; Mitro, N ; Ruscica, M ; Norata, GD. Monocarboxylate transporter 1 deficiency impacts CD8 + T lymphocytes proliferation and recruitment to adipose tissue during obesity. In: iScience, Vol. 25, no. 6, p. 104435 (2022).
2022
Macchi, C ; Moregola, A ; Greco, M F ; Svecla, M ; Bonacina, F ; Dhup, S ; Dadhich, R K ; Audano, M ; Sonveaux, Pierre ; Mauro, C ; Mitro, N ; Ruscica, M ; Norata, G D. Monocarboxylate transporter 1 deficiency impacts CD8 T lymphocytes proliferation and recruitment to adipose tissue during obesity.. In: iScience, Vol. 25, no.6, p. 104435 (2022). doi:10.1016/j.isci.2022.104435.
2022
Montiel, Virginie ; Lobysheva, Irina ; Gérard, Ludovic ; Vermeersch, Marjorie ; Perez-Morga, David ; Castelein, Thomas ; Mesland, Jean-Baptiste ; Hantson, Philippe ; Collienne, Christine ; Gruson, Damien ; Van Dievoet, Marie-Astrid ; Persu, Alexandre ; Beauloye, Christophe ; Dechamps, Mélanie ; Belkhir, Leïla ; Robert, Annie ; Derive, Marc ; Laterre, Pierre-François ; Danser, A H J ; Wittebole, Xavier ; Balligand, Jean-Luc. Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients.. In: EBioMedicine, Vol. 77, p. 103893 [1-18] (2022). doi:10.1016/j.ebiom.2022.103893.
2022
Derouane, Françoise ; van Marcke, Cédric ; Berlière, Martine ; Gerday, Amandine ; Fellah, Latifa ; Leconte, Isabelle ; Van Bockstal, Mieke ; Galant, Christine ; Corbet, Cyril ; Duhoux, François. Predictive Biomarkers of Response to Neoadjuvant Chemotherapy in Breast Cancer: Current and Future Perspectives for Precision Medicine.. In: Cancers, Vol. 14, no.16, p. 3876 (2022). doi:10.3390/cancers14163876.
2022
d'Hose, Donatienne ; Mignion, Lionel ; Hamelin, Loïc ; Sonveaux, Pierre ; Jordan, Bénédicte ; Gallez, Bernard. Statins Alleviate Tumor Hypoxia in Prostate Cancer Models by Decreasing Oxygen Consumption: An Opportunity for Radiosensitization?. In: Biomolecules, Vol. 12, no.10, p. 1418 (2022). doi:10.3390/biom12101418.
2022
Pothen, Lucie ; Verdoy, Roxane ; De Mulder, Delphine ; Esfahani, Hrag ; Farah, Charlotte ; Michel, Lauriane ; Dei Zotti, Flavia ; Bearzatto, Bertrand ; Ambroise, Jérôme ; Bouzin, Caroline ; Dessy, Chantal ; Balligand, Jean-Luc. Sustained Downregulation of Vascular Smooth Muscle Acta2 After Transient Angiotensin II Infusion: A New Model of "Vascular Memory".. In: Frontiers in cardiovascular medicine, Vol. 9, p. 854361 [1-13] (2022). doi:10.3389/fcvm.2022.854361.
2022
Deskeuvre, Marine ; Lan, Junjie ; Dierge, Emeline ; Messens, Joris ; Riant, Olivier ; Corbet, Cyril ; Feron, Olivier ; Frédérick, Raphaël. Targeting cancer cells in acidosis with conjugates between the carnitine palmitoyltransferase 1 inhibitor etomoxir and pH (low) insertion peptides. In: International Journal of Pharmaceutics, Vol. 624, no.1, p. 122041 (2022). doi:10.1016/j.ijpharm.2022.122041.
2022
Cappellesso, Federica ; Orban, Marie-Pauline ; Shirgaonkar, Niranjan ; Berardi, Emanuele ; Serneels, Jens ; Neveu, Marie-Aline ; di Molfetta, Daria ; Piccapane, Francesca ; Caroppo, Rosa ; Debellis, Lucantonio ; Ostyn, Tessa ; Joudiou, Nicolas ; Mignion, Lionel ; Richiardone, Elena ; Jordan, Bénédicte ; Gallez, Bernard ; Corbet, Cyril ; Roskams, Tania ; Dasgupta, Ramanuj ; Tejpar, Sabine ; Di Matteo, Mario ; Taverna, Daniela ; Reshkin, Stephan Joel ; Topal, Baki ; Virga, Federico ; Mazzone, Massimiliano. Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer. In: Nature Cancer, Vol. 3, p. 1464-1483 (2022). doi:10.1038/s43018-022-00470-2.
2022
Yelek, Caner ; Mignion, Lionel ; Paquot, Adrien ; Bouzin, Caroline ; Corbet, Cyril ; Muccioli, Giulio ; Cani, Patrice D. ; Jordan, Bénédicte. Tumor Metabolism Is Affected by Obesity in Preclinical Models of Triple-Negative Breast Cancer. In: Cancers, Vol. 14, no. 3, p. 562 [1-16] (2022). doi:10.3390/cancers14030562.
2022
Delcorte, Ophélie ; Craps, Julie ; Mahibullah, Siam ; Spourquet, Catherine ; D'Auria, Ludovic ; Van Der Smissen, Patrick ; Dessy, Chantal ; Marbaix, Etienne ; Mourad, Michel ; Pierreux, Christophe. Two miRNAs enriched in plasma extracellular vesicles are potential biomarkers for thyroid cancer.. In: Endocrine - Related Cancer, Vol. 29, no.7, p. 389-401 (2022). doi:10.1530/ERC-21-0343.
2022
Craps, Julie ; Joris, Virginie ; Baldeschi, Lelio ; Daumerie, Chantal ; Camboni, Alessandra ; Buemi, Antoine ; Lengelé, Benoît ; Behets Wydemans, Catherine ; Boschi, Antonella ; Mourad, Michel ; Many, Marie-Christine ; Dessy, Chantal. miR-199a Downregulation as a Driver of the NOX4/HIF-1α/VEGF-A Pathway in Thyroid and Orbital Adipose Tissues from Graves' Patients.. In: International Journal of Molecular Sciences, Vol. 23, no.1, p. 153 (2021). doi:10.3390/ijms23010153.
2021
Ngo Njembe, Monique T. ; Pachikian, Barbara ; Lobysheva, Irina ; Van Overstraeten, Nancy ; Dejonghe, Louis ; Verstraelen, Eleonore ; Buchet, Marine ; Rasse, Catherine ; Gardin, Cécile ; Mignolet, Eric ; Balligand, Jean-Luc ; Larondelle, Yvan. A Three-Month Consumption of Eggs Enriched With ω-3, ω-5 and ω-7 Polyunsaturated Fatty Acids Significantly Decreases the Waist Circumference of Subjects at Risk of Developing Metabolic Syndrome: A Double-Blind Randomized Controlled Trial. In: Nutrients, Vol. 13, no. 2, p. 663 [1-17] (2021). doi:10.3390/nu13020663.
2021
Soret, Perrine ; Le Dantec, Christelle ; Desvaux, Emiko ; Foulquier, Nathan ; Chassagnol, Bastien ; Hubert, Sandra ; Jamin, Christophe ; Barturen, Guillermo ; Desachy, Guillaume ; Devauchelle-Pensec, Valérie ; Boudjeniba, Cheïma ; Cornec, Divi ; Saraux, Alain ; Jousse-Joulin, Sandrine ; Barbarroja, Nuria ; Rodríguez-Pintó, Ignasi ; De Langhe, Ellen ; Beretta, Lorenzo ; Chizzolini, Carlo ; Kovács, László ; Witte, Torsten ; Bettacchioli, Eléonore ; Buttgereit, Anne ; Makowska, Zuzanna ; Lesche, Ralf ; Borghi, Maria Orietta ; Martin, Javier ; Courtade-Gaiani, Sophie ; Xuereb, Laura ; Guedj, Mickaël ; Moingeon, Philippe ; Alarcón-Riquelme, Marta E ; Laigle, Laurence ; Pers, Jacques-Olivier. A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome., collab. PRECISESADS Clinical Consortium ; PRECISESADS Flow Cytometry Consortium ; Lauwerys, Bernard ; Ducreux, Julie ; Maudoux, Anne-Lise. In: Nature communications, Vol. 12, no.1, p. 3523 [1-18] (2021). doi:10.1038/s41467-021-23472-7.
2021
Dufeys, Cécile ; Daskalopoulos, Evangelos-Panagiotis (co-first author) ; Castanares Zapatero, Diego ; Conway, Simon J. ; Ginion, Audrey ; Bouzin, Caroline ; Ambroise, Jérôme ; Bearzatto, Bertrand ; Gala, Jean-Luc ; Heymans, Stephane ; Papageorgiou, Anna-Pia ; Vinckier, Stefan ; Cumps, Julien ; Balligand, Jean-Luc ; Vanhaverbeke, Maarten ; Sinnaeve, Peter ; Janssens, Stefan ; Bertrand, Luc ; Beauloye, Christophe ; Horman, Sandrine. AMPKα1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism. In: Basic Research in Cardiology, Vol. 116, p. 10 [1-20] (2021). doi:10.1007/s00395-021-00846-y.
2021
Morelle, Johann ; Marechal, Céline ; Yu, Zanzhe ; Debaix, Huguette ; Corre, Tanguy ; Lambie, Mark ; Verduijn, Marion ; Dekker, Friedo ; Bovy, Philippe ; Evenepoel, Pieter ; Bammens, Bert ; Selgas, Rafael ; Bajo, Maria A. ; Coester, Annemieke M. ; Sow-Diallo, Amadou ; Hautem, Nicolas ; Struijk, Dirk G. ; Krediet, Raymond T. ; Balligand, Jean-Luc ; Goffin, Eric ; Crott, Ralph ; Ripoche, Pierre ; Davies, Simon ; Devuyst, Olivier. AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. In: New England Journal of Medicine, Vol. 385, no. 17, p. 1570-1580 (2021). doi:10.1056/nejmoa2034279.
2021
Colson, Arthur ; Sonveaux, Pierre ; Debiève, Frédéric ; Sferruzzi-Perri, Amanda N. Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction. In: Human Reproduction Update, Vol. 27, no. 3, p. 531-569 (2021). doi:10.1093/humupd/dmaa053.
2021
Balligand, Jean-Luc ; Michel, Lauriane. Assembling fats and sugar for cardiac protection. In: European heart journal, Vol. 42, no. 13, p. 4493–4495 (2021). doi:10.1093/eurheartj/ehab606.
2021
Boulanger, Cécile ; Chatzis, Olga ; Nolf, Delphine ; Brichard, Bénédicte ; Lauwerys, Bernard ; Nassogne, Marie-Cécile ; Limaye, Nisha. Atypical phenotype? The answer’s in the genotype: AGS caused by a novel RNASEH2C variant combined with XLA caused by a BTK deficiency.. In: Rheumatology, Vol. 60, no. 7, p. e240-e242 (2021). doi:10.1093/rheumatology/keab051.
2021
Michel, Lauriane ; Balligand, Jean-Luc. Bèta-3-adrenerge receptoragonisten : therapeutisch potentieel bij de behandeling van prediabetes en hartfalen. In: Bloedvaten Hart Longen, Vol. 26, no.4, p. 27-32 (2021).
2021
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Danhaive, Olivier ; Hubinont, Corinne ; Sonveaux, Pierre ; Debieve, Frédéric. COVID-19 during Pregnancy: Clinical and In Vitro Evidence against Placenta Infection at Term by SARS-CoV-2.. In: The American journal of pathology, Vol. 191, no. 9, p. 1610-1623 (2021). doi:10.1016/j.ajpath.2021.05.009.
2021
Maury, Eléonore ; Navez, Benoît ; Brichard, Sonia. Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation.. In: Nature communications, Vol. 12, no. 1, p. 2388 [1-17] (2021). doi:10.1038/s41467-021-22571-9.
2021
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Danhaive, Olivier ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2.. In: The American journal of pathology, Vol. 191, no. 9, p. 1610-1623 (2021). doi:10.1016/j.ajpath.2021.05.009.
2021
Lysy, Philippe ; Absil, Hélène ; Gasser, Emy ; Boughaleb, Hasnae ; Barrea, Thierry ; Moniotte, Stéphane. Combined Algorithm-Based Adaptations of Insulin Dose and Carbohydrate Intake During Exercise in Children With Type 1 Diabetes: Results From the CAR2DIAB Study. In: Frontiers in endocrinology, Vol. 12, p. 658311 [1-8] (2021). doi:10.3389/fendo.2021.658311.
2021
Triaille, Clément ; Durez, Patrick ; Sokolova, Tatiana ; Tilman, Gaëlle ; Méric de Bellefon, Laurent ; Galant, Christine ; Coulie, Pierre G. ; Lauwerys, Bernard ; Limaye, Nisha. Common Transcriptomic Effects of Abatacept and Other DMARDs on Rheumatoid Arthritis Synovial Tissue. In: Frontiers in immunology, Vol. 12, p. 724895 [1-9] (2021). doi:10.3389/fimmu.2021.724895.
2021
De Greef, Julien ; Scohy, Anaïs ; Zech, Francis ; Aboubakar Nana, Frank ; Pilette, Charles ; Gérard, Ludovic ; Pothen, Lucie ; Yildiz, Halil ; Belkhir, Leïla ; Yombi, Jean Cyr. Determinants of IgG antibodies kinetics after severe and critical COVID-19.. In: Journal of medical virology, Vol. 93, no. 9, p. 5416-5424 (2021). doi:10.1002/jmv.27059.
2021
Van Den Brûle, Sybille ; Rappe, Margaux ; Ambroise, Jérôme ; Bouzin, Caroline ; Dessy, Chantal ; Paquot, Adrien ; Muccioli, Giulio ; Lison, Dominique. Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice.. In: Particle and fibre toxicology, Vol. 18, no. 1, p. 7 [1-15] (2021). doi:10.1186/s12989-021-00400-7.
2021
Thabault, Léopold ; Liberelle, Maxime ; Koruza, Katarina ; Yildiz, Esra ; Joudiou, Nicolas ; Messens, Joris ; Brisson, Lucie ; Wouters, Johan ; Sonveaux, Pierre ; Frédérick, Raphaël. Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides. In: Journal of Biological Chemistry, Vol. 296, p. 100422 (2021). doi:10.1016/j.jbc.2021.100422.
2021
Van Regemorter, Elliott ; Joris, Virginie ; Van Regemorter, Victoria ; Marique, Lancelot ; Behets Wydemans, Catherine ; Lengelé, Benoît ; Boschi, Antonella ; Baldeschi, Lelio ; Daumerie, Chantal ; Many, Marie-Christine ; Craps, Julie. Downregulation of Caveolin-1 and Upregulation of Deiodinase 3, Associated with Hypoxia-Inducible Factor-1α Increase, Are Involved in the Oxidative Stress of Graves' Orbital Adipocytes. In: Thyroid, Vol. 31, no. 4, p. 627-637 (2021). doi:10.1089/thy.2020.0238.
2021
Vincenti, Marie ; Farah, Charlotte ; Amedro, Pascal ; Scheuermann, Valerie ; Lacampagne, Alain ; Cazorla, Olivier. Early Myocardial Dysfunction and Benefits of Cardiac Treatment in Young X-Linked Duchenne Muscular Dystrophy Mice.. In: Cardiovascular drugs and therapy, , p. [1-11] (2021). doi:10.1007/s10557-021-07218-7.
2021
Valenti, Maria Teresa ; Mottes, Monica ; Dalle Carbonare, Luca ; Feron, Olivier. Editorial: Bone Metastases.. In: Frontiers in oncology, Vol. 11, p. 741515 (2021). doi:10.3389/fonc.2021.741515.
2021
Martin Corrons, Inès ; Braem, Fred ; Baudet, Lia ; Poncin, William ; Fizaine, Stéphane ; Aboubakar Nana, Frank ; Froidure, Antoine ; Pilette, Charles ; Liistro, Giuseppe ; De Greef, Julien ; Yildiz, Halil ; Pothen, Lucie ; Yombi, Jean Cyr ; Belkhir, Leïla ; Reychler, Gregory. Follow-up of functional exercise capacity in patients with COVID-19: It is improved by telerehabilitation.. In: Respiratory medicine, Vol. 183, p. 106438 [1-5] (2021). doi:10.1016/j.rmed.2021.106438.
2021
Guilmot, Antoine ; Maldonado Slootjes, Sofia Ijke ; Sellimi, Amina ; Bronchain, Maroussia ; Hanseeuw, Bernard ; Belkhir, Leïla ; Yombi, Jean Cyr ; De Greef, Julien ; Pothen, Lucie ; Yildiz, Halil ; Duprez, Thierry ; Fillee, Catherine ; Anantharajah, Ahalieyah ; Capes, Antoine ; Hantson, Philippe ; Jacquerye, Philippe ; Raymackers, Jean-Marc ; London, Frédéric ; El Sankari, Souraya ; Ivanoiu, Adrian ; Maggi, Pietro ; Van Pesch, Vincent. Immune-mediated neurological syndromes in SARS-CoV-2-infected patients.. In: Journal of neurology, Vol. 268, no. 3, p. 751-757 (2021). doi:10.1007/s00415-020-10108-x.
2021
Buyse, Chloé ; Joudiou, Nicolas ; Corbet, Cyril ; Feron, Olivier ; Mignion, Lionel ; Flament, Julien ; Gallez, Bernard. Impact of Inhibition of the Mitochondrial Pyruvate Carrier on the Tumor Extracellular pH as Measured by CEST-MRI. In: Cancers, Vol. 13, no.17, p. 4278 (2021). doi:10.3390/cancers13174278.
2021
Poncin, William ; Baudet, Lia ; Reychler, Gregory ; Duprez, Frédéric ; Liistro, Giuseppe ; Belkhir, Leïla ; Pothen, Lucie ; Yildiz, Halil ; Yombi, Jean Cyr ; De Greef, Julien. Impact of an improvised system on preserving oxygen supplies in patients with COVID- 19.. In: Archivos de Bronconeumologia, Vol. 57, p. 77-79 (2021). doi:10.1016/j.arbres.2020.07.019.
2021
Gonçalves, Ana Cristina ; Richiardone, Elena ; Jorge, Joana ; Polónia, Bárbara ; Xavier, Cristina P.R. ; Salaroglio, Iris Chiara ; Riganti, Chiara ; Vasconcelos, M. Helena ; Corbet, Cyril ; Sarmento-Ribeiro, Ana Bela. Impact of cancer metabolism on therapy resistance – Clinical implications. In: Drug Resistance Updates, , p. 100797 (2021). doi:10.1016/j.drup.2021.100797 (Accepté/Sous presse).
2021
Lasswitz, Lisa ; Gunesch, Antonia P. ; Kasten, Martina ; Zapatero-Belinchon, Francisco J. ; Brogden, Graham ; Gerold, Gisa ; Pietschmann, Thomas ; Montiel, Virginie ; Balligand, Jean-Luc ; Facciotti, Federica ; Hirsch, Emilio ; Gausepohl, Thomas ; Elbahesh, Husni ; Rimmelzwaan, Guus F. ; Höfer, Anne ; Kühnel, Mark P. ; Jonigk, Danny ; Eigendorf, Julian ; Tegtbur, Uwe ; Mink, Lena ; Scherr, Michaela ; Illig, Thomas ; Schambach, Axel ; Pfeffer, Tobias J. ; Hilfiker, Andres ; Haverich, Axel ; Hilfiker-Kleiner, Denise. Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease, collab. Ricke-Hoch, Melanie ; Stelling, Elisabeth. In: PLoS One, Vol. 16, no. 8, p. e0255335 [1-24] (2021). doi:10.1371/journal.pone.0255335.
2021
Benyahia, Zohra ; Blackman, Marine ; Hamelin, Loïc ; Zampieri, Luca ; De Miranda Capeloa, Tania Isabel ; Bedin, Marie ; Vazeille, Thibaut ; Schakman, Olivier ; Sonveaux, Pierre. In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment. In: Cancers, Vol. 13, no.3, p. 569 (2021). doi:10.3390/cancers13030569.
2021
Gérard, Ludovic ; Lecocq, Marylène ; Bouzin, Caroline ; Hoton, Delphine ; Schmit, Gregory ; Pinto Pereira, Joao ; Montiel, Virginie ; Plante-Bordeneuve, Thomas ; Laterre, Pierre-François ; Pilette, Charles. Increased Angiotensin-Converting Enzyme 2 and Loss of Alveolar Type II Cells in COVID-19-related Acute Respiratory Distress Syndrome.. In: American journal of respiratory and critical care medicine, Vol. 204, no.9, p. 1024-1034 (2021). doi:10.1164/rccm.202012-4461OC.
2021
Froidure, Antoine ; Mahsouli, Amin ; Liistro, Giuseppe ; De Greef, Julien ; Belkhir, Leïla ; Gerard, Ludovic ; Bertrand, Aurélie ; Koenig, Sandra ; Pothen, Lucie ; Yildiz, Halil ; Mwenge, Gimbada Benny ; Aboubakar Nana, Frank ; Gohy, Sophie ; Pilette, Charles ; Reychler, Gregory ; Coche, Emmanuel ; Yombi, Jean Cyr ; Ghaye, Benoît. Integrative respiratory follow-up of severe COVID-19 reveals common functional and lung imaging sequelae.. In: Respiratory medicine, Vol. 181, p. 106383 [1-6] (2021). doi:10.1016/j.rmed.2021.106383.
2021
Michel, Lauriane ; Balligand, Jean-Luc. Les agonistes des récepteurs adrénergiques Beta-3 : potentiel thérapeutique dans le traitement du prédiabète et de l'insuffisance cardiaque. In: Vaisseaux cœur poumons, Vol. 26, no.4, p. 27-32 (2021).
2021
Virga, Federico ; Cappellesso, Federica ; Stijlemans, Benoit ; Henze, Anne-Theres ; Trotta, Rosa ; Van Audenaerde, Jonas ; Mirchandani, Ananda S. ; Sanchez-Garcia, Manuel A. ; Vandewalle, Jolien ; Orso, Francesca ; Riera-Domingo, Carla ; Griffa, Alberto ; Ivan, Cristina ; Smits, Evelien ; Laoui, Damya ; Martelli, Fabio ; Langouche, Lies ; Van den Berghe, Greet ; Feron, Olivier ; Ghesquière, Bart ; Prenen, Hans ; Libert, Claude ; Walmsley, Sarah R. ; Corbet, Cyril ; Van Ginderachter, Jo A. ; Ivan, Mircea ; Taverna, Daniela ; Mazzone, Massimiliano. Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation. In: Science Advances, Vol. 7, no.19, p. eabf0466 (2021). doi:10.1126/sciadv.abf0466.
2021
Zampieri, Luca ; Da Silva Almeida, Ana Catarina ; Rondeau, Justin ; Sonveaux, Pierre. Mitochondrial Transfer in Cancer: A Comprehensive Review. In: International Journal of Molecular Sciences, Vol. 22, no.6, p. 3245 (2021). doi:10.3390/ijms22063245.
2021
Zampieri, Luca ; Sboarina, Martina ; Cacace, Andrea ; Grasso, Debora ; Thabault, Léopold ; Hamelin, Loïc ; Vazeille, Thibaut ; Dumon, Elodie ; Rossignol, Rodrigue ; Frédérick, Raphaël ; Sonveaux, Etienne ; Lefranc, Florence ; Sonveaux, Pierre. Olaparib is a mitochondrial Complex I inhibitor that kills temozolomide-resistant human glioblastoma cells. In: International Journal of Molecular Sciences, Vol. 22, no.11938, p. 17 (2021). doi:10.3390/ijms222111938.
2021
Hepp, Michael ; Wérion, Alexis ; De Greef, Axel ; de Ville de Goyet, Christine ; de Bournonville, Marc ; Behets Wydemans, Catherine ; Lengelé, Benoît ; Daumerie, Chantal ; Mourad, Michel ; Ludgate, Marian ; Many, Marie-Christine ; Joris, Virginie ; Craps, Julie. Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto's Thyroiditis.. In: International Journal of Molecular Sciences (Print), Vol. 22, no. 8, p. 3806 (2021). doi:10.3390/ijms22083806.
2021
Hepp, Michael ; Craps, Julie. Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto's Thyroiditis., collab. Wérion, Alexis ; De Greef, Axel ; de Ville de Goyet, Christine ; de Bournonville, Marc ; Behets Wydemans, Catherine ; Lengele, Benoit ; Daumerie, Chantal ; Mourad, Michel ; Ludgate, Marian ; Many, Marie-Christine ; Joris, Virginie. In: International journal of molecular sciences, Vol. 22, no.8 (2021). doi:10.3390/ijms22083806.
2021
Dierge, Emeline ; Debock, Elena ; Guilbaud, Céline ; Corbet, Cyril ; Mignolet, Eric ; Mignard, Louise ; Bastien, Estelle ; Dessy, Chantal ; Larondelle, Yvan ; Feron, Olivier. Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects. In: Cell Metabolism, Vol. S1550-4131, no.21, p. 00233-3 (2021). doi:10.1016/j.cmet.2021.05.016.
2021
Ughetto, Stefano ; Migliore, Cristina ; Pietrantonio, Filippo ; Apicella, Maria ; Petrelli, Annalisa ; D'Errico, Laura ; Durando, Stefania ; Moya-Rull, Daniel ; Bellomo, Sara E ; Rizzolio, Sabrina ; De Miranda Capeloa, Tania Isabel ; Ribisi, Salvatore ; Degiuli, Maurizio ; Reddavid, Rossella ; Rapa, Ida ; Fumagalli, Uberto ; De Pascale, Stefano ; Ribero, Dario ; Baronchelli, Carla ; Sgroi, Giovanni ; Rausa, Emanuele ; Baiocchi, Gian Luca ; Molfino, Sarah ; Manenti, Stefania ; Bencivenga, Maria ; Sacco, Michele ; Castelli, Claudia ; Siena, Salvatore ; Sartore-Bianchi, Andrea ; Tosi, Federica ; Morano, Federica ; Raimondi, Alessandra ; Prisciandaro, Michele ; Gloghini, Annunziata ; Marsoni, Silvia ; Sottile, Antonino ; Sarotto, Ivana ; Sapino, Anna ; Marchiò, Caterina ; Cassoni, Paola ; Guarrera, Simonetta ; Corso, Simona ; Giordano, Silvia. Personalized therapeutic strategies in HER2-driven gastric cancer.. In: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, Vol. 24, no.4, p. 897-912 (2021). doi:10.1007/s10120-021-01165-w.
2021
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Azevedo, Ricardo Bentes ; Feron, Olivier ; Amorim, Christiani A. Photodynamic cancer therapy using liposomes as an advanced vesicular photosensitizer delivery system.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 339, p. 75-90 (2021). doi:10.1016/j.jconrel.2021.09.024 (Accepté/Sous presse).
2021
Yildiz, Halil ; Castanares Zapatero, Diego ; Hannesse, Colin ; Vandermeersch, Denis ; Pothen, Lucie ; Yombi, Jean Cyr. Prospective validation and comparison of COVID-GRAM, NEWS2, 4C mortality score, CURB-65 for the prediction of critical illness in COVID-19 patients.. In: Infectious diseases, Vol. 53, no.8, p. 640-642 (2021). doi:10.1080/23744235.2021.1896777.
2021
Vermonden, Perrine ; Vancoppenolle, Matthias ; Dierge, Emeline ; Mignolet, Eric ; Cuvelier, Géraldine ; Knoops, Bernard ; Page, Melissa ; Debier, Cathy ; Feron, Olivier ; Larondelle, Yvan. Punicic Acid Triggers Ferroptotic Cell Death in Carcinoma Cells. In: Nutrients, Vol. 13, no. 8, p. 2751 [1-16] (2021). doi:10.3390/nu13082751.
2021
van Marcke, Cédric ; Honoré, Natasha (co-first author) ; van der Elst, Athénaïs (co-first author) ; Beyaert, Simon ; Derouane, Françoise ; Dumont, Caroline ; Aboubakar Nana, Frank ; Baurain, Jean-François ; Borbath, Ivan ; Collard, Philippe ; Cornelis, Frank ; De Cuyper, Astrid ; Duhoux, Francois ; Filleul, Bertrand ; Galot, Rachel ; Gizzi, Marco ; Mazzeo, Filomena ; Pieters, Thierry ; Seront, Emmanuel ; Sinapi, Isabelle ; Van Den Eynde, Marc ; Whenham, Nicolas ; Yombi, Jean Cyr ; Scohy, Anaïs ; van Maanen, Aline ; Machiels, Jean-Pascal. Safety of systemic anti-cancer treatment in oncology patients with non-severe COVID-19: a cohort study.. In: BMC cancer, Vol. 21, no.1, p. 578 [1-12] (2021). doi:10.1186/s12885-021-08349-8.
2021
Vander Linden, Catherine ; Corbet, Cyril ; Bastien, Estelle ; Martherus, Ruben ; Guilbaud, Céline ; Petit, Laurenne ; Wauthier, Loris ; Loriot, Axelle ; De Smet, Charles ; Feron, Olivier. Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition. In: Cell Reports, Vol. 35, no.9, p. 109202 (2021). doi:10.1016/j.celrep.2021.109202.
2021
Yildiz, Halil ; Castanares Zapatero, Diego ; Pierman, Guillaume ; Pothen, Lucie ; De Greef, Julien ; Aboubakar Nana, Frank ; Rodriguez-Villalobos, Hector ; Belkhir, Leïla ; Yombi, Jean Cyr. Validation of Neutrophil-to-Lymphocyte Ratio Cut-off Value Associated with High In-Hospital Mortality in COVID-19 Patients.. In: International journal of general medicine, Vol. 14, p. 5111-5117 (2021). doi:10.2147/IJGM.S326666.
2021
Balligand, Jean-Luc ; Bertrand, Luc. You “heart” what you eat!. In: Cardiovascular Research, Vol. 03, no.10, p. 00 (2021). doi:10.1093/cvr/cvab118.
2020
Maron, Bradley A ; Altucci, Lucia ; Balligand, Jean-Luc ; Baumbach, Jan ; Ferdinandy, Peter ; Filetti, Sebastiano ; Parini, Paolo ; Petrillo, Enrico ; Silverman, Edwin K ; Barabási, Albert-László ; Loscalzo, Joseph. A global network for network medicine., collab. International Network Medicine Consortium. In: NPJ systems biology and applications, Vol. 6, no.1, p. 29 [1-3] (2020). doi:10.1038/s41540-020-00143-9.
2020
Nkuipou-Kenfack, Esther ; Latosinska, Agnieszka ; Yang, Wen-Yi ; Fournier, Marie-Céline ; Blet, Alice ; Mujaj, Blerim ; Thijs, Lutgarde ; Feliot, Elodie ; Gayat, Etienne ; Mischak, Harald ; Staessen, Jan A ; Mebazaa, Alexandre ; Zhang, Zhen-Yu. A novel urinary biomarker predicts 1-year mortality after discharge from intensive care., collab. French and European Outcome Registry in Intensive Care Unit Investigators ; Laterre, Pierre-François ; Montiel, Virginie ; Dujardin, Marie-France ; Berghe, Caroline. In: Critical care (London, England), Vol. 24, no.1, p. 10 [1-11] (2020). doi:10.1186/s13054-019-2686-0.
2020
Yelek, Caner ; Mignion, Lionel ; Joudiou, Nicolas ; Terrasi, Romano ; Gourgue, Florian ; Van Hul, Matthias ; Delzenne, Nathalie M. ; Gallez, Bernard ; Corbet, Cyril ; Muccioli, Giulio ; Feron, Olivier ; Cani, Patrice D. ; Jordan, Bénédicte. Acetate: Friend or foe against breast tumour growth in the context of obesity?. In: Journal of Cellular and Molecular Medicine, Vol. 24, no. 24, p. 14195-14204 (2020). doi:10.1111/jcmm.16034.
2020
Trempolec, Natalia ; Degavre, Charline ; Doix, Bastien ; Brusa, Davide ; Corbet, Cyril ; Feron, Olivier. Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response. In: Cancers, Vol. 12, no. 5, p. 1284 [1-17] (2020). doi:10.3390/cancers12051284.
2020
Schoonjans, Céline ; Joudiou, Nicolas ; Brusa, Davide ; Corbet, Cyril ; Feron, Olivier ; Gallez, Bernard. Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate. In: Cancer Letters, Vol. 470, p. 18-28 (2020). doi:10.1016/j.canlet.2019.12.003.
2020
Scheinok, Samantha ; De Miranda Capeloa, Tania Isabel ; Porporato, Paolo E ; Sonveaux, Pierre ; Gallez, Bernard. An EPR study using cyclic hydroxylamines to assess the level of mitochondrial ROS in superinvasive cancer cells. In: Cell biochemistry and biophysics, Vol. 78, no. 3, p. 249-254 (2020). doi:10.1007/s12013-020-00921-6.
2020
Dubois-Deruy, Emilie ; Gelinas, Roselle ; Beauloye, Christophe ; Esfahani, Hrag ; Michel, Lauriane ; Dessy, Chantal ; Bertrand, Luc ; Balligand, Jean-Luc. Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP-activated protein kinase and autophagy.. In: ESC heart failure, Vol. 7, no. 3, p. 920-932 (2020). doi:10.1002/ehf2.12648.
2020
Darius, Tom ; Vergauwen, Martial ; Smith, Thomas ; Gerin, Isabelle ; Joris, Virginie ; Mueller, Matteo ; Aydin, Selda ; Muller, Xavier ; Schlegel, Andrea ; Nath, Jay ; Ludwig, Christian ; Dessy, Chantal ; Many, Marie-Christine ; Bommer, Guido ; Dutkowski, Philipp ; Gianello, Pierre ; Mourad, Michel. Brief O uploading during continuous hypothermic machine perfusion is simple yet effective oxygenation method to improve initial kidney function in a porcine autotransplant model.. In: American journal of transplantation, Vol. 20, no. 8, p. 2030-2043 (2020). doi:10.1111/ajt.15800.
2020
Darius, Tom ; Vergauwen, Martial ; Smith, Thomas ; Gerin, Isabelle ; Joris, Virginie ; Mueller, Matteo ; Aydin, Selda ; Muller, Xavier ; Schlegel, Andrea ; Nath, Jay ; Ludwig, Christian ; Dessy, Chantal ; Many, Marie-Christine ; Bommer, Guido ; Dutkowski, Philipp ; Gianello, Pierre ; Mourad, Michel. Brief oxygen uploading during continuous hypothermic machine perfusion is simple yet effective oxygenation method to improve initial kidney function in a porcine autotransplant model.. In: American journal of transplantation, Vol. 20, no. 8, p. 2030-2043 (2020). doi:10.1111/ajt.15800.
2020
De Greef, Julien ; Pothen, Lucie ; Yildiz, Halil ; Poncin, William ; Reychler, Gregory ; Brilot, Sarah ; Demartin, Sophie ; Lagneaux, Eugénie ; Lattenist, Raphaël ; Lux, Jeanne ; Pierman, Guillaume ; Vandercam, Geoffroy ; Wallemacq, Silvio ; Scohy, Anaïs ; Verroken, Alexia ; Mwenge, Benny ; Liistro, Giuseppe ; Froidure, Antoine ; Pilette, Charles ; Belkhir, Leïla ; Yombi, Jean Cyr. COVID-19 : infection par le virus SARS-CoV-2. In: Louvain médical, Vol. 139, no.5-6, p. 290-301 (2020).
2020
Dierge, Emeline ; Larondelle, Yvan ; Feron, Olivier. Cancer diets for cancer patients: Lessons from mouse studies and new insights from the study of fatty acid metabolism in tumors. In: Biochimie, Vol. 178, p. 56-68 (2020). doi:10.1016/j.biochi.2020.08.020.
2020
Carlier, François ; Dupasquier, Sébastien ; Ambroise, Jérôme ; Detry, Bruno ; Lecocq, Marylène ; Biétry–Claudet, Charline ; Boukala, Yassine ; Gala, Jean-Luc ; Bouzin, Caroline ; Verleden, Stijn E. ; Hoton, Delphine ; Gohy, Sophie ; Bearzatto, Bertrand ; Pilette, Charles. Canonical WNT pathway is activated in the airway epithelium in chronic obstructive pulmonary disease. In: EBioMedicine, Vol. 61, p. 103034 [1-17] (2020). doi:10.1016/j.ebiom.2020.103034.
2020
Delprat, Victor ; Tellier, Céline ; Demazy, Catherine ; Raes, Martine ; Feron, Olivier ; Michiels, Carine. Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway. In: Scientific Report, Vol. 10, no. 1, p. 882 (2020).
2020
Raj, Prithvi ; Song, Ran ; Zhu, Honglin ; Riediger, Linley ; Jun, Dong-Jae ; Liang, Chaoying ; Arana, Carlos ; Zhang, Bo ; Gao, Yajing ; Wakeland, Benjamin E ; Dozmorov, Igor ; Zhou, Jinchun ; Kelly, Jennifer A ; Lauwerys, Bernard ; Guthridge, Joel M ; Olsen, Nancy J ; Nath, Swapan K ; Pasare, Chandrashekhar ; van Oers, Nicolai ; Gilkeson, Gary ; Tsao, Betty P ; Gaffney, Patrick M ; Gregersen, Peter K ; James, Judith A ; Zuo, Xiaoxia ; Karp, David R ; Li, Quan-Zhen ; Wakeland, Edward K. Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.. In: Genome biology, Vol. 21, no.1, p. 281 [1-26] (2020). doi:10.1186/s13059-020-02184-z.
2020
de Mey, Sven ; Dufait, Inès ; Jiang, Heng ; Corbet, Cyril ; Wang, Hui ; Van De Gucht, Melissa ; Kerkhove, Lisa ; Law, Ka Lun ; Vandenplas, Hugo ; Gevaert, Thierry ; Feron, Olivier ; De Ridder, Mark. Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells. In: International Journal of Molecular Sciences, Vol. 21, no.24, p. 9367 (2020). doi:10.3390/ijms21249367.
2020
Corbet, Cyril ; Prieur, Alexandre. Editorial: Therapeutic Targeting of Cancer Stem-Like Cells (CSC) – The Current State of the Art. In: Frontiers in Oncology, Vol. 10, no.243, p. 1 (2020). doi:10.3389/fonc.2020.00243.
2020
Scarcello, Eleonora ; Lobysheva, Irina ; Bouzin, Caroline ; Jacques, Pascal ; Lison, Dominique ; Dessy, Chantal. Endothelial dysfunction induced by hydroxyl radicals – the hidden face of biodegradable Fe-based materials for coronary stents. In: Materials science & engineering. C, Materials for biological applications, Vol. 112, p. 110938 [1-11] (2020). doi:10.1016/j.msec.2020.110938.
2020
de Miranda Vasconcellos Vilela, Janice ; Dolmans, Marie-Madeleine ; Maruhashi, Emi ; Blackman, Marine ; Sonveaux, Pierre ; Miranda-Vilela, Ana Luisa ; Andrade Amorim, Christiani. Evidence of metabolic activity during low-temperature ovarian tissue preservation in different media.. In: Journal of assisted reproduction and genetics, Vol. 37, no. 10, p. 2477-2486 (2020). doi:10.1007/s10815-020-01935-y.
2020
Grasso, Debora ; Medeiros, Hyllana C ; Zampieri, Luca ; Bol, Vanesa ; Danhier, Pierre ; van Gisbergen, Marike W ; Bouzin, Caroline ; Brusa, Davide ; Grégoire, Vincent ; Smeets, Hubert ; Stassen, Alphons P ; Dubois, Ludwig ; Lambin, Philippe ; Dutreix, Marie ; Sonveaux, Pierre. Fitter mitochondria are associated with radioresistance in human head and neck SQD9 cancer cells. In: Frontiers in Pharmacology, Vol. 11, p. 263 [1-16] (2020). doi:10.3389/fphar.2020.00263.
2020
Colson, Arthur ; Depoix, Christophe ; Baldin, Paméla ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Hypoxia-inducible factor 2 alpha impairs human cytotrophoblast syncytialization: new insights in placental dysfunction and fetal growth restriction. In: The FASEB Journal, Vol. 34, no. 11, p. 15222-15235 (2020). doi:10.1096/fj.202001681R.
2020
Pothen, Lucie ; Yildiz, Halil ; Aydin, Selda ; Camboni, Alessandra ; Lambert, Michel ; Hainaut, Philippe ; Ebbo, Mikaël. Il vaut le bon Canteloup lui !. In: La Revue de médecine interne, Vol. 41, no. 1, p. 58-61 (2020). doi:10.1016/j.revmed.2019.06.009.
2020
Stelling, Elisabeth ; Ricke-Hoch, Melanie ; Erschow, Sergej ; Hoffmann, Steve ; Bergmann, Anke Katharina ; Heimerl, Maren ; Pietzsch, Stefan ; Battmer, Karin ; Haase, Alexandra ; Stapel, Britta ; Scherr, Michaela ; Balligand, Jean-Luc ; Binah, Ofer ; Hilfiker-Kleiner, Denise ; Lo, Cecilia W.. Increased prostaglandin-D2 in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation. In: PLoS biology, Vol. 18, no. 12, p. e3000739 [1-30] (2020). doi:10.1371/journal.pbio.3000739.
2020
Darius, Tom ; Vergauwen, Martial ; Smith, Thomas B ; Patel, Kamlesh ; Craps, Julie ; Joris, Virginie ; Aydin, Selda ; Ury, Benoît ; Buemi, Antoine ; De Meyer, Martine ; Nath, Jay ; Ludwig, Christian ; Dessy, Chantal ; Many, Marie-Christine ; Gianello, Pierre ; Mourad, Michel. Influence of different partial pressures of oxygen during continuous hypothermic machine perfusion in a pig kidney ischemia-reperfusion autotransplant model.. In: Transplantation, Vol. 104, no. 4, p. 731-743 (2020). doi:10.1097/TP.0000000000003051.
2020
Montiel, Virginie ; Bella, Ramona ; Michel, Lauriane ; Esfahani, Hrag ; De Mulder, Delphine ; Robinson, Emma L ; Deglasse, Jean-Philippe ; Tiburcy, Malte ; Chow, Pak Hin ; Jonas, Jean-Christophe ; Gilon, Patrick ; Steinhorn, Benjamin ; Michel, Thomas ; Beauloye, Christophe ; Bertrand, Luc ; Farah, Charlotte ; Dei Zotti, Flavia ; Debaix, Huguette ; Bouzin, Caroline ; Brusa, Davide ; Horman, Sandrine ; Vanoverschelde, Jean-Louis ; Bergmann, Olaf ; Gilis, Dimitri ; Rooman, Marianne ; Ghigo, Alessandra ; Geninatti-Crich, Simonetta ; Yool, Andrea ; Zimmermann, Wolfram H ; Roderick, H Llewelyn ; Devuyst, Olivier ; Balligand, Jean-Luc. Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide.. In: Science translational medicine, Vol. 12, no. 564, p. eaay2176 [1-16] (2020). doi:10.1126/scitranslmed.aay2176.
2020
Fourniols, Thibaut ; Bastien, Estelle ; Canevat, Alizée ; Feron, Olivier ; Préat, Véronique. Inhibition of colorectal cancer-associated fibroblasts by lipid nanocapsules loaded with acriflavine or paclitaxel.. In: International journal of pharmaceutics, Vol. 584, p. 119337 (2020). doi:10.1016/j.ijpharm.2020.119337 (Accepté/Sous presse).
2020
Thabault, Léopold ; Brisson, Lucie ; Brustenga, Chiara ; Martinez Gache, Santiago A ; Prévost, Julien ; Kozlova, Arina ; Spillier, Quentin ; Liberelle, Maxime ; Benyahia, Zohra ; Messens, Joris ; Copetti, Tamara ; Sonveaux, Pierre ; Frédérick, Raphaël. Interrogating the lactate dehydrogenase tetramerization site using (stapled) peptides.. In: Journal of medicinal chemistry, Vol. 63, no.9, p. 4628-4643 (2020). doi:10.1021/acs.jmedchem.9b01955.
2020
Collin, Amandine ; Lecocq, Marylène ; Noël, Sabrina ; Detry, Bruno ; Carlier, François ; Aboubakar Nana, Frank ; Bouzin, Caroline ; Leal, Teresinha ; Vermeersch, Marjorie ; De Rose, Virginia ; Regard, Lucile ; Martin, Clémence ; Burgel, Pierre-Régis ; Hoton, Delphine ; Verleden, Stijn ; Froidure, Antoine ; Pilette, Charles ; Gohy, Sophie. Lung immunoglobulin A immunity dysregulation in cystic fibrosis.. In: EBioMedicine, Vol. 60, p. 102974 [1-16] (2020). doi:10.1016/j.ebiom.2020.102974.
2020
De Miranda Capeloa, Tania Isabel ; Benyahia, Zohra ; Zampieri, Luca ; Blackman, Marine ; Sonveaux, Pierre. Metabolic and non-metabolic pathways that control cancer resistance to anthracyclines.. In: Seminars in cell & developmental biology, Vol. 98, p. 181-191 (2020). doi:10.1016/j.semcdb.2019.05.006.
2020
Mignion, Lionel ; Acciardo, Stefania ; Gourgue, Florian ; Joudiou, Nicolas ; Caignet, Xavier ; Goebbels, Rose-Marie ; Corbet, Cyril ; Feron, Olivier ; Bouzin, Caroline ; Cani, Patrice D. ; Machiels, Jean-Pascal ; Schmitz, Sandra ; Jordan, Bénédicte. Metabolic imaging using hyperpolarized pyruvate-lactate exchange assesses response or resistance to the EGFR inhibitor cetuximab in patient-derived HNSCC xenografts.. In: Clinical cancer research, Vol. 15, no. 26(8), p. 1932-1943 (2020). doi:10.1158/1078-0432.CCR-19-1369.
2020
Grasso, Debora ; Zampieri, Luca ; De Miranda Capeloa, Tania Isabel ; Van de Velde, Justine ; Sonveaux, Pierre. Mitochondria in cancer. In: Cell stress, Vol. 4, no. 6, p. 114-146 (2020).
2020
Zampieri, Luca ; Grasso, Debora ; Bouzin, Caroline ; Brusa, Davide ; Rossignol, Rodrigue ; Sonveaux, Pierre. Mitochondria participate in chemoresistance to cisplatin in human ovarian cancer cells. In: Molecular Cancer Research, Vol. 18, no. 9, p. 1379-1391 (2020). doi:10.1158/1541-7786.mcr-19-1145.
2020
Silverman, Edwin K ; Schmidt, Harald H H W ; Anastasiadou, Eleni ; Altucci, Lucia ; Angelini, Marco ; Badimon, Lina ; Balligand, Jean-Luc ; Benincasa, Giuditta ; Capasso, Giovambattista ; Conte, Federica ; Di Costanzo, Antonella ; Farina, Lorenzo ; Fiscon, Giulia ; Gatto, Laurent ; Gentili, Michele ; Loscalzo, Joseph ; Marchese, Cinzia ; Napoli, Claudio ; Paci, Paola ; Petti, Manuela ; Quackenbush, John ; Tieri, Paolo ; Viggiano, Davide ; Vilahur, Gemma ; Glass, Kimberly ; Baumbach, Jan. Molecular networks in Network Medicine: Development and applications.. In: Wiley interdisciplinary reviews. Systems biology and medicine, Vol. 12, no. 6, p. e1489 (2020). doi:10.1002/wsbm.1489.
2020
Payen, Valéry ; Mina, Erica ; Van Hee, Vincent ; Porporato, Paolo E ; Sonveaux, Pierre. Monocarboxylate transporters in cancer.. In: Molecular Metabolism, Vol. 33, p. 48-66 (2020). doi:10.1016/j.molmet.2019.07.006.
2020
Gourgue, Florian ; Mignion, Lionel ; Van Hul, Matthias ; Dehaen, Natacha ; Bastien, Estelle ; Payen, Valery ; Leroy, Baptiste ; Joudiou, Nicolas ; Vertommen, Didier ; Bouzin, Caroline ; Delzenne, Nathalie M. ; Gallez, Bernard ; Feron, Olivier ; Jordan, Bénédicte ; Cani, Patrice D.. Obesity and triple-negative-breast-cancer: Is apelin a new key target?. In: Journal of cellular and molecular medicine, Vol. 24, p. 10233-44 (2020). doi:10.1111/jcmm.15639.
2020
Triaille, Clément ; Vansteenkiste, Louise ; Constant, Manuel ; Ambroise, Jérôme ; Méric de Bellefon, Laurent ; Nzeusseu Toukap, Adrien ; Sokolova, Tatiana ; Galant, Christine ; Coulie, Pierre G. ; Carrasco, Javier ; Durez, Patrick ; Lauwerys, Bernard. Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity and TCR Signaling Pathways.. In: Frontiers in immunology, Vol. 11, p. 593083 [1-9] (2020). doi:10.3389/fimmu.2020.593083.
2020
Trempolec, Natalia ; Doix, Bastien ; Degavre, Charline ; Brusa, Davide ; Bouzin, Caroline ; Riant, Olivier ; Feron, Olivier. Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma. In: Cancers, Vol. 12, no. 3, p. pii:E545 (2020).
2020
Moens, Annick ; van der Woude, C Janneke ; Julsgaard, Mette ; Humblet, Evelien ; Sheridan, Juliette ; Baumgart, Daniel C ; Gilletta De Saint-Joseph, Cyrielle ; Nancey, Stéphane ; Rahier, Jean-François ; Bossuyt, Peter ; Cremer, Anneline ; Dewit, Sophie ; Eriksson, Carl ; Hoentjen, Frank ; Krause, Thomas ; Louis, Edouard ; Macken, Elisabeth ; Milenkovic, Zoran ; Nijs, Jochen ; Posen, Annelies ; Van Hootegem, Anneleen ; Van Moerkercke, Wouter ; Vermeire, Séverine ; Bar-Gil Shitrit, Ariella ; Ferrante, Marc. Pregnancy outcomes in inflammatory bowel disease patients treated with vedolizumab, anti-TNF or conventional therapy: results of the European CONCEIVE study.. In: Alimentary pharmacology & therapeutics, Vol. 51, no. 1, p. 129-138 (2020). doi:10.1111/apt.15539.
2020
Nicolaou, Orthodoxia ; Sokratous, Kleitos ; Makowska, Zuzanna ; Morell, María ; De Groof, Aurélie ; Montigny, Pauline ; Hadjisavvas, Andreas ; Michailidou, Kyriaki ; Oulas, Anastasis ; Spyrou, George M ; Demetriou, Christiana ; Alarcón-Riquelme, Marta E ; Psarellis, Savvas ; Kousios, Andreas ; Lauwerys, Bernard ; Kyriacou, Kyriacos. Proteomic analysis in lupus mice identifies Coronin-1A as a potential biomarker for lupus nephritis.. In: Arthritis research & therapy, Vol. 22, no. 1, p. 147 [1-16] (2020). doi:10.1186/s13075-020-02236-6.
2020
Descamps, Olivier ; De Sutter, Johan ; Mertens, Ann ; Wallemacq, Caroline ; Langlois, Michel ; Verhaegen, Ann ; Rietzschel, Ernst ; De Backer, Guy. Que retenir des recommandations de la Société Européenne de Cardiologie et de la Société Européenne d’Athérosclérose (2019) sur le traitement des dyslipidémies pour la prévention des maladies cardiovasculaires ? , collab. Balligand, Jean-Luc ; Beauloye, Christophe ; Chenu, Patrick ; Demeure, Fabian ; Hermans, Michel ; Persu, Alexandre. In: Louvain médical, Vol. 139, no.7, p. 396-404 (2020).
2020
Ward, Jennifer A ; Pinto-Fernandez, Adan ; Cornelissen, Loïc ; Bonham, Sarah ; Díaz-Sáez, Laura ; Riant, Olivier ; Huber, Kilian V M ; Kessler, Benedikt M ; Feron, Olivier ; Tate, Edward W. Re-evaluating the mechanism of action of α,β-unsaturated carbonyl DUB inhibitors b-AP15 and VLX1570: a paradigmatic example of unspecific protein crosslinking with Michael acceptor motif-containing drugs.. In: Journal of medicinal chemistry, Vol. 63, no. 7, p. 3756-3762 (2020). doi:10.1021/acs.jmedchem.0c00144.
2020
Vander Linden, Catherine ; Corbet, Cyril. Reconciling environment-mediated metabolic heterogeneity with the oncogene-driven cancer paradigm in precision oncology. In: Seminars in Cell and Developmental Biology, Vol. 98, p. 202-210 (2020). doi:10.1016/j.semcdb.2019.05.016.
2020
Dei Zotti, Flavia ; Verdoy, Roxane ; Brusa, Davide ; Lobysheva, Irina ; Balligand, Jean-Luc. Redox regulation of nitrosyl-hemoglobin in human erythrocytes.. In: Redox biology, Vol. 34, p. 101399 [1-10] (2020). doi:10.1016/j.redox.2019.101399.
2020
Baselet, Bjorn ; Driesen, Ronald B ; Coninx, Emma ; Belmans, Niels ; Sieprath, Tom ; Lambrichts, Ivo ; De Vos, Winnok H ; Baatout, Sarah ; Sonveaux, Pierre ; Aerts, An. Rosiglitazone protects endothelial cells from irradiation-induced mitochondrial dysfunction. In: Frontiers in Pharmacology, Vol. 11, p. 268 (2020). doi:10.3389/fphar.2020.00268.
2020
Godfraind, Theophile. Réflexion sur l'apport de l'intelligence artificielle à la pratique médicale . In: Louvain médical, Vol. 139, no.7, p. 428-435 (2020).
2020
Wérion, Alexis ; Belkhir, Leïla ; Perrot, Marie ; Schmit, Gregory ; Aydin, Selda ; Chen, Zhiyong ; Penaloza-Baeza, Andrea ; De Greef, Julien ; Yildiz, Halil ; Pothen, Lucie ; Yombi, Jean Cyr ; Dewulf, Joseph P. ; Scohy, Anaïs ; Gérard, Ludovic ; Wittebole, Xavier ; Laterre, Pierre-François ; Miller, Sara E ; Devuyst, Olivier ; Jadoul, Michel ; Morelle, Johann. SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule., collab. Cliniques universitaires Saint-Luc (CUSL) COVID-19 Research Group ; Gohy, Sophie. In: Kidney international, Vol. 98, no. 5, p. 1296-1307 (2020). doi:10.1016/j.kint.2020.07.019.
2020
Pothen, Lucie ; Yildiz, Halil ; De Greef, Julien ; Penaloza-Baeza, Andrea ; Beauloye, Christophe ; Belkhir, Leïla ; Yombi, Jean Cyr. Safety use of hydroxychloroquine and its combination with azithromycin in the context of Sars-CoV-2 outbreak: Clinical experience in a Belgian tertiary center. In: Travel Medicine and Infectious Disease, Vol. 36, p. 101788 [1-2] (2020). doi:10.1016/j.tmaid.2020.101788.
2020
Spillier, Quentin ; Ravez, Severine ; Unterlass, Judith ; Corbet, Cyril ; Degavre, Charline ; Feron, Olivier ; Frédérick, Raphaël. Structure–Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH). In: Pharmaceuticals, Vol. 13, no.2, p. 20 (2020). doi:10.3390/ph13020020.
2020
Montiel, Virginie ; Robert, Arnaud ; Robert, Annie ; Nabaoui, Anas ; Tourneux, Marie ; Morales Mestre, Natàlia ; Maerckx, Guillaume ; Laterre, Pierre-François ; Wittebole, Xavier. Surgical mask on top of high-flow nasal cannula improves oxygenation in critically ill COVID-19 patients with hypoxemic respiratory failure.. In: Annals of intensive care, Vol. 10, no. 1, p. 125 [1-7] (2020). doi:10.1186/s13613-020-00744-x.
2020
Corbet, Cyril ; Bastien, Estelle ; Santiago de Jesus, Joao Pedro ; Dierge, Emeline ; Martherus, Ruben ; Vander Linden, Catherine ; Doix, Bastien ; Degavre, Charline ; Guilbaud, Céline ; Petit, Laurenne ; Michiels, Carine ; Dessy, Chantal ; Larondelle, Yvan ; Feron, Olivier. TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells. In: Nature Communications, Vol. 11, no.1, p. 1 (2020). doi:10.1038/s41467-019-14262-3.
2020
Schoonjans, Céline A ; Mathieu, Barbara ; Joudiou, Nicolas ; Zampieri, Luca X ; Brusa, Davide ; Sonveaux, Pierre ; Feron, Olivier ; Gallez, Bernard. Targeting Endothelial Cell Metabolism by Inhibition of Pyruvate Dehydrogenase Kinase and Glutaminase-1.. In: Journal of clinical medicine, Vol. 9, no.10, p. 14pp (2020). doi:10.3390/jcm9103308.
2020
Michel, Lauriane ; Farah, Charlotte ; Balligand, Jean-Luc. The Beta3 Adrenergic Receptor in Healthy and Pathological Cardiovascular Tissues.. In: Cells, Vol. 9, no.12, p. 2584 [1-22] (2020). doi:10.3390/cells9122584.
2020
Parini, Paolo ; Altucci, Lucia ; Balligand, Jean-Luc ; Baumbach, Jan ; Ferdinandy, Péter ; Filetti, Sebastiano ; Maron, Bradley A. ; Petrillo, Enrico ; Silverman, Edwin K. ; Barabasi, Albert-Laszlo ; Loscalzo, Joseph. The Network Medicine Imperative and the Need for an International Network Medicine Consortium. In: The American Journal of Medicine, Vol. 133, no. 9, p. e451-e454 (2020). doi:10.1016/j.amjmed.2020.03.034.
2020
Haguet, Hélène ; Bouvy, Céline ; Delvigne, Anne-Sophie ; Modaffari, Elise ; Wannez, Adeline ; Sonveaux, Pierre ; Dogne, Jean-Michel ; Douxfils, Jonathan. The risk of arterial thrombosis in patients with chronic myeloid leukemia treated with second and third generation BCR-ABL tyrosine kinase inhibitors may be explained by their impact on endothelial cells: an in-vitro study. In: Frontiers in Pharmacology, Vol. 11, p. 1007 (2020). doi:10.3389/fphar.2020.01007.
2020
Dhooghe, Barbara ; Bouzin, Caroline ; Mottais, Angélique ; Hermans, Emmanuel ; Delion, Martial ; Panin, Nadtha ; Noël, Sabrina ; Leal, Teresinha. Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells. In: Biology Open, Vol. 9, no. 8, p. bio053116 [1-9] (2020). doi:10.1242/bio.053116.
2020
Schobesberger, Sophie ; Wright, Peter T ; Poulet, Claire ; Sanchez Alonso Mardones, Jose L ; Mansfield, Catherine ; Friebe, Andreas ; Harding, Sian E ; Balligand, Jean-Luc ; Nikolaev, Viacheslav O ; Gorelik, Julia. β-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes.. In: eLife, Vol. 9, p. e52221 [1-15] (2020). doi:10.7554/eLife.52221.
2019
Corso, Simona ; Isella, Claudio ; Bellomo, Sara E ; Apicella, Maria ; Durando, Stefania ; Migliore, Cristina ; Ughetto, Stefano ; D'Errico, Laura ; Menegon, Silvia ; Moya-Rull, Daniel ; Cargnelutti, Marilisa ; De Miranda Capeloa, Tania Isabel ; Conticelli, Daniela ; Giordano, Jessica ; Venesio, Tiziana ; Balsamo, Antonella ; Marchiò, Caterina ; Degiuli, Maurizio ; Reddavid, Rossella ; Fumagalli, Uberto ; De Pascale, Stefano ; Sgroi, Giovanni ; Rausa, Emanuele ; Baiocchi, Gian Luca ; Molfino, Sarah ; Pietrantonio, Filippo ; Morano, Federica ; Siena, Salvatore ; Sartore-Bianchi, Andrea ; Bencivenga, Maria ; Mengardo, Valentina ; Rosati, Riccardo ; Marrelli, Daniele ; Morgagni, Paolo ; Rausei, Stefano ; Pallabazzer, Giovanni ; De Simone, Michele ; Ribero, Dario ; Marsoni, Silvia ; Sottile, Antonino ; Medico, Enzo ; Cassoni, Paola ; Sapino, Anna ; Pectasides, Eirini ; Thorner, Aaron R ; Nag, Anwesha ; Drinan, Samantha D ; Wollison, Bruce M ; Bass, Adam J ; Giordano, Silvia. A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell-Intrinsic Transcriptional MSI Traits.. In: Cancer research, Vol. 79, no.22, p. 5884-5896 (2019). doi:10.1158/0008-5472.CAN-19-1166.
2019
Avnet, Sofia ; Baldini, Nicola ; Brisson, Lucie ; Pedersen, Stine Falsig ; Porporato, Paolo E ; Sonveaux, Pierre ; Szabadkai, Gyorgy ; Pastorekova, Silvia. Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer.. In: Frontiers in oncology, Vol. 9, p. 1332 (2019). doi:10.3389/fonc.2019.01332.
2019
Spillier, Quentin ; Vertommen, Didier ; Séverine Ravez ; Marteau, Romain ; THÉMANS, Quentin ; Corbet, Cyril ; Feron, Olivier ; Wouters, Johan ; Frédérick, Raphaël. Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation. In: Scientific Reports, Vol. 9, no. 1, p. 4737 (2019).
2019
Li, Sha ; Bouchy, Sandra ; Penninckx, Sebastien ; Marega, Riccardo ; Fichera, Ornella ; Gallez, Bernard ; Feron, Olivier ; Martinive, Philippe ; HEUSKIN, Anne-Catherine ; Michiels, Carine ; Lucas, Stéphane. Antibody-functionalized gold nanoparticles as tumor targeting radiosensitizers for proton therapy.. In: Nanomedicine (London, England), Vol. 14, p. 317-333 (2019). doi:10.2217/nnm-2018-0161.
2019
Cristallini, Caterina ; Barbani, Niccoletta ; Ventrelli, Letizia ; Summa, Chiara ; Filippi, Sara ; De Miranda Capeloa, Tania Isabel ; Vitale, Emanuela ; Albera, Carlo ; Messore, Barbara ; Giachino, Claudia. Biodegradable microparticles designed to efficiently reach and act on cystic fibrosis mucus barrier.. In: Materials science & engineering. C, Materials for biological applications, Vol. 95, no.95, p. 19-28 (2019). doi:10.1016/j.msec.2018.10.064.
2019
Balligand, Jean-Luc. Cancer and Peripartum Cardiomyopathy. In: JACC: CardioOncology, Vol. 1, no.2, p. 206-207 (2019). doi:10.1016/j.jaccao.2019.10.005.
2019
Ippolito, Luigi ; Morandi, Andrea ; Taddei, Maria Letizia ; Parri, Matteo ; Comito, Giuseppina ; Iscaro, Alessandra ; Raspollini, Maria Rosaria ; Magherini, Francesca ; Rapizzi, Elena ; Masquelier, Julien ; Muccioli, Giulio ; Sonveaux, Pierre ; Chiarugi, Paola ; Giannoni, Elisa. Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer.. In: Oncogene, Vol. 38, no. 27, p. 5339-5355 (2019). doi:10.1038/s41388-019-0805-7 (Accepté/Sous presse).
2019
André, Emilie ; De Pauw, Aurélia ; Verdoy, Roxane ; Brusa, Davide ; Bouzin, Caroline ; Timmermans, Aurélie ; Bertrand, Luc ; Balligand, Jean-Luc. Changes of Metabolic Phenotype of Cardiac Progenitor Cells During Differentiation: Neutral Effect of Stimulation of AMP-Activated Protein Kinase.. In: Stem cells and development, Vol. 28, no. 22, p. 1498-1513 (2019). doi:10.1089/scd.2019.0129.
2019
Brusa, Davide ; Balligand, Jean-Luc. Classification of the Immune Composition in the Tumor Infiltrate.. In: Methods in molecular biology (Clifton, N.J.), Vol. 1979, p. 305-315 (2019). doi:10.1007/978-1-4939-9240-9_19.
2019
Bernard, Antoine ; Chevrier, Sandy ; Beltjens, Françoise ; Dosset, Magalie ; Viltard, Etienne ; Lagrange, Anaïs ; Derangère, Valentin ; Oudot, Alexandra ; Ghiringhelli, François ; Collin, Bertrand ; Apetoh, Lionel ; Feron, Olivier ; Chen, Suzie ; Arnould, Laurent ; Végran, Frédérique ; Boidot, Romain. Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance. In: Cancer Research, Vol. 79, no. 23, p. 5958-5970 (2019). doi:10.1158/0008-5472.CAN-19-0840.
2019
Dierge, Emeline ; Feron, Olivier. Dealing with saturated and unsaturated fatty acid metabolism for anticancer therapy.. In: Current opinion in clinical nutrition and metabolic care, Vol. 22, no.6, p. 427-433 (2019). doi:10.1097/MCO.0000000000000601.
2019
Turkieh, Annie ; Porouchani, Sina ; Beseme, Olivia ; Chwastyniak, Maggy ; Amouyel, Philippe ; Lamblin, Nicolas ; Balligand, Jean-Luc ; Bauters, Christophe ; Pinet, Florence. Increased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity.. In: Cell death & disease, Vol. 10, no. 8, p. 608 [1-13] (2019). doi:10.1038/s41419-019-1857-x.
2019
Doix, Bastien ; Trempolec, Natalia ; Riant, Olivier ; Feron, Olivier. Low Photosensitizer Dose and Early Radiotherapy Enhance Antitumor Immune Response of Photodynamic Therapy-Based Dendritic Cell Vaccination.. In: Frontiers in oncology, Vol. 9, p. 811 (2019). doi:10.3389/fonc.2019.00811 (Accepté/Sous presse).
2019
Pothen, Lucie ; Aydin, Selda ; Camboni, Alessandra ; Hainaut, Philippe. Nephrotic syndrome without kidney injury revealing intravascular large B cell lymphoma.. In: BMJ case reports, Vol. 12, no. 6 (2019), p. e229359 [1-3] (2019). doi:10.1136/bcr-2019-229359.
2019
Baselet, Bjorn ; Sonveaux, Pierre ; Baatout, Sarah ; Aerts, An. Pathological effects of ionizing radiation: endothelial activation and dysfunction. In: Cellular and Molecular Life Sciences, Vol. 76, no. 4, p. 699-728 (2018).
2019
Balligand, Jean-Luc. Phosphatase regulatory subunits in beta-adrenergic signalling: a delicate balancing act.. In: Cardiovascular research, Vol. 115, no. 3, p. 477-478 (2019). doi:10.1093/cvr/cvy275.
2019
Wang, Hui ; Jiang, Heng ; Corbet, Cyril ; de Mey, Sven ; Law, Kalun ; Gevaert, Thierry ; Feron, Olivier ; De Ridder, Mark. Piperlongumine increases sensitivity of colorectal cancer cells to radiation: involvement of ROS production via dual inhibition of glutathione and thioredoxin systems. In: Cancer Letters, (2019). doi:10.1016/j.canlet.2019.02.034.
2019
Derouane, Françoise ; Lambert, Michel ; De Greef, Julien ; Malghem, Jacques ; Lecouvet, Frédéric. Primary infectious costochondritis due to Prevotella nigrescens in an immunocompetent patient: clinical and imaging findings.. In: Skeletal Radiology, Vol. 48, no. 8, p. 1305-1309 (2019). doi:10.1007/s00256-019-3148-0.
2019
Payen, Valéry L ; Zampieri, Luca ; Porporato, Paolo E ; Sonveaux, Pierre. Pro- and antitumor effects of mitochondrial reactive oxygen species.. In: Cancer metastasis reviews, Vol. 38, no. 1-2, p. 189-203 (2019). doi:10.1007/s10555-019-09789-2.
2019
Lévêque, Romain ; Corbet, Cyril ; Aubert, Léo ; Guilbert, Matthieu ; Lagadec, Chann ; Adriaenssens, Eric ; Duval, Jérémy ; Finetti, Pascal ; Birnbaum, Daniel ; Magné, Nicolas ; Chopin, Valérie ; Bertucci, François ; Le Bourhis, Xuefen ; Toillon, Robert-Alain. ProNGF increases breast tumor aggressiveness through functional association of TrkA with EphA2. In: Cancer Letters, Vol. 19, p. 30091-30096 (2019). doi:10.1016/j.canlet.2019.02.019 (Accepté/Sous presse).
2019
Milosevic, Tamara ; Vertenoeil, Gaëlle ; Payen, Valéry ; Sonveaux, Pierre ; Tulkens, Paul M. ; Constantinescu, Stefan N. ; Van Bambeke, Françoise. Prolonged inhibition and incomplete recovery of mitochondrial function in oxazolidinone-treated megakaryoblastic cell lines.. In: International journal of antimicrobial agents, Vol. 54, no. 5, p. 661-667 (2019). doi:10.1016/j.ijantimicag.2019.07.021.
2019
Strickaert Aurélie ; Corbet, Cyril ; Spinette SA ; Craciun L ; Dom G ; Andry G ; Larsimont D ; Wattiez R ; Dumont JE ; Feron, Olivier ; Maenhaut C. Reprogramming of energetic metabolism: increased expression and roles of pyruvate carboxylase in papillary thyroid cancer.. In: Thyroid, (2019). doi:10.1089/thy.2018.0435.
2019
Silva, Cláudia ; Correia-Branco, Ana ; Andrade, Nelson ; Ferreira, António Carlos ; Soares, Miguel Luz ; Sonveaux, Pierre ; Stephenne, Jean ; Martel, Fátima. Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines.. In: European journal of pharmacology, , p. 172533 (2019). doi:10.1016/j.ejphar.2019.172533.
2019
Scheinok, Samantha ; Driesschart, Benoit ; d'Hose, Donatienne ; Sonveaux, Pierre ; Robiette, Raphaël ; Gallez, Bernard. Synthesis and characterization of a 5-membered ring cyclic hydroxylamine coupled to triphenylphosphonium to detect mitochondrial superoxide by EPR spectrometry.. In: Free radical research, Vol. 53, no. 11-12, p. 1135-1143 (2019). doi:10.1080/10715762.2019.1692137.
2019
Feron, Olivier. The many metabolic sources of acetyl-CoA to support histone acetylation and influence cancer progression.. In: Annals of translational medicine, Vol. 7, no.Suppl 8, p. S277 (2019). doi:10.21037/atm.2019.11.140.
2019
Feron, Olivier. The many metabolic sources of acetyl-CoA to support histone acetylation and influence cancer progression.. In: Annals of translational medicine, Vol. 7, no.Suppl 8, p. S277 (2019). doi:10.21037/atm.2019.11.140.
2019
Feron, Olivier. The many metabolic sources of acetyl-CoA to support histone acetylation and influence cancer progression.. In: Annals of translational medicine, Vol. 7, no. Suppl 8, p. S277 (2019). doi:10.21037/atm.2019.11.140.
2019
Aboubakar Nana, Frank ; Lecocq, Marylène ; Ladjemi, Maha Zohra ; Detry, Bruno ; Dupasquier, Sébastien ; Feron, Olivier ; Massion, Pierre P. ; Sibille, Yves ; Pilette, Charles ; Ocak, Sebahat. Therapeutic Potential of Focal Adhesion Kinase Inhibition in Small Cell Lung Cancer. In: Molecular Cancer Therapeutics, Vol. 18, no. 1, p. 17-27 (2019). doi:10.1158/1535-7163.mct-18-0328.
2019
Vander Linden, Catherine ; Corbet, Cyril. Therapeutic targeting of cancer stem cells: integrating and exploiting the acidic niche. In: Frontiers in Oncology, (2019). doi:10.3389/fonc.2019.00159.
2019
Maack, Christoph ; Eschenhagen, Thomas ; Hamdani, Nazha ; Heinzel, Frank R ; Lyon, Alexander R ; Manstein, Dietmar J ; Metzger, Joseph ; Papp, Zoltán ; Tocchetti, Carlo G ; Birhan Yilmaz, M ; Anker, Stefan D ; Balligand, Jean-Luc ; Bauersachs, Johann ; Brutsaert, Dirk ; Carrier, Lucie ; Chlopicki, Stefan ; Cleland, John G ; de Boer, Rudolf A ; Dietl, Alexander ; Fischmeister, Rodolphe ; Harjola, Veli-Pekka ; Heymans, Stephane ; Hilfiker-Kleiner, Denise ; Holzmeister, Johannes ; de Keulenaer, Gilles ; Limongelli, Giuseppe ; Linke, Wolfgang A ; Lund, Lars H ; Masip, Josep ; Metra, Marco ; Mueller, Christian ; Pieske, Burkert ; Ponikowski, Piotr ; Ristic, Arsen ; Ruschitzka, Frank ; Seferovic, Petar M ; Skouri, Hadi ; Zimmermann, Wolfram H ; Mebazaa, Alexandre. Treatments targeting inotropy.. In: European heart journal, Vol. 40, no. 44, p. 3626-3644 (2019). doi:10.1093/eurheartj/ehy600 (Accepté/Sous presse).
2019
Choumessi Tchewonpi, Aphrodite ; Johanns, Manuel ; Beaufay, Claire ; Herent, Marie-France ; Stroobant, Vincent ; Vertommen, Didier ; Corbet, Cyril ; Jacobs, Roxane ; Herinckx, Gaëtan ; Steinberg, Gregory R ; Feron, Olivier ; Quetin-Leclercq, Joëlle ; Rider, Mark H.. Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia. In: Biochemical Journal, Vol. 476, no. 24, p. 3687-3704 (2019). doi:10.1042/BCJ20190326.
2018
Descamps, Olivier ; Van Caenegem, Olivier ; Hermans, Michel ; Balligand, Jean-Luc ; Beauloye, Christophe ; Bondue, Antoine ; Carlier, Stéphane ; Castermans, Emilie ; Chenot, Fabien ; Claeys, Marc ; De Block, Christophe ; De Leener, Anne ; De Meester, Antoine ; Demeure, Fabian ; De Raedt, Herbert ; Desmet, Walter ; Elegeert, Ivan ; Guillaume, Michel ; Hoffer, Etienne ; Kacenelenbogen, Raymond ; Lancellotti, Patrizio ; Langlois, Michel ; Leone, Attilio ; Mertens, Ann ; Paquot, Nicolas ; Vanakker, Olivier ; Vanoverschelde, Jean-Louis ; Verhaegen, Ann ; Vermeersch, Pieter ; Wallemacq, Caroline ; Rietzschel, Ernst. A Belgian consensus strategy to identify familial hypercholesterolaemia in the coronary care unit and its subsequent cascade screening and treatment: BEL-FaHST (The BELgium Familial Hypercholesterolaemia STrategy).. In: Atherosclerosis, Vol. 277, p. 369-376 (2018). doi:10.1016/j.atherosclerosis.2018.05.037.
2018
Gélinas, Roselle ; Mailleux, Florence ; Dontaine, Justine ; Bultot, Laurent ; Demeulder, Bénédicte ; Ginion, Audrey ; Daskalopoulos, Evangelos-Panagiotis ; Esfahani, Hrag ; Dubois-Deruy, Emilie ; Lauzier, Benjamin ; Gauthier, Chantal ; Olson, Aaron K ; Bouchard, Bertrand ; Des Rosiers, Christine ; Viollet, Benoit ; Sakamoto, Kei ; Balligand, Jean-Luc ; Vanoverschelde, Jean-Louis ; Beauloye, Christophe ; Horman, Sandrine ; Bertrand, Luc. AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.. In: Nature Communications, Vol. 9, no. 1, p. 374 [1-17] (2018). doi:10.1038/s41467-017-02795-4.
2018
Vanderstraeten, Jessica ; Derradji, Hanane ; Sonveaux, Pierre ; Colin, Ides ; Many, Marie-Christine ; Gérard, Anne-Catherine. Acute iodine deficiency induces a transient VEGF dependent microvascular response in mammary glands involving HIF-1, ROS and mTOR.. In: American journal of physiology. Cell physiology, Vol. 315, no. 4, p. C554-C557 (2018). doi:10.1152/ajpcell.00095.2017.
2018
Lourenço, Andre P ; Leite-Moreira, Adelino F ; Balligand, Jean-Luc ; Bauersachs, Johann ; Dawson, Dana ; de Boer, Rudolf A ; de Windt, Leon J ; Falcão-Pires, Inês ; Fontes-Carvalho, Ricardo ; Franz, Stefan ; Giacca, Mauro ; Hilfiker-Kleiner, Denise ; Hirsch, Emilio ; Maack, Christoph ; Mayr, Manuel ; Pieske, Burkert ; Thum, Thomas ; Tocchetti, Carlo G ; Brutsaert, Dirk L ; Heymans, Stephane. An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.. In: European Journal of Heart Failure, Vol. 20, no. 2, p. 216-227 (2018). doi:10.1002/ejhf.1059.
2018
Avnet, Sofia ; Baldini, Nicola ; Brisson, Lucie ; De Milito, Angelo ; Otto, Angela M ; Pastoreková, Silvia ; Porporato, Paolo E ; Szabadkai, Gyorgy ; Sonveaux, Pierre. Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism.. In: Frontiers in oncology, Vol. 8, p. 329 (2018). doi:10.3389/fonc.2018.00329.
2018
de Mey, Sven ; Jiang, Heng ; Corbet, Cyril ; Wang, H. ; Dufait, Inès ; Law, Kalun ; Bastien, Estelle ; Verovski, Valeri ; Gevaert, Thierry ; Feron, Olivier ; De Ridder, Mark. Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption. In: Frontiers in Pharmacology, Vol. 9, p. 1073 [1-12] (2018). doi:10.3389/fphar.2018.01073.
2018
Ladjemi, Maha Zohra ; Gras, Delphine ; Dupasquier, Sébastien ; Detry, Bruno ; Lecocq, Marylène ; Garulli, Céline ; Fregimilicka, Chantal ; Bouzin, Caroline ; Gohy, Sophie ; Chanez, Pascal ; Pilette, Charles. Bronchial Epithelial IgA Secretion Is Impaired in Asthma. Role of IL-4/IL-13. In: American Journal of Respiratory and Critical Care Medicine, Vol. 197, no. 11, p. 1396-1409 (2018). doi:10.1164/rccm.201703-0561oc.
2018
Balligand, Jean-Luc ; Farah, Charlotte. Can stress make you relax?. In: Cardiovascular Research, Vol. 114, no. 5, p. 643-644 (2018). doi:10.1093/cvr/cvy027.
2018
Hermida, Nerea ; Michel, Lauriane ; Esfahani, Hrag ; Dubois-Deruy, Emilie ; Hammond, Joanna ; Bouzin, Caroline ; Markl, Andreas ; Colin, Henri ; Van Steenbergen, Anne ; de Meester de Ravenstein, Christophe ; Beauloye, Christophe ; Horman, Sandrine ; Yin, Xiaoke ; Mayr, Manuel ; Balligand, Jean-Luc. Cardiac myocyte β3-adrenergic receptors prevent myocardial fibrosis by modulating oxidant stress-dependent paracrine signaling. In: European Heart Journal (English Edition), Vol. 39, no. 10, p. 888-898 (2018). doi:10.1093/eurheartj/ehx366.
2018
Lyoussi, Badiaa ; Cherkaoui-Tangi, Khadija ; Morel, Nicole ; Wibo, Maurice. Characterization of vascular dysregulation in meriones shawi after high-calorie diet feeding.. In: Clinical and Experimental Hypertension, Vol. 40, no.4, p. 353-362 (2018). doi:10.1080/10641963.2017.1377219.
2018
Scheinok, Samantha ; Levêque, Philippe ; Sonveaux, Pierre ; Driesschaert, Benoit ; Gallez, Bernard. Comparison of different methods for measuring the superoxide radical by EPR spectroscopy in buffer, cell lysates and cells.. In: Free radical research, p. 1-15 (2018). doi:10.1080/10715762.2018.1541321.
2018
Turkieh, Annie ; Fertin, Marie ; Bouvet, Marion ; Mulder, Paul ; Drobecq, Hervé ; Lemesle, Gilles ; Lamblin, Nicolas ; de Groote, Pascal ; Porouchani, Sina ; Chwastyniak, Maggy ; Beseme, Olivia ; Amouyel, Philippe ; Mouquet, Frédéric ; Balligand, Jean-Luc ; Richard, Vincent ; Bauters, Christophe ; Pinet, Florence. Expression and Implication of Clusterin in Left Ventricular Remodeling After Myocardial Infarction.. In: Circulation. Heart Failure, Vol. 11, no. 6, p. e004838 [1-13] (2018). doi:10.1161/CIRCHEARTFAILURE.117.004838.
2018
Lopez-Sublet, Marilucy ; Caratti di Lanzacco, Lorenzo ; Danser, A H Jan ; Lambert, Michel ; Elourimi, Ghassan ; Persu, Alexandre. Focus on increased serum angiotensin-converting enzyme level: From granulomatous diseases to genetic mutations.. In: Clinical Biochemistry, Vol. 59, p. 1-8 (2018). doi:10.1016/j.clinbiochem.2018.06.010.
2018
Pothen, Lucie ; D'Abadie, Philippe ; Kozyreff, Alexandra ; Mourin, Anne ; Coubeau, Laurent. Hibernoma mimicking liposarcoma. In: The Lancet, Vol. 392, no. 10143, p. 244 (2018). doi:10.1016/s0140-6736(18)31436-3.
2018
Corbet, Cyril ; Bastien, Estelle ; Draoui, Nihed ; Doix, Bastien ; Mignion, Lionel ; Jordan, Bénédicte ; Marchand, Arnaud ; Vanherck, Jean-Christophe ; Chaltin, Patrick ; Schakman, Olivier ; Becker, Holger M ; Riant, Olivier ; Feron, Olivier. Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.. In: Nature Communications, Vol. 9, no.1, p. 1208 (2018). doi:10.1038/s41467-018-03525-0.
2018
Vander Linden, Catherine ; Corbet, Cyril. Killing two birds with one stone: Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and radiosensitize tumors.. In: Molecular & Cellular Oncology, Vol. 5, no.4, p. 3 (2018). doi:10.1080/23723556.2018.1465016.
2018
Bettonville, Marie ; Weatherly, Kathleen ; d'Aria, Stefania ; Porporato, Paolo E ; Zhang, Jinyu ; Bousbata, Sabrina ; Sonveaux, Pierre ; Braun, Michel Y. Long-term antigen exposure deeply modifies metabolic requirements for T cell function. In: eLife, Vol. 7, p. e30938 (2018).
2018
van der Velden, Jolanda ; Gabriele Tocchetti, Carlo ; Varricchi, Gilda ; Bianco, Anna ; Sequeira, Vasco ; Hilfiker-Kleiner, Denise ; Hamdani, Nazha ; Leite-Moreira, Adelino ; Mayr, Manuel ; Falcão-Pires, Ines ; Thum, Thomas ; Dawson, Dana K ; Balligand, Jean-Luc ; Heymans, Stephane. Metabolic changes in hypertrophic cardiomyopathies: Scientific update from the Working Group of Myocardial Function of the European Society of Cardiology.. In: Cardiovascular Research, Vol. 114, no. 10, p. 1273-1280 (2018). doi:10.1093/cvr/cvy147.
2018
Joris, Virginie ; Gomez, Elvira Leon ; Menchi, Lisa ; Lobysheva, Irina ; Di Mauro, Vittoria ; Esfahani, Hrag ; Condorelli, Gianluigi ; Balligand, Jean-Luc ; Catalucci, Daniele ; Dessy, Chantal. MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium.. In: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, no. 10, p. 2345-2357 (2018). doi:10.1161/ATVBAHA.118.311145.
2018
Milosevic, Tamara ; Payen, Valéry ; Sonveaux, Pierre ; Muccioli, Giulio ; Tulkens, Paul M. ; Van Bambeke, Françoise. Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes.. In: Antimicrobial Agents and Chemotherapy, Vol. 62, no. 3, p. e01599-17 [1-17] (2018). doi:10.1128/AAC.01599-17.
2018
Farah, Charlotte ; Michel, Lauriane ; Balligand, Jean-Luc. Nitric oxide signalling in cardiovascular health and disease.. In: Nature Reviews Cardiology, Vol. 15, no. 5, p. 292-316 (2018). doi:10.1038/nrcardio.2017.224.
2018
Dei Zotti, Flavia ; Lobysheva, Irina ; Balligand, Jean-Luc. Nitrosyl-hemoglobin formation in rodent and human venous erythrocytes reflects NO formation from the vasculature in vivo.. In: PloS one, Vol. 13, no. 7, p. e0200352 [1-20] (2018). doi:10.1371/journal.pone.0200352.
2018
de Montjoye, Laurence ; Herman, Anne ; Dumoutier, Laure ; Lambert, Michel ; Tromme, Isabelle ; Baeck, Marie. Omalizumab in chronic spontaneous urticaria: A real-life experience of dose and intervals adjustments in Belgium.. In: Annals of allergy, asthma & immunology, Vol. 121, no. 5, p. 620-622 (2018). doi:10.1016/j.anai.2018.07.002.
2018
Montigaud, Yoann ; Ucakar, Bernard ; Krishnamachary, Balaji ; Bhujwalla, Zaver M ; Feron, Olivier ; Préat, Véronique ; Danhier, Fabienne ; Gallez, Bernard ; Danhier, Pierre. Optimized acriflavine-loaded lipid nanocapsules as a safe and effective delivery system to treat breast cancer.. In: International journal of pharmaceutics, Vol. 551, no.1-2, p. 322-328 (2018). doi:10.1016/j.ijpharm.2018.09.034.
2018
Duisit, Jérôme ; Amiel, Hadrien ; Wüthrich, Tsering ; Taddeo, Adriano ; Dedriche, Adeline ; Destoop, Vincent ; Pardoen, Thomas ; Bouzin, Caroline ; Joris, Virginie ; Magee, Derek ; Vögelin, Esther ; Harriman, David ; Dessy, Chantal ; Orlando, Giuseppe ; Behets Wydemans, Catherine ; Rieben, Robert ; Gianello, Pierre ; Lengelé, Benoît. Perfusion-decellularization of human ear grafts enables ECM-based scaffolds for auricular vascularized composite tissue engineering.. In: Acta Biomaterialia, Vol. 73, p. 339-354 (2018). doi:10.1016/j.actbio.2018.04.009.
2018
de Mey, Sven ; Jiang, Heng ; Wang, Hui ; Engels, Benedikt ; Gevaert, Thierry ; Dufait, Inès ; Feron, Olivier ; Aerts, Joeri ; Verovski, Valeri ; De Ridder, Mark. Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer.. In: Radiotherapy & Oncology, (2018). doi:10.1016/j.radonc.2018.04.003 (Accepté/Sous presse).
2018
Doix, Bastien ; Bastien, Estelle ; Rambaud, Alix ; Pinto, Adán ; Louis, Caroline ; Grégoire, Vincent ; Riant, Olivier ; Feron, Olivier. Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions.. In: Frontiers in oncology, Vol. 8, p. 393 (2018). doi:10.3389/fonc.2018.00393.
2018
Pouleur, Anne-Catherine ; Anker, Stefan ; Brito, Dulce ; Brosteanu, Oana ; Hasenclever, Dirk ; Casadei, Barbara ; Edelmann, Frank ; Filippatos, Gerasimos ; Gruson, Damien ; Ikonomidis, Ignatios ; Lhommel, Renaud ; Mahmod, Masliza ; Neubauer, Stefan ; Persu, Alexandre ; Gerber, Bernhard ; Piechnik, Stefan ; Pieske, Burkert ; Pieske-Kraigher, Elisabeth ; Pinto, Fausto ; Ponikowski, Piotr ; Senni, Michele ; Trochu, Jean-Noël ; Van Overstraeten, Nancy ; Wachter, Rolf ; Balligand, Jean-Luc. Rationale and design of a multicentre, randomized, placebo-controlled trial of mirabegron, a Beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease Beta3-left ventricular hypertrophy (Beta3-LVH).. In: ESC heart failure, Vol. 5, no. 5, p. 830-841 (2018). doi:10.1002/ehf2.12306.
2018
Balligand, Jean-Luc. Response to 'The potential multiple effects of beta3-adrenergic receptor agonists on the heart protection for patients with heart failure with preserved ejection fraction'.. In: European heart journal, Vol. 39, no. 48, p. 4288 (2018). doi:10.1093/eurheartj/ehy678.
2018
Corso, Simona ; Cargnelutti, Marilisa ; Durando, Stefania ; Menegon, Silvia ; Apicella, Maria ; Migliore, Cristina ; De Miranda Capeloa, Tania Isabel ; Ughetto, Stefano ; Isella, Claudio ; Medico, Enzo ; Bertotti, Andrea ; Sassi, Francesco ; Sarotto, Ivana ; Casorzo, Laura ; Pisacane, Alberto ; Mangioni, Monica ; Sottile, Antonino ; Degiuli, Maurizio ; Fumagalli, Uberto ; Sgroi, Giovanni ; Molfino, Sarah ; De Manzoni, Giovanni ; Rosati, Riccardo ; De Simone, Michele ; Marrelli, Daniele ; Saragoni, Luca ; Rausei, Stefano ; Pallabazzer, Giovanni ; Roviello, Franco ; Cassoni, Paola ; Sapino, Anna ; Bass, Adam ; Giordano, Silvia. Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts.. In: Neoplasia (New York, N.Y.), Vol. 20, no.5, p. 443-455 (2018). doi:10.1016/j.neo.2018.02.003.
2018
Corbet, Cyril. Stem Cell Metabolism in Cancer and Healthy Tissues: Pyruvate in the Limelight.. In: Frontiers in Pharmacology, Vol. 8, no.958, p. 1-7 (2018). doi:10.3389/fphar.2017.00958.
2018
Mailleux, Florence ; Beauloye, Christophe ; Balligand, Jean-Luc ; Horman, Sandrine ; Bertrand, Luc. Studying the Role of AMPK in Cardiac Hypertrophy and Protein Synthesis.. In: Methods in molecular biology (Clifton, N.J.), Vol. 1732, no.1, p. 321-342 (2018). doi:10.1007/978-1-4939-7598-3_21.
2018
Catry, Emilie ; Bindels, Laure B. ; Tailleux, Anne ; Lestavel, Sophie ; Neyrinck, Audrey M. ; Goossens, Jean-François ; Lobysheva, Irina ; Plovier, Hubert ; Essaghir, Ahmed ; Demoulin, Jean-Baptiste ; Bouzin, Caroline ; Pachikian, Barbara D. ; Cani, Patrice D. ; Staels, Bart ; Dessy, Chantal ; Delzenne, Nathalie M.. Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.. In: Gut, Vol. 67, no.2, p. 271-283 (2018). doi:10.1136/gutjnl-2016-313316.
2018
Frantz, Stefan ; Falcao-Pires, Ines ; Balligand, Jean-Luc ; Bauersachs, Johann ; Brutsaert, Dirk ; Ciccarelli, Michele ; Dawson, Dana ; de Windt, Leon J ; Giacca, Mauro ; Hamdani, Nazha ; Hilfiker-Kleiner, Denise ; Hirsch, Emilio ; Leite-Moreira, Adelino ; Mayr, Manuel ; Thum, Thomas ; Tocchetti, Carlo G ; van der Velden, Jolanda ; Varricchi, Gilda ; Heymans, Stephane. The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.. In: European Journal of Heart Failure, Vol. 20, no. 3, p. 445-459 (2018). doi:10.1002/ejhf.1138.
2017
Payen, Valéry ; Porporato, Paolo ; Danhier, Pierre ; Vazeille, Thibaut ; Blackman, Marine ; May, Bronislav H ; Niebes, Paul ; Sonveaux, Pierre. (+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice.. In: Frontiers in pharmacology, Vol. 8, p. 869 [1-11] (2017). doi:10.3389/fphar.2017.00869.
2017
Wartique, Lucie ; Pothen, Lucie ; Pirson, Nathalie ; Hermans, Michel ; Lambert, Michel ; Yildiz, Halil. An unusual cause of epidemic thyrotoxicosis.. In: Acta clinica Belgica, Vol. 72, no. 6, p. 451-453 (2017). doi:10.1080/17843286.2017.1309336.
2017
Baldini, Nicola ; De Milito, Angelo ; Feron, Olivier ; Gillies, Robert J ; Michiels, Carine ; Otto, Angela M ; Pastorekova, Silvia ; Perdersen, Stine F ; Porporato, Paolo ; Sonveaux, Pierre ; Supuran, Claudiu T ; Avnet, Sofia. Annual meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer. In: Frontiers in Pharmacology, Vol. 8, p. 411 [1-5] (2017). doi:10.3389/fphar.2017.00411.
2017
Wang, H. ; Bouzakoura, Soumaya ; de Mey, Sven ; Jiang, Heng ; Law, Kalun ; Dufait, Inès ; Corbet, Cyril ; Verovski, Valeri ; Gevaert, Thierry ; Feron, Olivier ; Van den Berge, Dirk ; Storme, Guy ; De Ridder, Mark. Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.. In: OncoTarget, (2017). doi:10.18632/oncotarget.16113 (Accepté/Sous presse).
2017
Duisit, Jérôme ; Maistriaux, Louis ; Taddeo, Adriano ; Orlando, Giuseppe ; Joris, Virginie ; Coche, Emmanuel ; Behets Wydemans, Catherine ; Lerut, Jan ; Dessy, Chantal ; Cossu, Giulio ; Vögelin, Esther ; Rieben, Robert ; Gianello, Pierre ; Lengelé, Benoît. Bioengineering a Human Face Graft: The Matrix of Identity.. In: Annals of Surgery, Vol. 266, no. 5, p. 754-764 (2017). doi:10.1097/SLA.0000000000002396.
2017
Corbet, Cyril ; Feron, Olivier. Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling.. In: Biochimica et Biophysica Acta : Reviews on Cancer, Vol. 1868, no. 1, p. 7-15 (2017). doi:10.1016/j.bbcan.2017.01.002.
2017
Stickaert, Aurélie ; Saiselet, Manuel ; Dom, Genevieve ; De Deken, Xavier ; Dumont, Jacques ; Feron, Olivier ; Sonveaux, Pierre ; Maenhaut, Carine. Cancer heterogeneity is not compatible with one unique cancer cell metabolic map. In: Oncogene, Vol. 36, no. 19, p. 2637-2642 (2017). doi:10.1038/onc.2016.411.
2017
Danhier, Pierre ; Banski, Piotr ; Payen, Valéry ; Grasso, Debora ; Ippolito, Luigi ; Sonveaux, Pierre ; Porporato, Paolo. Cancer metabolism in space and time: beyond the Warburg effect.. In: Biochimica et Biophysica Acta : international journal of biochemistry and biophysics, Vol. 1858, no. 8, p. 556–572 (2017). doi:10.1016/j.bbabio.2017.02.001.
2017
Balligand, Jean-Luc. Cardiac beta3-adrenergic receptors in the clinical arena: the end of the beginning.. In: European Journal of Heart Failure, Vol. 19, no. 4, p. 576-578 (2017). doi:10.1002/ejhf.784.
2017
Ravez, Séverine ; Spillier, Quentin ; Marteau, Romain ; Feron, Olivier ; Frédérick, Raphaël. Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy.. In: Journal of Medicinal Chemistry, Vol. 60, no. 4, p. 1227-1237 (2017). doi:10.1021/acs.jmedchem.6b01167.
2017
Lobysheva, Irina ; van Eeckhoudt, Sandrine ; Dei Zotti, Flavia ; Rifahi, Ahmad ; Pothen, Lucie ; Beauloye, Christophe ; Balligand, Jean-Luc. Clinical and biochemical data of endothelial function in Women Consuming Combined Contraceptives.. In: Data in Brief, Vol. 13, p. 46-52 (2017). doi:10.1016/j.dib.2017.05.019.
2017
Danhier, Pierre ; Deumer, Gladys ; Joudiou, Nicolas ; Bouzin, Caroline ; Levêque, Philippe ; Haufroid, Vincent ; Jordan, Bénédicte F ; Feron, Olivier ; Sonveaux, Pierre ; Gallez, Bernard. Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies.. In: OncoTarget, Vol. 8, no. 24, p. 38876-38885 (2017). doi:10.18632/oncotarget.17103.
2017
Baselet, Bjorn ; Azimzadeh, Omid ; Erbeldinger, Nadine ; Bakshi, Mayur V ; Dettmering, Till ; Janssen, Ann ; Ktitareva, Svetlana ; Lowe, Donna J ; Michaux, Arlette ; Quintens, Roel ; Raj, Kenneth ; Durante, Marco ; Fournier, Claudia ; Benotmane, Mohammed A ; Baatout, Sarah ; Sonveaux, Pierre ; Tapio, Soile ; Aerts, An. Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses.. In: Frontiers in Pharmacology, Vol. 8, p. 570 [1-15] (2017). doi:10.3389/fphar.2017.00570.
2017
De Pauw, Aurelia ; Andre, Emilie ; Sekkali, Belaid ; Bouzin, Caroline ; Esfahani, Hrag ; Barbier, Nicolas ; Loriot, Axelle ; De Smet, Charles ; Vanhoutte, Laetitia ; Moniotte, Stéphane ; Gerber, Bernhard ; di Mauro, Vittoria ; Catalucci, Daniele ; Feron, Olivier ; Hilfiker-Kleiner, Denise ; Balligand, Jean-Luc. Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction.. In: JCI insight, Vol. 2, no.12 (2017). doi:10.1172/jci.insight.91810.
2017
Apicella, M ; Migliore, C ; De Miranda Capeloa, Tania Isabel ; Menegon, S ; Cargnelutti, M ; Degiuli, M ; Sapino, A ; Sottile, A ; Sarotto, I ; Casorzo, L ; Cassoni, P ; De Simone, M ; Comoglio, P M ; Marsoni, S ; Corso, S ; Giordano, S. Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort.. In: Oncogene, Vol. 36, no.9, p. 1200-1210 (2017). doi:10.1038/onc.2016.283.
2017
Corbet, Cyril ; Feron, Olivier. Emerging roles of lipid metabolism in cancer progression.. In: Current Opinion in Clinical Nutrition and Metabolic Care, , p. 1 (2017). doi:10.1097/MCO.0000000000000381 (Accepté/Sous presse).
2017
van Steenberghe, Mathieu ; Schubert, Thomas ; Guiot , Yves ; Bouzin, Caroline ; Bollen, Xavier ; Gianello, Pierre. Enhanced vascular biocompatibility of decellularized xeno-/allogeneic matrices in a rodent model.. In: Cell and Tissue Banking, Vol. 18, no. 2, p. 249-262 (2017). doi:10.1007/s10561-017-9610-0.
2017
Bindels, Laure B. ; Porporato, Paolo ; Ducastel, Sarah ; Sboarina, Martina ; Neyrinck, Audrey M. ; Dewulf, Evelyne ; Feron, Olivier ; Lestavel, Sophie ; Cani, Patrice D. ; Staels, Bart ; Sonveaux, Pierre ; Delzenne, Nathalie M.. Ffar2 expression regulates leukaemic cell growth in vivo.. In: The British journal of cancer, Vol. 117, no. 9, p. 1336-1340 (2017). doi:10.1038/bjc.2017.307.
2017
Baselet, Bjorn ; Belmans, Niels ; Coninx, Emma ; Lowe, Donna ; Janssen, Ann ; Michaux, Arlette ; Tabury, Kevin ; Raj, Kenneth ; Quintens, Roel ; Benotmane, Mohammed A ; Baatout, Sarah ; Sonveaux, Pierre ; Aerts, An. Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose.. In: Frontiers in Pharmacology, Vol. 8, no. 213 (2017) (2017). doi:10.3389/fphar.2017.00213.
2017
Cacace, Andrea ; Sboarina, Martina ; Vazeille, Thibaut ; Sonveaux, Pierre. Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism. In: Oncogene : including Oncogene Reviews, Vol. 36, no. 15, p. 2074-2084 (2017). doi:10.1038/onc.2016.364.
2017
Lobysheva, Irina ; van Eeckhoudt, Sandrine ; Rifahi, Ahmad ; Pothen, Lucie ; Dei Zotti, Flavia ; Beauloye, Christophe ; Balligand, Jean-Luc. Heme-Nitrosylated Hemoglobin and Oxidative Stress in Women Consuming Combined Contraceptives. Clinical Application of the EPR Spectroscopy.. In: Free Radical Biology & Medicine, Vol. 108, p. 524-532 (2017). doi:10.1016/j.freeradbiomed.2017.03.039.
2017
Panisova, Elena ; Kery, Martin ; Sedlakova, Olga ; Brisson, Lucie ; Debreova, Michaela ; Sboarina, Martina ; Sonveaux, Pierre ; Pastorekova, Silvia ; Svastova, Eliska. Lactate stimulates CA IX expression in normoxic cancer cells.. In: OncoTarget, Vol. 8, p. 77819-77835 (2017). doi:10.18632/oncotarget.20836.
2017
Balligand, Jean-Luc ; Michel, Lauriane. Letter by Balligand and Michel Regarding Article, "Adrenergic Receptors in Individual Ventricular Myocytes: the Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent".. In: Circulation Research, Vol. 120, no. 12, p. e54-e55 (2017). doi:10.1161/CIRCRESAHA.117.310942.
2017
Lemma, Silvia ; Di Pompo, Gemma ; Porporato, Paolo ; Sboarina, Martina ; Russell, Shonagh ; Gillies, Robert J ; Baldini, Nicola ; Sonveaux, Pierre ; Avnet, Sofia. MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases.. In: Biochimica et Biophysica Acta : international journal of biochemistry and biophysics, Vol. 117, no. 9, p. 1336-1340 (2017). doi:10.1016/j.bbadis.2017.08.030.
2017
Vanhoutte, Laetitia ; Guilbaud, Céline ; Martherus, Sarkies-Ruben-Matthe ; Bouzin, Caroline ; Gallez, Bernard ; Dessy, Chantal ; Balligand, Jean-Luc ; Moniotte, Stéphane ; Feron, Olivier. MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression.. In: Scientific Reports, Vol. 7, p. 43951 [1-10] (2017). doi:10.1038/srep43951.
2017
HEUSKIN, Anne-Catherine ; Gallez, Bernard ; Feron, Olivier ; Martinive, Philippe ; Michiels, Carine ; Lucas, Stéphane. Metallic nanoparticles irradiated by low energy protons for radiation therapy: are there significant physical effects to enhance the dose delivery?. In: Medical Physics, Vol. 44, no. 8, p. 4299-4312 (2017). doi:10.1002/mp.12362.
2017
Gasparre, Giuseppe ; Rossignol, Rodrigue ; Sonveaux, Pierre. Mitochondria in cancer. In: BBA. Bioenergetics, Vol. 1858, no.8, p. 553-555 (2017). doi:10.1016/j.bbabio.2017.05.004.
2017
Payen, Valéry ; Hsu, Myriam ; Radecke, Kristin ; Wyart, Elisabeth ; Vazeille, Thibaut ; Bouzin, Caroline ; Porporato, Paolo ; Sonveaux, Pierre. Monocarboxylate transporter MCT1 promotes tumor metastasis independently of its activity as a lactate transporter.. In: Cancer Research, Vol. 77, no. 20, p. 5591-5601 (2017). doi:10.1158/0008-5472.CAN-17-0764.
2017
Roland, Thomas ; Yildiz, Halil ; Vandercam, Bernard ; Pothen, Lucie. Persistent fever and right hypochondrium pain. In: BMJ Case Reports, Vol. 2017, no. 1, p. 221254 (2017). doi:10.1136/bcr-2017-221254.
2017
Contino, Sabrina ; Porporato, Paolo ; Bird, Matthew ; Marinangeli, Claudia ; Opsomer, Rémi ; Sonveaux, Pierre ; Bontemps, Françoise ; Dewachter, Ilse ; Octave, Jean-Noël ; Bertrand, Luc ; Stanga, Serena ; Kienlen-Campard, Pascal. Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology.. In: Frontiers in Physiology, Vol. 8, p. 796 [1-11] (2017). doi:10.3389/fphys.2017.00796.
2017
Sonveaux, Pierre. ROS and radiotherapy: more we care.. In: OncoTarget, Vol. 8, no. 22, p. 35482-35483 (2017). doi:10.18632/oncotarget.16613.
2017
Van Hee, Vincent F ; Labar, Daniel ; Dehon, Gwenaël ; Grasso, Debora ; Gregoire, Vincent ; Muccioli, Giulio ; Frédérick, Raphaël ; Sonveaux, Pierre. Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors. In: OncoTarget, Vol. 8, no. 15, p. 24415-24428 (2017). doi:10.18632/oncotarget.14705.
2017
Van Steenbergen, Anne ; Balteau, Magali ; Ginion, Audrey ; Ferté, Laura ; Battault, Sylvain ; de Meester de Ravenstein, Christophe ; Balligand, Jean-Luc ; Daskalopoulos, Evangelos-Panagiotis ; Gilon, Patrick ; Despa, Florin ; Despa, Sanda ; Vanoverschelde, Jean-Louis ; Horman, Sandrine ; Koepsell, Hermann ; Berry, Gerard ; Hue, Louis ; Bertrand, Luc ; Beauloye, Christophe. Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart.. In: Scientific Reports, Vol. 7, p. 41166 [1-14] (2017). doi:10.1038/srep41166.
2017
Gomes, Clarissa P C ; Spencer, Helen ; Ford, Kerrie L ; Michel, Lauriane ; Baker, Andrew H ; Emanueli, Costanza ; Balligand, Jean-Luc ; Devaux, Yvan. The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease., collab. Cardiolinc network. In: Molecular Therapy - Nucleic Acids, Vol. 8, p. 494-507 (2017). doi:10.1016/j.omtn.2017.07.014.
2017
Hautem, Nicolas ; Morelle, Johann ; Sow, Amadou Tidiane ; Corbet, Cyril ; Feron, Olivier ; Goffin, Eric ; Huaux, François ; Devuyst, Olivier. The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis.. In: Journal of the American Society of Nephrology, Vol. 28, no. 7, p. 2038-2052 (2017). doi:10.1681/ASN.2016070729.
2017
Corbet, Cyril ; Feron, Olivier. Tumour acidosis: from the passenger to the driver's seat.. In: Nature Reviews. Cancer, Vol. 17, no.10, p. 577-593 (2017). doi:10.1038/nrc.2017.77.
2017
Bony, Emilie ; Mace, Yohan ; Pinto, Adán ; Delvaux, David ; Kiss, Robert ; Riant, Olivier ; Feron, Olivier ; Quetin-Leclercq, Joëlle. Validation of a SPE HPLC-UV method for the quantification of a new ER-specific photosensitizer OR-141 in blood serum using total error concept.. In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 141, p. 87-94 (2017). doi:10.1016/j.jpba.2017.03.060.
2017
Ravez, Séverine ; Corbet, Cyril ; Spillier, Quentin ; Dutu, Alice ; Robin, Anita D ; Mullarky, Edouard ; Cantley, Lewis Clayton ; Feron, Olivier ; Frédérick, Raphaël. α-Ketothioamide derivatives: a promising tool to interrogate the phosphoglycerate dehydrogenase (PHGDH).. In: Journal of Medicinal Chemistry, (2017). doi:10.1021/acs.jmedchem.6b01166 (Accepté/Sous presse).
2016
De Preter, Géraldine ; Deriemaeker, Caroline ; Danhier, Pierre ; Brisson, Lucie ; Cao Pham, Thanh Trang ; Grégoire, Vincent ; Jordan, Bénédicte ; Sonveaux, Pierre ; Gallez, Bernard. A Fast Hydrogen Sulfide-Releasing Donor Increases the Tumor Response to Radiotherapy. In: Molecular Cancer Therapeutics, Vol. 15, no. 1, p. 154-161 (2016). doi:10.1158/1535-7163.MCT-15-0691-T.
2016
Pinto Fernandez, Adan ; Mace, Yohan ; Drouet, Fleur ; Bony, Emilie ; Boidot, Romain ; Draoui, Nihed ; Lobysheva, Irina ; Corbet, Cyril ; Polet, Florence ; Martherus, Sarkies-Ruben-Matthe ; Deraedt, Quentin ; Rodríguez, Javier ; Lamy, ; Schicke, Olivier ; Delvaux, David ; Louis, Caroline ; Kiss, Robert ; Von Kriegsheim, Alexander ; Dessy, Chantal ; Elias, Benjamin ; Quetin-Leclercq, Joëlle ; Riant, Olivier ; Feron, Olivier. A new ER-specific photosensitizer unravels (1)O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT.. In: Oncogene, Vol. 35, no. 30, p. 3976-3985 (2016). doi:10.1038/onc.2015.474.
2016
Corbet, Cyril ; Pinto Fernandez, Adan ; Martherus, Sarkies-Ruben-Matthe ; Santiago de Jesus, Joao Pedro ; Polet, Florence ; Feron, Olivier. Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation.. In: Cell Metabolism, Vol. 24, no. 2, p. 311-323 (2016). doi:10.1016/j.cmet.2016.07.003.
2016
Balligand, Jean-Luc. Beta-Adrenergic Receptors Cooperate With Transcription Factors: The "STAT" of Their Union.. In: Circulation, Vol. 133, no. 1, p. 4-7 (2016). doi:10.1161/CIRCULATIONAHA.115.019860.
2016
Karmani, Linda ; Levêque, Philippe ; Bouzin, Caroline ; Bol, Anne ; Dieu, Marc ; Walrand, Stephan ; Vander Borght, Thierry ; Feron, Olivier ; Grégoire, Vincent ; Bonifazi, Davide ; Michiels, Carine ; Lucas, Stéphane ; Gallez, Bernard. Biodistribution of (125)I-labeled anti-endoglin antibody using SPECT/CT imaging: Impact of in vivo deiodination on tumor accumulation in mice.. In: Nuclear Medicine and Biology, Vol. 43, no. 7, p. 415-423 (2016). doi:10.1016/j.nucmedbio.2016.03.007.
2016
Balligand, Jean-Luc. Cardiac Salvage by Tweaking with Beta3-adrenergic Receptors. In: Cardiovascular Research, Vol. 111, no. 2, p. 128-133 (2016). doi:10.1093/cvr/cvw056.
2016
Baselet, Bjorn ; Rombouts, Charlotte ; Benotmane, Abderrafi Mohammed ; Baatout, Sarah ; Aerts, An. Cardiovascular diseases related to ionizing radiation: The risk of low-dose exposure (Review).. In: International Journal of Molecular Medicine, Vol. 38, no.6, p. 1623-1641 (2016). doi:10.3892/ijmm.2016.2777.
2016
Sonveaux, Pierre ; Maechler, Pierre ; Martinou, Jean-Claude. Channels and transporters in cell metabolism.. In: BBA - Molecular Cell Research, Vol. 1863, no. 10, p. 2359-2361 (2016). doi:10.1016/j.bbamcr.2016.06.001.
2016
Michiels, Carine ; Tellier, Céline ; Feron, Olivier. Cycling hypoxia: A key feature of the tumor microenvironment.. In: Biochimica et Biophysica Acta : Reviews on Cancer, (2016). doi:10.1016/j.bbcan.2016.06.004 (Accepté/Sous presse).
2016
Corbet, Cyril ; Ragelle, Héloïse ; Pourcelle, Vincent ; Vanvarenberg, Kevin ; Marchand-Brynaert, Jacqueline ; Préat, Véronique ; Feron, Olivier. Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method.. In: Journal of Controlled Release, Vol. 223, p. 53-63 (2016). doi:10.1016/j.jconrel.2015.12.020.
2016
De Preter, Géraldine ; Danhier, Pierre ; Porporato, Paolo ; Payen, Valéry ; Jordan, Bénédicte ; Sonveaux, Pierre ; Gallez, Bernard. Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro. In: Advances in Experimental Biology, Vol. 876, p. 209-214. doi:10.1007/978-1-4939-3023-4_26.
2016
De Preter, Géraldine ; Danhier, Pierre ; Porporato, Paolo ; Payen, Valery L ; Jordan, Benedicte ; Sonveaux, Pierre ; Gallez, Bernard. Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro.. In: Advances in Experimental Medicine and Biology, Vol. 876, p. 209-14 (2016). doi:10.1007/978-1-4939-3023-4_26.
2016
Romero, Miguel ; Leon-Gomez, Elvira ; Lobysheva, Irina ; Rath, Géraldine ; Dogné, Jean-Michel ; Feron, Olivier ; Dessy, Chantal. Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis.. In: PLoS One, Vol. 11, no.3, p. e0152579 (2016). doi:10.1371/journal.pone.0152579 (Accepté/Sous presse).
2016
Lemma, Silvia ; Sboarina, Martina ; Porporato, Paolo ; Zini, Nicoletta ; Sonveaux, Pierre ; Di Pompo, Gemma ; Baldini, Nicola ; Avnet, Sofia. Energy metabolism in osteoclast formation and activity.. In: The International Journal of Biochemistry & Cell Biology, Vol. 79, no.1, p. 168-180 (2016). doi:10.1016/j.biocel.2016.08.034.
2016
Vanhoutte, Laetitia ; Balligand, Jean-Luc ; Feron, Olivier ; Gerber, Bernhard ; Gallez, Bernard ; Po, Chrystelle ; Magat, Julie ; Moniotte, Stéphane. High field magnetic resonance imaging of rodents in cardiovascular research.. In: Basic Research in Cardiology, Vol. 111, p. 46 [1-20] (2016). doi:10.1007/s00395-016-0565-2.
2016
Dogné, Sophie ; Rath, Géraldine ; Jouret, François ; Caron, Nathalie ; Dessy, Chantal ; Flamion, Bruno. Hyaluronidase 1 deficiency preserves endothelial function and glycocalyx integrity in early streptozotocin-induced diabetes.. In: Diabetes, Vol. 65, no. 9, p. 2742-2753 (2016). doi:10.2337/db15-1662.
2016
Polet, Florence ; Martherus, Sarkies-Ruben-Matthe ; Corbet, Cyril ; Pinto Fernandez, Adan ; Feron, Olivier. Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells.. In: Oncotarget, Vol. 7, no. 29, p. 46371-46383 (2016). doi:10.18632/oncotarget.6426.
2016
De Preter, Géraldine ; Neveu, Marie-Aline ; Danhier, Pierre ; Brisson, Lucie ; Payen, Valéry ; Porporato, Paolo ; Jordan, Bénédicte ; Sonveaux, Pierre ; Gallez, Bernard. Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation. In: OncoTarget, Vol. 7, no. 3, p. 2910-2920 (2016). doi:10.18632/oncotarget.6272.
2016
Craps, Julie ; Joris, Virginie ; De Jongh, Britt ; Sonveaux, Pierre ; Horman, Sandrine ; Lengelé, Benoît ; Bertrand, Luc ; Many, Marie-Christine ; Colin, Idesbald ; Gerard, Anne-Catherine. Involvement of mTOR and regulation by AMPK in TSH-independent iodine deficiency-induced thyroid microvascular activation. In: Endocrinology, Vol. 157, no. 6, p. 2545-2559 (2016). doi:10.1210/en.2015-1911.
2016
Vanderstraeten, Jessica ; Derradji, H ; Craps, Julie ; Sonveaux, Pierre ; Colin, Idesbald ; Many, Marie-Christine ; Gerard, Anne-Catherine. Iodine deficiency induces a VEGF-dependent microvascular response in salivary glands and in the stomach. In: Histology and Histopathology : cellular and molecular biology, Vol. 31, no. 8, p. 897-909 (2016). doi:10.14670/HH-11-727.
2016
Li, Sha ; Penninckx, Sébastien ; Karmani, Linda ; HEUSKIN, Anne-Catherine ; Watillon , Kassandra ; Marega , Riccardo ; Zola, Jerome ; Corvaglia, Valentina ; Genard, Géraldine ; Gallez, Bernard ; Feron, Olivier ; Martinive , Philippe ; Bonifazi , Davide ; Michiels, Carine ; Lucas, Stéphane. LET-dependent radiosensitization effects of gold nanoparticles for proton irradiation. In: Nanotechnology, Vol. 27, no.45, p. 455101 [1-9] (2016). doi:10.1088/0957-4484/27/45/455101.
2016
Brisson, Lucie ; Banski, Piotr ; Sboarina, Martina ; Dethier, Coralie ; Danhier, Pierre ; Fontenille, Marie-Joséphine ; Van Hee, Vincent F ; Vazeille, Thibaut ; Tardy, Morgane ; Falces Ramos, Jorge ; Bouzin, Caroline ; Porporato, Paolo ; Frédérick, Raphaël ; Michiels, Carine ; Copetti, Tamara ; Sonveaux, Pierre. Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer.. In: Cancer Cell, Vol. 30, no.3, p. 418-431 (2016). doi:10.1016/j.ccell.2016.08.005.
2016
Perez Escuredo, Jhudit ; Dadhich, Rajesh Kumar ; Dhup, Suveera ; Cacace, Andrea ; Van Hee, Vincent F ; De Saedeleer, Christophe ; Sboarina, Martina ; Rodriguez, Fabien ; Fontenille, Marie-Joséphine ; Brisson, Lucie ; Porporato, Paolo ; Sonveaux, Pierre. Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.. In: Cell Cycle, Vol. 15, no. 1, p. 72-83 (2016). doi:10.1080/15384101.2015.1120930.
2016
Clouet, Sophie ; Di Pietrantonio, Larissa ; Daskalopoulos, Evangelos-Panagiotis ; Esfahani, Hrag ; Horckmans, Michael ; Vanorlé, Marion ; Lemaire, Anne ; Balligand, Jean-Luc ; Beauloye, Christophe ; Boeynaems, Jean-Marie ; Communi, Didier. Loss of mouse P2Y6 nucleotide receptor is associated with physiological macrocardia and amplified pathological cardiac hypertrophy.. In: Journal of Biological Chemistry, Vol. 291, no. 30, p. 15841-15852 (2016). doi:10.1074/jbc.M115.684118.
2016
Payen, Valéry ; Porporato, Paolo ; Baselet, Bjorn ; Sonveaux, Pierre. Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway. In: Cellular and Molecular Life Sciences, Vol. 73, no. 7, p. 1333-1348 (2016). doi:10.1007/s00018-015-2098-5.
2016
Porporato, Paolo ; Payen, Valéry ; Baselet, Bjorn ; Sonveaux, Pierre. Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism. In: Cellular and Molecular Life Sciences, Vol. 73, no. 7, p. 1349-1363 (2016). doi:10.1007/s00018-015-2100-2.
2016
Baldini, Nicola ; Sonveaux, Pierre ; De Milito, Angelo ; Supuran, Claudiu T ; Otto, Angela M ; Stock, Christian M ; Pedersen, Stine F ; Favicchio, Rosy ; Avnet, Sofia. Metabolism and microenvironment in cancer plasticity. In: Cancer & Metabolism, Vol. 4, no. Suppl. 1, p. 1 (2016).
2016
Perez Escuredo, Jhudit ; Van Hee, Vincent F ; Sboarina, Martina ; Falces Ramos, Jorge ; Payen, Valéry ; Pellerin, Luc ; Sonveaux, Pierre. Monocarboxylate transporters in the brain and in cancer. In: BBA - Molecular Cell Research, Vol. 1863, p. 2481-2497 (2016). doi:10.1016/j.bbamcr.2016.03.013.
2016
Neveu, Marie-Aline ; De Preter, Géraldine ; Joudiou, Nicolas ; Bol, Anne ; Brender , Jeffery R. ; Saito , Keita ; Kishimoto , Shun ; Grégoire, Vincent ; Jordan, Bénédicte ; Krishna , Murali C. ; Feron, Olivier ; Gallez, Bernard. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models. In: OncoTarget, Vol. 7, no.49, p. 81741-81749 (2016). doi:10.18632/oncotarget.13176.
2016
Neveu, Marie-Aline ; De Preter, Géraldine ; Marchand, Valérie ; Bol, Anne ; Brender, Jeffery R ; Saito, Keita ; Kishimoto, Shun ; Porporato, Paolo ; Sonveaux, Pierre ; Grégoire, Vincent ; Feron, Olivier ; Jordan, Bénédicte ; Krishna, Murali C ; Gallez, Bernard. Multimodality imaging identifies distinct metabolic profiles in vitro and in vivo. In: NeoPlasia : an international journal of oncology research, Vol. 18, no. 12, p. 742-752 (2016). doi:10.1016/j.neo.2016.10.010.
2016
Michel, Lauriane ; Balligand, Jean-Luc. New and Emerging Therapies and Targets: Beta-3 Agonists.. In: Handbook of Experimental Pharmacology, (2016). doi:10.1007/164_2016_88 (Accepté/Sous presse).
2016
Mignion, Lionel ; Danhier, Pierre ; Magat, Julie ; Porporato, Paolo ; Masquelier, Julien ; Grégoire, Vincent ; Muccioli, Giulio ; Sonveaux, Pierre ; Gallez, Bernard ; Jordan, Bénédicte. Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.. In: International Journal of Cancer, Vol. 138, no. 8, p. 2043-2049 (2016). doi:10.1002/ijc.29932.
2016
Catry, Emilie ; Neyrinck, Audrey M. ; Lobysheva, Irina ; Pachikian, Barbara D. ; Van Hul, Matthias ; Cani, Patrice D. ; Dessy, Chantal ; Delzenne, Nathalie M.. Nutritional depletion in n-3 PUFA in apoE knock-out mice: a new model of endothelial dysfunction associated with fatty liver disease.. In: Molecular Nutrition & Food Research, Vol. 60, no. 10, p. 2198-2207 (2016). doi:10.1002/mnfr.201500930.
2016
De Pauw, Aurélia ; Massion, Paul ; Sekkali, Belaid ; André, Emilie ; Dubroca, Caroline ; Kmecova, Jana ; Bouzin, Caroline ; Friart, Ann ; Sibille, Catherine ; Gilon, Patrick ; De Mulder, Delphine ; Esfahani, Hrag ; Strapart, Adrien ; Martherus, Sarkies-Ruben-Matthe ; Payen, Valéry ; Sonveaux, Pierre ; Brouckaert, Peter ; Janssens, Stefan ; Balligand, Jean-Luc. Paracrine Nitric Oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble Guanylyl Cyclase/cyclic-GMP and Wnt/β-catenin inhibition.. In: Cardiovascular Research, Vol. 112, no. 1, p. 478-490 (2016). doi:10.1093/cvr/cvw196.
2016
Wérion, Alexis ; Joris, Virginie ; Hepp, Michael ; Papasokrati, Lida ; Marique, Lancelot ; de Ville de Goyet, Christine ; Van Regemorter, Victoria ; Mourad, Michel ; Lengelé, Benoît ; Daumerie, Chantal ; Marbaix, Etienne ; Brichard, Sonia ; Many, Marie-Christine ; Craps, Julie. Pioglitazone, a PPARγ agonist, upregulates the expression of caveolin-1 and catalase, essential for thyroid cell homeostasis. A clue to the pathogenesis of Hashimoto's thyroiditis.. In: Thyroid, Vol. 26, no. 9, p. 1320-1331 (2016). doi:10.1089/thy.2015.0625.
2016
Fruytier, Anne-Catherine ; Le Duff , Cécile S. ; Po, Chrystelle ; Magat, Julie ; Bouzin, Caroline ; Neveu, Marie-Aline ; Feron, Olivier ; Jordan, Bénédicte ; Gallez, Bernard. The Blood Flow Shutdown Induced by Combretastatin A4 Impairs Gemcitabine Delivery in a Mouse Hepatocarcinoma. In: Frontiers in Pharmacology, Vol. 7, p. 506 [1-8] (2016). doi:10.3389/fphar.2016.00506.
2016
Chano, Tokuhiro ; Avnet, Sofia ; Kusuzali, Katsuyuki ; Bonuccelli, Gloria ; Sonveaux, Pierre ; Rotili, Dante ; Mai, Antonello ; Baldini, Nicola. Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells. In: American Journal of Cancer Research, Vol. 6, no. 4, p. 859-875 (2016).
2016
Porporato, Paolo. Understanding cachexia as a cancer metabolism syndrome. In: Oncogenesis, . doi:10.1038/oncsis.2016.3 (Accepté/Sous presse).
2016
Madlala, Hlengiwe P ; Metzinger, Thomas ; van Heerden, Fanie R ; Musabayane, Cephas T ; Mubagwa, Kanigula ; Dessy, Chantal. Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects.. In: PLoS One, Vol. 11, no. 1, p. e0147395 [1-16] (2016). doi:10.1371/journal.pone.0147395.
2016
Romero, Miguel ; Jimenez, Rosario ; Toral, Marta ; Leon-Gomez, Elvira ; Gomez-Guzman, Manuel ; Sanchez, Manuel ; Zarzuelo, Maria Jose ; Rodriguez-Gomez, Isabel ; Rath, Geraldine ; Tamargo, Juan ; Perez-Vizcaino, Francisco ; Dessy, Chantal ; Duarte, Juan. Vascular and central activation of Peroxisome Proliferator-Activated Receptor-β attenuates angiotensin II-induced hypertension. Role of RGS-5.. In: The Journal of Pharmacology and Experimental Therapeutics, Vol. 358, no. 1, p. 151-163 (2016). doi:10.1124/jpet.116.233106.
2015
Buescher, Joerg M ; Antoniewicz, Maciek R ; Boros, Laszlo G ; Burgess, Shawn C ; Brunengraber, Henri ; Clish, Clary B ; DeBerardinis, Ralph J ; Feron, Olivier ; Frezza, Christian ; Ghesquiere, Bart ; Gottlieb, Eyal ; Hiller, Karsten ; Jones, Russell G ; Kamphorst, Jurre J ; Kibbey, Richard G ; Kimmelman, Alec C ; Locasale, Jason W ; Lunt, Sophia Y ; Maddocks, Oliver Dk ; Malloy, Craig ; Metallo, Christian M ; Meuillet, Emmanuelle J ; Munger, Joshua ; Nöh, Katharina ; Rabinowitz, Joshua D ; Ralser, Markus ; Sauer, Uwe ; Stephanopoulos, Gregory ; St-Pierre, Julie ; Tennant, Daniel A ; Wittmann, Christoph ; Vander Heiden, Matthew G ; Vazquez, Alexei ; Vousden, Karen ; Young, Jamey D ; Zamboni, Nicola ; Fendt, Sarah-Maria. A roadmap for interpreting (13)C metabolite labeling patterns from cells.. In: Current Opinion in Biotechnology, Vol. 34, p. 189-201 (2015). doi:10.1016/j.copbio.2015.02.003.
2015
Desmet, Celine ; Lafosse, Aurore ; Veriter, Sophie ; Porporato, Paolo ; Sonveaux, Pierre ; Dufrane, Denis ; Levêque, Philippe ; Gallez, Bernard. Application of Electron Paramagnetic Resonance (EPR) Oximetry to Monitor Oxygen in Wounds in Diabetic Models.. In: PLoS One, Vol. 10, no. 12, p. e0144914 [1-16] (2015). doi:10.1371/journal.pone.0144914.
2015
Trappanese, Danielle M ; Liu, Yuchuan ; McCormick, Ryan C ; Cannavo, Alessandro ; Nanayakkara, Gayani ; Baskharoun, Marina M ; Jarrett, Harish ; Woitek, Felix J ; Tillson, D Michael ; Dillon, A Ray ; Recchia, Fabio A ; Balligand, Jean-Luc ; Houser, Steven R ; Koch, Walter J ; Dell'Italia, Louis J ; Tsai, Emily J. Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy.. In: Basic Research in Cardiology, Vol. 110, no. 1, p. 456 [1-26] (2015). doi:10.1007/s00395-014-0456-3.
2015
Chereddy, Kiran Kumar ; Lopes, Alessandra ; Koussoroplis, Salomé ; Payen, Valéry ; Moia, Claudia ; Zhu, Huijun ; Sonveaux, Pierre ; Carmeliet, Peter ; des Rieux, Anne ; Vandermeulen, Gaëlle ; Préat, Véronique. Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds.. In: Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 11, no. 8, p. 1975-1984 (2015). doi:10.1016/j.nano.2015.07.006.
2015
Payen, Valéry ; Brisson, Lucie ; Dewhirst, Mark W ; Sonveaux, Pierre. Common responses of tumors and wounds to hypoxia.. In: The Cancer Journal, Vol. 21, no. 2, p. 75-87 (2015). doi:10.1097/PPO.0000000000000098.
2015
Tellier, Céline ; Desmet, Déborah ; Petit, Laurenne ; Finet, Laure ; Graux, Carlos ; Raes, Martine ; Feron, Olivier ; Michiels, Carine. Cycling hypoxia induces a specific amplified inflammatory phenotype in endothelial cells and enhances tumor-promoting inflammation in vivo.. In: NeoPlasia : an international journal of oncology research, Vol. 17, no. 1, p. 66-78 (2015). doi:10.1016/j.neo.2014.11.003.
2015
Macé, Yohan ; Bony, Emilie ; Delvaux, David ; Pinto Fernandez, Adan ; Mathieu, Véronique ; Kiss, Robert ; Feron, Olivier ; Quetin-Leclercq, Joëlle ; Riant, Olivier. Cytotoxic activities and metabolic studies of new combretastatin analogues. In: Medicinal Chemistry Research, Vol. 24, no. 8, p. 3143-3156 (2015). doi:10.1007/s00044-015-1363-3.
2015
Gallina, Clara ; De Miranda Capeloa, Tania Isabel ; Saviozzi, Silvia ; Accomasso, Lisa ; Catalano, Federico ; Tullio, Francesca ; Martra, Gianmario ; Penna, Claudia ; Pagliaro, Pasquale ; Turinetto, Valentina ; Giachino, Claudia. Human mesenchymal stem cells labelled with dye-loaded amorphous silica nanoparticles: long-term biosafety, stemness preservation and traceability in the beating heart.. In: Journal of nanobiotechnology, Vol. 13, no.77, p. 77 (2015). doi:10.1186/s12951-015-0141-1.
2015
Danhier, Pierre ; Magat, Julie ; Levêque, Philippe ; De Preter, Géraldine ; Porporato, Paolo ; Bouzin, Caroline ; Jordan, Bénédicte ; Demeur, Gladys ; Haufroid, Vincent ; Feron, Olivier ; Sonveaux, Pierre ; Gallez, Bernard. In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance.. In: NMR in Biomedicine, Vol. 28, no. 3, p. 367-375 (2015). doi:10.1002/nbm.3259.
2015
Ragelle, Héloïse ; Colombo, Stefano ; Pourcelle, Vincent ; Vanvarenberg, Kevin ; Vandermeulen, Gaëlle ; Bouzin, Caroline ; Marchand-Brynaert, Jacqueline ; Feron, Olivier ; Foged, Camilla ; Préat, Véronique. Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight. In: Journal of Controlled Release, Vol. 211, p. 1-9 (2015). doi:10.1016/j.jconrel.2015.05.274.
2015
Craps, Julie ; Wilvers, Christine ; Joris, Virginie ; De Jongh, Britt ; Vanderstraeten, J ; Lobysheva, Irina ; Balligand, Jean-Luc ; Sonveaux, Pierre ; Gilon, Patrick ; Many, Marie-Christine ; Gérard, Anne-Catherine ; Colin, Idesbald. Involvement of nitric oxide in iodine deficiency-induced microvascular remodeling in the thyroid gland: role of nitric oxide synthase 3 and ryanodine receptors.. In: Endocrinology, Vol. 156, no. 2, p. 707-720 (2015). doi:10.1210/en.2014-1729.
2015
Balligand, Jean-Luc. KLF6 orchestrates cardiac myocyte-to-fibroblast communication: 'He who has ears to hear, let him hear'.. In: Cardiovascular Research, Vol. 107, no. 4, p. 397-399 (2015). doi:10.1093/cvr/cvv189.
2015
Van Hee, Vincent ; Perez Escuredo, Jhudit ; Cacace, Andrea ; Copetti, Tamara ; Sonveaux, Pierre. Lactate does not activate NF-κB in oxidative tumor cells.. In: Frontiers in Pharmacology, Vol. 6, p. 228 (2015). doi:10.3389/fphar.2015.00228.
2015
Arregi, Igor ; Falces Ramos, Jorge ; Olazabal-Herrero, Anne ; Alonso-Mariño, Marián ; Taneva, Stefka G. ; Rodríguez, José A. ; Urbaneja, María A. ; Bañuelos, Sonia ; Larijani, Banafshe. Leukemia-Associated Mutations in Nucleophosmin Alter Recognition by CRM1: Molecular Basis of Aberrant Transport. In: PLoS One, Vol. 10, no.6, p. e0130610 (2015). doi:10.1371/journal.pone.0130610.
2015
Gurevich , Michael ; Guy-Viterbo, Vanessa ; Janssen, Magdalena ; Stéphenne, Xavier ; Smets, Françoise ; Sokal, Etienne ; Lefebvre, Chantal ; Balligand, Jean-Luc ; Pirotte, Thierry ; Veyckemans, Francis ; Clapuyt, Philippe ; Menten, Renaud ; Dumitriu, Dana Loana ; Danse, Etienne ; Annet, Laurence ; Clement de Clety, Stephan ; Detaille , Thierry ; Latinne, Dominique ; Sempoux, Christine ; Laterre, Pierre-François ; De Magnée, Catherine ; Lerut, Jan ; Reding, Raymond. Living Donor Liver Transplantation in Children: Surgical and Immunological Results in 250 Recipients at Université Catholique de Louvain.. In: Annals of Surgery, Vol. 262, no. 6, p. 1141-1149 (2015). doi:10.1097/SLA.0000000000001094.
2015
Horckmans, Michael ; Esfahani, Hrag ; Beauloye, Christophe ; Clouet, Sophie ; di Pietrantonio, Larissa ; Robaye, Bernard ; Balligand, Jean-Luc ; Boeynaems, Jean-Marie ; Dessy, Chantal ; Communi, Didier. Loss of Mouse P2Y4 Nucleotide Receptor Protects against Myocardial Infarction through Endothelin-1 Downregulation.. In: Journal of Immunology, Vol. 194, no. 4, p. 1874-1881 (2015). doi:10.4049/jimmunol.1401364.
2015
Corbet, Cyril ; Feron, Olivier. Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.. In: Current Opinion in Clinical Nutrition and Metabolic Care, Vol. 18, no. 4, p. 346-353 (2015). doi:10.1097/MCO.0000000000000178.
2015
Lucas, Stéphane ; Feron, Olivier ; Gallez, Bernard ; Masereel, Bernard ; Michiels, Carine ; Vander Borght, Thierry. Monte Carlo Calculation of Radioimmunotherapy with (90)Y-, (177)Lu-, (131)I-, (124)I-, and (188)Re-Nanoobjects: Choice of the Best Radionuclide for Solid Tumour Treatment by Using TCP and NTCP Concepts.. In: Computational and Mathematical Methods in Medicine, Vol. 2015, p. 284360 [1-15] (2015). doi:10.1155/2015/284360.
2015
Kahloune, Merouane ; Lambert, Michel ; Hanin, François-Xavier ; Coche, Emmanuel ; Ghaye, Benoît. Multiple Splenic Infarctions Complicating Granulomatosis with Polyangiitis. In: JBR-BTR (Journal of the Belgian Society of Radiology), Vol. 98, no.3, p. 129 (2015). doi:10.5334/jbr-btr.798.
2015
Aubert, Léo ; Guilbert, Matthieu ; Corbet, Cyril ; Génot, Elisabeth ; Adriaenssens, Eric ; Chassat, Thierry ; Bertucci, François ; Daubon, Thomas ; Magné, Nicolas ; Le Bourhis, Xuefen ; Toillon, Robert-Alain. NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib.. In: OncoTarget, Vol. 6, no. 12, p. 9807-19 (2015).
2015
Danhier, Fabienne ; Danhier, Pierre ; De Saedeleer, Christophe ; Fruytier, Anne-Catherine ; Schleich, Nathalie ; des Rieux, Anne ; Sonveaux, Pierre ; Gallez, Bernard ; Préat, Véronique. Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors. In: International Journal of Pharmaceutics, Vol. 479, no. 2, p. 399-407 (2015). doi:10.1016/j.ijpharm.2015.01.009.
2015
Radi, Smaail ; Tighadouini, Said ; Feron, Olivier ; Riant, Olivier ; Bouakka, Mohammed ; Benabbes, Redouane ; Mabkhot, Yahia N. Synthesis of Novel β-Keto-Enol Derivatives Tethered Pyrazole, Pyridine and Furan as New Potential Antifungal and Anti-Breast Cancer Agents.. In: Molecules : a journal of synthetic organic and natural product chemistry, Vol. 20, no.11, p. 20186-20194 (2015). doi:10.3390/molecules201119684.
2015
Neveu, Marie-Aline ; Bol, Vanesa ; Bol, Anne ; Bouzin, Caroline ; Grégoire, Vincent ; Feron, Olivier ; Jordan, Bénédicte ; Gallez, Bernard. The increase in tumor oxygenation under carbogen breathing induces a decrease in the uptake of [(18)F]-fluoro-deoxy-glucose. In: Radiotherapy & Oncology, Vol. 116, no. 3, p. 400–403 (2015). doi:10.1016/j.radonc.2015.04.023.
2015
Burnet, Guillaume ; Lambert, Michel ; Annet, Laurence ; Lefebvre, Chantal. Unilateral adrenal hemorrhagic infarction in essential thrombocythemia. In: Acta Clinica Belgica, Vol. 70, no.6, p. 461-462 (2015). doi:10.1179/2295333715Y.0000000038.
2015
Vanhoutte, Laetitia ; Gallez, Bernard ; Feron, Olivier ; Balligand, Jean-Luc ; Esfahani, Hrag ; D'Hoore, William ; Moniotte, Stéphane. Variability of Mouse Left Ventricular Function Assessment by 11.7 Tesla MRI.. In: Journal of Cardiovascular Translational Research, Vol. 8, no. 6, p. 362-371 (2015). doi:10.1007/s12265-015-9638-0.
2014
Karmani, Linda ; Bouchat, Virginie ; Bouzin, Caroline ; Levêque, Philippe ; Labar, Daniel ; Bol, Anne ; Deumer, Gladys ; Marega, Riccardo ; Bonifazi, Davide ; Haufroid, Vincent ; Michiels, Carine ; Grégoire, Vincent ; Feron, Olivier ; Lucas, Stéphane ; Vander Borght, Thierry ; Gallez, Bernard. (89)Zr-labelled anti-endoglin antibody-targeted gold nanoparticles for imaging cancer: implications for future cancer therapy.. In: Nanomedicine, Vol. 9, no. 13, p. 1923-1937 (2014). doi:10.2217/nnm.13.185.
2014
Boidot, Romain ; Branders, Samuel ; Helleputte, Thibault ; Illan Rubio, Laila ; Dupont, Pierre ; Feron, Olivier. A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.. In: OncoTarget, Vol. 5, no.16, p. 6947-63 (2014).
2014
Porporato, Paolo ; Payen, Valéry ; Perez Escuredo, Jhudit ; De Saedeleer, Christophe ; Danhier, Pierre ; Copetti, Tamara ; Dhup, Suveera ; Tardy, Morgane ; Vazeille, Thibaut ; Bouzin, Caroline ; Feron, Olivier ; Michiels, Carine ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. In: Cell Reports, Vol. 8, p. 754-766 (2014). doi:10.1016/j.celrep.2014.06.043.
2014
Timmermans, Aurélie ; Balteau, Magali ; Gélinas, Roselle ; Renguet, Edith ; Ginion, Audrey ; de Meester, Carole ; Sakamoto, Kei ; Balligand, Jean-Luc ; Bontemps, Françoise ; Vanoverschelde, Jean-Louis ; Horman, Sandrine ; Beauloye, Christophe ; Bertrand, Luc. A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake.. In: American journal of physiology. Heart and circulatory physiology, Vol. 306, no. 12, p. 1619-1630 (2014). doi:10.1152/ajpheart.00965.2013.
2014
Balteau, Magali ; Van Steenbergen, Anne ; Timmermans, Aurélie ; Dessy, Chantal ; Behets-Wydemans, Gaëtane ; Tajeddine, Nicolas ; Castanares Zapatero, Diego ; Gilon, Patrick ; Vanoverschelde, Jean-Louis ; Horman, Sandrine ; Hue, Louis ; Bertrand, Luc ; Beauloye, Christophe. AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes.. In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 307, no. 8, p. H1120-1133 (2014). doi:10.1152/ajpheart.00210.2014.
2014
Draoui, Nihed ; Schicke, Olivier ; Seront, Emmanuel ; Bouzin, Caroline ; Sonveaux, Pierre ; Riant, Olivier ; Feron, Olivier. Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux.. In: Molecular Cancer Therapeutics, Vol. 13, no. 6, p. 1410-1418 (2014). doi:10.1158/1535-7163.MCT-13-0653.
2014
Fruytier, Anne-Catherine ; Magat, Julie ; Neveu, Marie-Aline ; Karroum, Oussama ; Bouzin, Caroline ; Feron, Olivier ; Jordan, Bénédicte ; Cron, Greg O ; Gallez, Bernard. Dynamic contrast-enhanced MRI in mouse tumors at 11.7 T: comparison of three contrast agents with different molecular weights to assess the early effects of combretastatin A4. In: NMR in Biomedicine, Vol. 27, no. 11, p. 1403-1412 (2014). doi:10.1002/nbm.3220.
2014
Sonveaux, Pierre. Découverte d'une stratégie capable d'empêcher la dissémination des métastases cancéreuses. In: Louvain médical, Vol. 133, no.9, p. 639-645 (30/11/2014).
2014
Leite-Moreira, Adelino F. ; Lourenço, André P. ; Balligand, Jean-Luc ; Bauersachs, Johann ; Clerk, Angela ; De Windt, Leon J. ; Heymans, Stephane ; Hilfiker-Kleiner, Denise ; Hirsch, Emilio ; Iaccarino, Guido ; Kaminski, Karol A. ; Knöll, Ralph ; Mayr, Manuel ; Tarone, Guido ; Thum, Thomas ; Tocchetti, Carlo G.. ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models. In: European Journal of Heart Failure, Vol. 16, no. 5, p. 509-518 (2014). doi:10.1002/ejhf.66.
2014
Belge, Catharina ; Hammond, Joanna ; Dubois, Emilie ; Manoury, Boris ; Hamelet, Julien ; Beauloye, Christophe ; Markl, Andreas ; Pouleur, Anne-Catherine ; Bertrand, Luc ; Esfahani, Hrag ; Jnaoui, Karima ; Götz, Konrad R ; Nikolaev, Viacheslav O ; Vanderper, Annelies ; Herijgers, Paul ; Lobysheva, Irina ; Iaccarino, Guido ; Hilfiker-Kleiner, Denise ; Tavernier, Geneviève ; Langin, Dominique ; Dessy, Chantal ; Balligand, Jean-Luc. Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase. In: Circulation, Vol. 129, no. 4, p. 451-462 (2014). doi:10.1161/CIRCULATIONAHA.113.004940.
2014
Hupin, Cloé ; Bouzin, Caroline ; Gohy, Sophie ; Polette, Myriam ; Lecocq, Marylène ; Pilette, Charles. Features of mesenchymal transition in the airway epithelium from chronic rhinosinusitis. In: Allergy, Vol. 69, no. 11, p. 1540-1549 (2014). doi:10.1111/all.12503.
2014
Montiel, Virginie ; Leon Gomez, Elvira ; Bouzin, Caroline ; Esfahani, Hrag ; Romero Perez, Miguel ; Lobysheva, Irina ; Devuyst, Olivier ; Dessy, Chantal ; Balligand, Jean-Luc. Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation.. In: Pflugers Archiv : European journal of physiology, Vol. 466, no. 2, p. 237-251 (2014). doi:10.1007/s00424-013-1325-x.
2014
Vanacker, Julie ; Aiswarya Viswanath, . ; De Berdt, Pauline ; Everard, Amandine ; Cani, Patrice D. ; Bouzin, Caroline ; Feron, Olivier ; Diogenes, Anibal ; Leprince, Julian ; des Rieux, Anne. Hypoxia modulates the differentiation potential of stem cells of the apical papilla (SCAP). In: The Journal of Endodontics, Vol. 40, no. 9, p. 1410–1418 (2014). doi:10.1016/j.joen.2014.04.008.
2014
Hermida Blanco, Nerea ; Balligand, Jean-Luc. Low-density lipoprotein-cholesterol-induced endothelial dysfunction and oxidative stress: the role of statins. In: Antioxidants & Redox Signaling, Vol. 20, no. 8, p. 1216-1237 (2014). doi:10.1089/ars.2013.5537.
2014
Unsöld, Bernhard ; Kaul, Axel ; Sbroggiò, Mauro ; Schubert, Carola ; Regitz-Zagrosek, Vera ; Brancaccio, Mara ; Damilano, Federico ; Hirsch, Emilio ; Van Bilsen, Marc ; Munts, Chantal ; Sipido, Karin ; Bito, Virginie ; Detre, Elke ; Wagner, Nana Maria ; Schäfer, Katrin ; Seidler, Tim ; Vogt, Johannes ; Neef, Stefan ; Bleckmann, Annalen ; Maier, Lars S ; Balligand, Jean-Luc ; Bouzin, Caroline ; Ventura-Clapier, Renée ; Garnier, Anne ; Eschenhagen, Thomas ; El-Armouche, Ali ; Knöll, Ralph ; Tarone, Guido ; Hasenfuß, Gerd. Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction. In: Cardiovascular Research, Vol. 101, no. 1, p. 97-107 (2014). doi:10.1093/cvr/cvt235.
2014
Louis, Caroline ; C.Dirtu, Alin ; Stas, Marie ; Guiot, Yves ; Malarvannan, Govindan ; Das, Krishna ; P.Costa, Daniel ; E.Crocker, Daniel ; Covaci, Adrien ; Debier, Cathy. Mobilisation of lipophilic pollutants from blubber in northern elephant seal pups (Mirounga angustirostris) during the post-weaning fast. In: Environmental Research, Vol. 132, p. 438-448 (2014). doi:10.1016/j.envres.2014.04.016.
2014
Danhier, Pierre ; De Preter, Géraldine ; Magat, Julie ; Godechal, Quentin ; Porporato, Paolo ; Jordan, Bénédicte ; Feron, Olivier ; Sonveaux, Pierre ; Gallez, Bernard. Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.. In: Contrast Media & Molecular Imaging, Vol. 9, no. 2, p. 143-153 (2014). doi:10.1002/cmmi.1553.
2014
Chereddy, Kiran Kumar ; Her, Charles-henry ; Comune, Michela ; Moia, Claudia ; Lopes, Alessandra ; Porporato, Paolo ; Vanacker, Julie ; Lam, Martin C ; Steinstraesser, Lars ; Sonveaux, Pierre ; Zhu, Huijun ; Ferreira, Lino S ; Vandermeulen, Gaëlle ; Préat, Véronique. PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.. In: Journal of Controlled Release, Vol. 194, no. C, p. 138-147 (2014). doi:10.1016/j.jconrel.2014.08.016.
2014
Porporato, Paolo ; Sonveaux, Pierre. Paving the way for a therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide. In: Molecular & Cellular Oncology, Vol. 2, no. 3, p. e968043 (2014). doi:10.4161/23723548.2014.968043.
2014
Spugnini, Enrico ; Sonveaux, Pierre ; Stock, Christian ; Perez-Sayans, Mario ; De Milito, Angelo ; Avnet, Sofia ; Garcia Garcia, Abel ; Harguidey, Salvador ; Fais, Stefano. Proton channels and exchangers in cancer. In: BBA - Biomembranes, Vol. 1848, no. 10 Pt B, p. 2715-2726. doi:10.1016/j.bbamem.2014.10.015.
2014
Noppe, Gauthier ; Dufeys, Cécile ; Buchlin, Patricia ; Marquet, Nicolas ; Castanares Zapatero, Diego ; Balteau, Magali ; Hermida Blanco, Nerea ; Bouzin, Caroline ; Esfahani, Hrag ; Viollet, Benoit ; Bertrand, Luc ; Balligand, Jean-Luc ; Vanoverschelde, Jean-Louis ; Beauloye, Christophe ; Horman, Sandrine. Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1.. In: Journal of molecular and cellular cardiology, Vol. 74C, no.74C, p. 32-43 (2014). doi:10.1016/j.yjmcc.2014.04.018.
2014
Martinsen, A ; Dessy, Chantal ; Morel, N. Regulation of calcium channels in smooth muscle: New insights into the role of myosin light chain kinase.. In: Channels (Austin), Vol. 8, no.5, p. 402-413 (2014). doi:10.4161/19336950.2014.950537.
2014
Bol, Vanesa ; Bol, Anne ; Bouzin, Caroline ; Labar, Daniel ; Lee, John Aldo ; Janssens, Guillaume ; Porporato, Paolo ; Sonveaux, Pierre ; Feron, Olivier ; Grégoire, Vincent. Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.. In: Acta Oncologica, Vol. 54, no. 2, p. 266-274 (2015). doi:10.3109/0284186X.2014.932006.
2014
de Meester, Carole ; Timmermans, Aurélie ; Balteau, Magali ; Ginion, Audrey ; Roelants, Véronique ; Noppe, Gauthier ; Porporato, Paolo ; Sonveaux, Pierre ; Viollet, Benoît ; Sakamoto, Kei ; Feron, Olivier ; Horman, Sandrine ; Vanoverschelde, Jean-Louis ; Beauloye, Christophe ; Bertrand, Luc. Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.. In: Cardiovascular Research, Vol. 101, no. 1, p. 20-29 (2014). doi:10.1093/cvr/cvt227.
2014
De Miranda Capeloa, Tania Isabel ; Caramelo, Francisco ; Fontes-Ribeiro, Carlos ; Gomes, Célia ; Silva, Ana P. Role of methamphetamine on glioblastoma cytotoxicity induced by doxorubicin and methotrexate.. In: Neurotoxicity research, Vol. 26, no.3, p. 216-27 (2014). doi:10.1007/s12640-014-9464-1.
2014
Steinstraesser, Lars ; Lam, Martin C ; Jacobsen, Frank ; Porporato, Paolo ; Chereddy, Kiran Kumar ; Becerikli, Mustafa ; Stricker, Ingo ; Hancock, Robert Ew ; Lehnhardt, Marcus ; Sonveaux, Pierre ; Préat, Véronique ; Vandermeulen, Gaëlle. Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing.. In: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, no. 4, p. 734-742 (2014). doi:10.1038/mt.2013.258.
2014
Pothen, Lucie ; Rouvière, Héloïse ; Poncin, Renaud ; Michaux, Lucienne ; Damoiseau, Philippe ; Lambert, Michel. Systemic capillary leak syndrome revealing a diffuse large B-cell lymphoma.. In: Acta Clinica Belgica, Vol. 69, no. 4, p. 305-308 (2014). doi:10.1179/0001551214Z.00000000076.
2014
Tarone, Guido ; Balligand, Jean-Luc ; Bauersachs, Johann ; Clerk, Angela ; De Windt, Leon ; Heymans, Stephane ; Hilfiker-Kleiner, Denise ; Hirsch, Emilio ; Iaccarino, Guido ; Knöll, Ralph ; Leite-Moreira, Adelino F ; Lourenço, André P ; Mayr, Manuel ; Thum, Thomas ; Tocchetti, Carlo G. Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.. In: European journal of heart failure, Vol. 16, no.5, p. 494-508 (2014). doi:10.1002/ejhf.62 (Accepté/Sous presse).
2014
Corbet, Cyril ; Draoui, Nihed ; Polet, Florence ; Pinto Fernandez, Adan ; Drozak, Xavier ; Riant, Olivier ; Feron, Olivier. The SIRT1/HIF2α Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy.. In: Cancer Research, (2014). doi:10.1158/0008-5472.CAN-14-0705.
2014
Rainero, Elena ; Cianflone, Cristina ; Porporato, Paolo ; Chianale, Federica ; Malacarne, Valeria ; Bettio, Valentina ; Ruffo, Elisa ; Ferrara, Michele ; Benecchia, Fabio ; Capello, Daniela ; Paster, Wolfgang ; Locatelli, Irene ; Bertoni, Alessandra ; Filigheddu, Nicoletta ; Sinigaglia, Fabiola ; Norman, Jim C ; Baldanzi, Gianluca ; Graziani, Andrea. The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.. In: PLoS One, Vol. 9, no. 6, p. e97144 (2014). doi:10.1371/journal.pone.0097144.
2014
Rombouts, Charlotte ; Aerts, An ; Quintens, Roel ; Baselet, Bjorn ; El Saghire, Houssein ; Harms-Ringdahl, Mats ; Haghdoost, Siamak ; Janssen, Ann ; Yentrapalli, Ramesh ; Benotmane, Mohammed Abderrafi ; Van Oostveldt, Patrick ; Baatout, Sarah. Transcriptomic profiling suggests a role for IGFBP5 in premature senescence of endothelial cells after chronic low dose rate irradiation. In: International Journal of Radiation Biology, Vol. 90, no. 7, p. 560-574 (2014). doi:10.3109/09553002.2014.905724.
2014
Götz, Konrad ; Sprenger, Julia ; Perera, Ruwan K ; Steinbrecher, Julia H ; Lehnart, Stephan E ; Kuhn, Michaela ; Gorelik, Julia ; Balligand, Jean-Luc ; Nikolaev, Viacheslav O. Transgenic Mice for Real Time Visualization of cGMP in Intact Adult Cardiomyocytes.. In: Circulation research, (2014). doi:10.1161/CIRCRESAHA.114.302437.
2014
des Rieux, Anne ; De Berdt, Pauline ; Ansorena Artieda, Eduardo ; Ucakar, Bernard ; Jacobs, Damien ; Schakman, Olivier ; Audouard, Emilie ; Bouzin, Caroline ; Auhl, Dietmar ; Simón-Yarza, Teresa ; Feron, Olivier ; Blanco-Prieto, Maria J ; Carmeliet, Peter ; Bailly, Christian ; Clotman, Frédéric ; Préat, Véronique. Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord. In: Journal of Biomedical Materials Research. Part A, Vol. 102, no. 7, p. 2345–2355 (2014). doi:10.1002/jbm.a.34915.
2014
Danhier, Fabienne ; Touan, Bi Kouhé Trésor ; Duhem, Nicolas ; Ucakar, Bernard ; Staub, Aurélie ; Draoui, Nihed ; Feron, Olivier ; Préat, Véronique. Vitamin E-based micelles enhance the anticancer activity of doxorubicin.. In: International Journal of Pharmaceutics, Vol. 476, no. 1-2, p. 9-15 (2014). doi:10.1016/j.ijpharm.2014.09.028.
2018
Baselet, Bjorn ; Ramadan, R ; Benotman, AM ; Sonveaux, Pierre ; Baatout, Sarah ; Aerts, An. Selected endothelial responses after ionizing radiation exposure. In: Endothelial dysfunction - old concepts and new challenges, Intech: Rijeka (Croatia), 2018, p. 365-390. 978-953-51-5698-7. doi:10.5772/intechopen.72386.
2018
Mailleux, Florence ; Beauloye, Christophe ; Balligand, Jean-Luc ; Horman, Sandrine ; Bertrand, Luc. Studying the Role of AMPK in Cardiac Hypertrophy and Protein Synthesis.. In: AMPK: Methods and Protocols, Humana Press, Inc.: New York, 2018. 978-1-4939-7597-6. doi:10.1007/978-1-4939-7598-3_21.
2022
Sonveaux, Pierre. Metastasis prevention (in breast cancer) with superoxide scavengers. Eadiotherapy Online-Seminar Series of the University of Maastricht/MUMC/Maastro (Maastricht, The Netherlands, 11/03/2022).
2022
Grasso, Debora ; Sonveaux, Pierre. Preservation of mitochondrial integrity participates in radioresistance in head and neck mouse cancer models. ESTRO 2022 (Copenhaguen, Denmark, du 06/05/2022 au 10/05/2022).
2022
Sonveaux, Pierre. Towards the prevention of local recurrence and distant metastases in breast cancer. Meeting Series of the Royal Society of Chemistry (RSC) - Belgian Section (Louvain-la-Neuve (online), 19/05/2022).
2021
Sonveaux, Pierre ; Frédérick, Raphaël. Identification and development of LDH inhibitors to treat cancer. Seminar Series of the European Institute of Chemistry and Biology (IECB) (11/06/2021).
2021
Sonveaux, Pierre. Lactate signals pseudohypoxia in cancer. EMBO workshop: lactate: unconventional roles of a nutrient along tumor landscape (Florence, Italy, du 21/06/2021 au 23/06/2021).
2021
Dumas, Laurent ; Metzinger, Thomas ; Marchand,Dorothée ; Esfahani, Hrag ; Kurbanova, S ; Maistriaux, Louis ; Bastien, Estelle ; Daskalopoulos, Evangelos-Panagiotis ; Horman, Sandrine ; Dessy, Chantal. MiR-199a is differentially regulated during physiological and pathological cardiac hypertrophy. HFA Winter Meeting 2021 (On line, du 20/01/2021 au 21/01/2021). In: European Journal of Heart Failure, Vol. 23, no.Suppl 1, p. 9 (2021). doi:10.1002/ejhf.2100.
2021
Sonveaux, Pierre. Mitochondrial superoxide at the core of the metastatic process of cancers. Journée Mitochondrie Métabolisme et Cancer (Angers University, France, 17/11/2021).
2021
Sonveaux, Pierre. Opening lecture: preventing cancer metastasis with superoxide scavengers. 9th International Symposium of Gunma University for Advanced Research: Breakthroughs in Cancer Metabolism and Technological Pers (Gunma, Japan, 25/02/2021).
2021
De Miranda Capeloa, Tania Isabel ; Paolo E Porporato ; Sonveaux, Pierre. Preventing cancer metastasis with specific inhibitors of mitochondrial superoxide. 33rd AICC Annual conference: International Meeting on Cancer Metabolism (Turin, Italy, du 22/11/2021 au 25/11/2021).
2021
Sonveaux, Pierre. Preventing cancer metastasis with superoxide scavengers. 4th Metabolism & Cancer conference (Bordeaux, France, du 27/05/2021 au 29/05/2021).
2021
Vanderputten, Marie ; Aboubakar Nana, Frank ; Bouzin, Caroline ; Hoton, Delphine ; Stanciu Pop, Claudia Maria ; Lecocq, Marylène ; Ambroise, Jérôme ; Pilette, Charles ; Ocak, Sebahat. Prognostic Significance of IgA+ B Cells in Non-Small Cell Lung Cancer [P72.10]. 2020 World Conference on Lung Cancer (Virtual, du 28/01/2021 au 31/01/2021). In: Journal of Thoracic Oncology, Vol. 16, no.3, p. S569 (2021). doi:10.1016/j.jtho.2021.01.1028.
2021
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Hubinont, Corinne ; Danhaive, Olivier ; Sonveaux, Pierre ; Debieve, Frédéric. Risk of COVID-19 maternofetal transmission at term: new evidence against placental infection by SARS-CoV-2. IFPA Annual Meeting 2021 (Virtual, du 30/08/2021 au 02/09/2021).
2021
Colson, Arthur ; Lambert, Isaline ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debieve, Frédéric. Use of the Hypoxia-Inducible Factor (HIF)-2α Inhibitor PT2385 in Placental Dysfunction: New Intervention Addressing Fetal Growth Restriction and Preeclampsia. 68th annual meeting of the Society for Reproductive Investigation (Boston, du 06/07/2021 au 09/07/2021).
2020
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Hypoxia-Inducible Factor 2α (HIF-2α) Impairs Placental Development in Fetal Growth Restriction (FGR). 22th annual meeting of the Society for Reproductive Investigation (Vancouver, du 10/03/2020 au 14/03/2020).
2020
Poncin, William ; Baudet, Lia ; Reychler, Gregory ; Duprez, Frédéric ; Liistro, Giuseppe ; Belkhir, Leïla ; Pothen, Lucie ; Yildiz, Halil ; Yombi, Jean Cyr ; De Greef, Julien. Impact of an improvised system on preserving oxygen supplies in patients with COVID-19. ERS International Congress 2020 (Virtual, du 07/09/2020 au 09/09/2020).
2020
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; Porporato, PE ; Sonveaux, Pierre. Targeting mitochondrial reactive oxygen species (mtROS) inbreast cancer: a way to blunt cell migration without affecting the cytotoxic effects of standard therapies. BACR Annual Meeting (Brussels, Belgium, 07/02/2020).
2019
Darius, Tom ; Vergauwen, Martial ; Smith, TB ; Patel, K ; Aydin, Selda ; Joris, Virginie ; Buemi, Antoine ; De Meyer, Martine ; Nath, J ; Dessy, Chantal ; Ludwig, C ; Gianello, Pierre ; Mourad, Michel. Brief initial O2 supply during continuous hypothermic machine perfusion might be the most efficient strategy to drive the metabolic switch to aerobic metabolism and subsequently to improve early renal graft function. 6th IREC Phd Day (Brussels, Belgium, 08/03/2019).
2019
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Debiève, Frédéric. Hypoxia-Inducible Factor 2 (EPAS1) Decreases Syncytialization in Primary Villous Cytotrophoblasts. 21th annual meeting of the Society for Reproductive Investigation (Paris, du 12/03/2019 au 16/03/2019).
2019
Vander Linden, Catherine. Metabolic plasticity and adaptive resistance to metabolic inhibitors in tumor cells. IREC PhD day 2019 (UCLouvain Woluwe, 08/03/2019).
2019
Vander Linden, Catherine. Metabolic plasticity and adaptive resistance to metabolic inhibitors in tumor cells. Televie's researchers annual seminar 2019 (Gembloux AgroTech (ULiège), 28/01/2019).
2019
Vander Linden, Catherine. Metabolic plasticity and adaptive resistance to metabolic inhibitors in tumor cells. Belgian Association for Cancer Research (BACR) annual meeting 2019 (Université d'Anvers, 01/02/2019).
2019
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Oxygen-resistant Hypoxia-Inducible Factor-2a (EPAS1) Mutant Inhibits Forskolin-induced Differentiation of Choriocarcinoma Cell Line BeWo. CTR Annual Conference (Cambridge, du 08/07/2019 au 09/07/2019).
2019
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; Porporato, PE ; Sonveaux, Pierre. Targeting mitochondrial reactive oxygen species (mtROS) impairs breast cancer cell migration without affecting the cytotoxic effects of standard therapies. 6th meeting of the International Society of Cancer Metabolism (ISCaM) (Braga, Portugal, du 17/10/2019 au 19/10/2019).
2019
De Miranda Capeloa, Tania Isabel ; Krzystyniak, Joanna ; Porporato, PE ; Sonveaux, Pierre. Targeting mitochondrial reactive oxygen species (mtROS) impairs breast cancer cell migration without affecting the cytotoxic effects of standard therapies. BACR Annual Meeting (Liege, Belgium, 01/02/2019).
2019
Dierge, Emeline. Therapeutic exploitation of tumor addiction to fatty acids under acidosis. IREC PhD Day (Woluwé-Saint-Lambert, 08/03/2019).
2018
Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. Toulouse Onco-week (Toulouse, France, du 05/02/2018 au 07/02/2018).
2018
Corbet, Cyril. Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and induce tumor radiosensitization. EACR meeting "Mechanisms to Therapies: Innovations in Cancer Metabolism" (Bilbao (Spain)).
2018
Corbet, Cyril. Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and induce tumor radiosensitization. ISCaM 5th Annual Meeting – Metabolic Adaptations and Targets in Cancer (Bratislava (Slovakia)).
2018
Corbet, Cyril. Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and induce tumor radiosensitization. 3rd International Workshop NO-CANCER 2018 (Novara (Italy)).
2018
Corbet, Cyril. Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and induce tumor radiosensitization. Metabolism in cancer and stromal cells (2nd edition) - VIB conferences (Leuven (Belgium)).
2018
Dierge, Emeline. Effets antitumoraux des acides gras polyinsaturés à longue chaine. Acides gras, pathologies chroniques et cancers (Louvain-la-Neuve, 23/10/2018).
2018
Corbet, Cyril. Interruption of lactate-based metabolic symbiosis by inhibiting mitochondrial pyruvate transport unravels tumor growth inhibitory and radiosensitizing effects. Keystone symposia "Tumor Metabolism" (Snowbird, Utah (USA)).
2018
Payen, Valéry ; Hsu, MY ; Radecke, KS ; Wyart, E ; Vazeille, Thibaut ; Bouzin, Caroline ; Porporato, Paolo E ; Sonveaux, Pierre. Monocarboxylate transporter 1 (MCT1) promotes tumor metastasis independently of its activity as a transporter of lactate. ISCaM2018 (Bratislava, Slovakia, du 17/10/2018 au 20/10/2018).
2017
DUISIT, Jérôme ; Maistriaux, Louis ; Taddeo, A ; Tsering, W ; Orlando, G ; Joris, Virginie ; Coche, Emmanuel ; Behets Wydemans, Catherine ; Lerut, Jan ; Dessy, Chantal ; Cossu, G ; Vögelin, E ; Rieben, R ; Gianello, Pierre ; Lengelé, Benoît. Bioengineering a human face graft: the matrix of identity. ISVCA annual meeting (Salzburg, du 26/10/2017 au 27/10/2017).
2017
DUISIT, Jérôme ; Maistriaux, Louis ; Orlando, G ; Joris, Virginie ; Dessy, Chantal ; Behets Wydemans, Catherine ; Gianello, Pierre ; Lengelé, Benoît. Bioengineering a human face graft: the matrix of identity. 6th triennial congress of the Advanced Digital Technology in Head and Neck reconstruction conferences (Amiens, du 31/05/2017 au 3/6/2017).
2017
Santiago de Jesus, Joao Pedro. Chronic acidosis reprograms tumor metabolism towards an exacerbated FAO pathway and glucose-independent FAS routes. Association Belge Pour L'étude du Cancer (Katholieke Universiteit Leuven, 28/01/2017).
2017
De Miranda Capeloa, Tania Isabel ; Giachino, C ; Corso, S ; Giordano, S. Gastric cancer stem cells: do they maintain the genetic alterations of driver genes identified in the primary tumor?. 2nd EACR-OECI conference: MAKING IT PERSONAL Cancer Precision Medicine (Amsterdam, The Netherlands, du 13/03/2017 au 16/03/2017).
2017
Apicella, M ; Migliore, C ; Menegon, S ; Cargnelutti, M ; De Miranda Capeloa, Tania Isabel ; Cassoni, P ; Sapino, A ; Bass, A ; Corso, S ; Giordano, S. Targeting HER2 in gastric cancer: Hints from a gastric PDX platform. EACR-AACR-SIC Special Conference 2017: The Challenges of Optimizing Immuno- and Targeted Therapies (Florence, Italy, du 24/06/2017 au 27/06/2017).
2017
Corbet, Cyril. Tumor acidosis rewires metabolic cancer cell preferences through mitochondrial protein acetylation. Keystone symposia "Tumor Metabolism: Mechanisms and Targets" (Whistler, British Columbia, Canada).
2016
Payen, Valéry ; Porporato, Paolo ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. 212th meeting of the Belgian Society of Biochemistry and Molecular Biology/Spring meeting of the FNRS contact group on oxidative processes and antioxidants (Louvain-la-Neuve, Belgium, 22/04/2016).
2016
Corbet, Cyril. Acidosis drives the reprogramming of both fatty acid oxidation and synthesis in cancer cells. Cell-VIB symposium: Hallmarks of cancer (Ghent (Belgium)).
2016
Santiago de Jesus, Joao Pedro. Chronic acidosis reprograms tumor metabolism towards an exacerbated FAO pathway and glucose-independent FAS routes. Ecole doctorale en Cancérologie Expérimentale (Université Catholique de Louvain, 08/12/2016).
2016
De Miranda Capeloa, Tania Isabel ; Apicella, M ; Migliore, C ; Sapino, A ; Cassoni, P ; Corso, S ; Giordano, S. Dual anti-MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort. VHIO SPECIAL SYMPOSIUM: Towards Predictive Cancer Models (Barcelona, Spain, 01/05/2016).
2016
De Miranda Capeloa, Tania Isabel ; Apicella, M ; Migliore, C ; Sapino, A ; Cassoni, P ; Corso, S ; Giordano, S. Dual anti-MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort. 58th annual meeting of the italian cancer society (Verona, Italy, du 05/09/2016 au 08/09/2016).
2016
Menegon, S ; Apicella, M ; Migliore, C ; De Miranda Capeloa, Tania Isabel ; Cargnelutti, M ; Degiuli, M ; Sapino, A ; Cassoni, P ; De Simone, M ; Comoglio, PM ; Marsoni, S ; Corso, S ; Gioardano, S. Gastric cancer in the age of targeted agents: identification and validation of novel therapeutic strategies through the generation of a patient-derived xenografts platform. AACR 107th Annual Meeting 2016 (New Orleans, LA, USA, du 16/04/2016 au 20/04/2016).
2016
Craps, Julie ; joris, virginie ; Hepp, Michael ; de ville de goyet, christine ; de Bournonville, Marc ; Many, Marie-Christine. Increase of NOX-4, VEGF and GLUT-1 in grave's disease. 39th annual meeting of the european thyroi association (Copenhagen).
2016
Payen, Valéry ; Radecke, Kristin ; Hsu, Myriam ; Bouzin, Caroline ; Porporato, Paolo ; Sonveaux, Pierre. MCT1 promotes cancer cell migration, invasion and metastasis. Annual meeting of the Belgian Association for Cancer Research (Brussels, 30/01/2016).
2016
Payen, Valéry ; Hsu, Myriam ; Radecke, Kristin ; Bouzin, Caroline ; Porporato, Paolo ; Sonveaux, Pierre. MCT1 targeting rewires tumor cell metabolism towards increased oxidative phosphorylation. 19th annual Forum of the Belgian Society of Pharmaceutical Sciences (Brussels, du 17/10/2016 au 18/10/2016).
2016
Corbet, Cyril. Metabolic reprogramming in response to chronic acidosis regulates tumor cell protein acetylation. ISCaM 3rd Annual Meeting – Metabolic networks in cancer (Brussels (Belgium)).
2016
Corbet, Cyril. Metabolic reprogramming in response to chronic acidosis regulates tumor cell protein acetylation. BACR Annual meeting (Brussels (Belgium)).
2016
joris, virginie ; Lobysheva, Irina ; Balligand, Jean-Luc ; Many, Marie-Christine ; Dessy, Chantal. Microrna 199-A3P inhibition induces and increase of the expression of deiodinase 2 in aortic endothelial cells. 39th annual meeting of thz european thyroid association (Copenhagen, du 03/09/2016 au 06/09/2016).
2016
Hsu, Myriam ; Payen, Valéry ; Radecke, Kristin ; Porporato, Paolo ; Sonveaux, Pierre. Monocarboxylate transporter 1 promotes tumor metastasis independently of its transporter activity. 19th annual Forum of the Belgian Society of Pharmaceutical Sciences (Brussels, du 17/10/2016 au 18/10/2016).
2016
Sonveaux, Pierre. Oncometabolite lactate promotes tumor growth. ICTR-PHE (Genève, Suisse, du 15/02/2016 au 19/02/2016).
2016
Migliore C ; Apicella M ; Menegon S ; Cargnelutti, M ; De Miranda Capeloa, Tania Isabel ; Cassoni, P ; Sapino A ; Bass, A ; Corso, S ; Giordano, S. Precision medicine in gastric cancer: identification of negative response predictors for trastuzumab therapy. Europdx Workshop 2016: PDX models in clinical oncology and cancer precision medicine (Weggis, Switzerland, du 03/10/2016 au 05/10/2016).
2016
Many, Marie-Christine ; joris, virginie ; Marique, Lancelot ; Craps, Julie. oxidative stress in skin adipocytes from grave's patients. 39th annual meeting of the european association (Copenhagen, du 03/09/2016 au 06/09/2016).
2015
Catry, Emilie ; Pachikian, Barbara D. ; Neyrinck, Audrey M. ; Bouzin, Caroline ; Cani, Patrice D. ; Dessy, Chantal ; Delzenne, Nathalie M.. 0396 : Prebiotics supplementation improves the endothelial dysfunction induced by a nutritional deficiency in n-3 polyunsaturated fatty acids (PUFA). Printemps de la Cardiologie : Recherche Fondamentale et Clinique (Centre de Congrès Pierre Baudis, Toulouse, France, du 02/04/2015 au 03/04/2015). In: Archives of Cardiovascular Diseases. Supplements, Vol. 7, no.2, p. 137 (avril 2015). doi:10.1016/S1878-6480(15)30018-5.
2015
Porporato, Paolo ; Payen, Valéry ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. Keystone Symposium: integrating metabolism and tumor biology (Vancouver, BC, Canada, du 13/01/2015 au 18/01/2015).
2015
Payen, Valéry ; Porporato, Paolo ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. 7th meeting of the International Cancer Microenvironment Society (Tel-Aviv, Israël, du 11/10/2015 au 15/10/2015).
2015
Sonveaux, Pierre. LDHB controls autophagy in cancer. Abcam Cancer and Metabolism meeting (Cambridge, UK, du 28/09/2015 au 30/09/2015).
2015
Payen, Valéry ; Radecke, Kristin ; Porporato, Paolo ; Sonveaux, Pierre. MCT1 promotes cancer cell migration, invasion and metastasis. 2nd annual meeting of the International Society of Cancer Metabolism (Venice, Italy, du 16/09/2015 au 19/09/2015).
2015
Payen, Valéry ; Radecke, Kristin ; Porporato, Paolo ; Sonveaux, Pierre. MCT1 promotes cancer cell migration, invasion and metastasis.. FEBS advanced lecture course on molecular mechanisms of signal transduction and cancer (Spetses, Greece, du 16/08/2015 au 24/08/2015).
2015
Corbet, Cyril ; Draoui, Nihed ; Polet, Florence ; Pinto Fernandez, Adan ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: a shift towards reductive glutamine metabolism driven by the SIRT1/HIF2alpha axis. BACR (Belgian Association for Cancer Research) Annual Meeting (Université Catholique de Louvain - Brussels, 31/01/2015).
2015
Corbet, Cyril ; Draoui, Nihed ; Polet, Florence ; Pinto Fernandez, Adan ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: a shift towards reductive glutamine metabolism driven by the SIRT1/HIF2alpha axis . Keystone Symposium "Integrating Metabolism and Tumor Biology" (Vancouver, British Columbia, du 13/01/2015 au 18/01/2015).
2015
Draoui, Nihed ; Polet, Florence ; Pinto, Adan ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: a shift towards reductive glutamine metabolism driven by the SIRT1/HIF2alpha axis. Annual meeting of Belgian Association for Cancer Research - Tumor metabolism and mitochondria (Université Catholique de Louvain - Brussels, 31/01/2015).
2015
Draoui, Nihed ; Polet, Florence ; Pinto, Adan ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: a shift towards reductive glutamine metabolism driven by the SIRT1/HIF2 axis . Keystone Symposium "Integrating Metabolism and Tumor Biology" (Vancouver, British Columbia, du 13/01/2015 au 18/01/2015).
2015
Corbet, Cyril. Metabolic reprogramming in response to chronic acidosis regulates tumor cell protein acetylation. 2nd Annual meeting of the ISCAM (International Society of Cancer Metabolism) (Venice, Italy, du 16/09/2015 au 19/09/2015).
2015
Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive. Seminar Series of the Department of Cell Biology Sciences, Geneva University (Geneva, Switzerland).
2015
Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive. Minisymposium on Cancer Cell Metabolism, Karolinska Institutet, Stockholm (Stockholm, Sweden, du 04/11/2015 au 06/11/2015).
2015
Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive. XF’s user group meeting (Amsterdam, The Netherlands, du 02/06/2015 au 04/06/2015).
2015
Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive. Annual Meeting of the Belgian Society of Pharmaceutical Sciences (BSPS) (Blankenberge, du 28/05/2015 au 29/05/2015).
2015
Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive. Seminar Series of the Department of Radiation Oncology, Maastro Clinics (Maastricht, The Netherlands, 09/07/2015).
2015
Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive.. Nobel Forum: frontiers in cancer research and therapy (Karolinska Institutet, Stockholm, Sweden, du 05/03/2015 au 06/03/2015).
2015
Porporato, Paolo ; Payen, Valéry ; Sonveaux, Pierre. Mitochondrial metabolism promotes metastatic progression. . EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: From Cancer Biology to the Clinic (Florence (IT), du 20/06/2015 au 23/06/2015).
2015
Payen, Valéry ; Brisson, Lucie ; Porporato, Paolo ; Sonveaux, Pierre. Monocarboxylate transporter 1 (MCT1) promotes oxidative tumor cell migration. BACR annual meeting (Brussels, Belgium, 31/01/2015).
2015
Sonveaux, Pierre ; Machiels, Jean-Pascal. New tracks in cancer research. Council of the Louvain Foundation (Louvain-la-Neuve, Belgium, 27/11/2015).
2015
Catry, Emilie ; Pachikian, Barbara D. ; Neyrinck, Audrey M. ; Bouzin, Caroline ; Cani, Patrice D. ; Dessy, Chantal ; Delzenne, Nathalie M.. O44: La supplémentation en prébiotiques améliore la dysfonction endothéliale induite par une déficience nutritionnelle en acides gras polyinsaturés de type n–3. Congrès annuel de la SFD et de la SFD Paramédical (Bordeaux, France, du 24/03/2015 au 27/03/2015). In: Diabetes & Metabolism, Vol. 41, no.suppl 1, p. A12-A13 (march 2015). doi:10.1016/S1262-3636(15)30044-6.
2015
Catry, Emilie ; Neyrinck, Audrey M. ; Bouzin, Caroline ; Pachikian, Barbara D. ; Lobysheva, Irina ; Cani, Patrice D. ; Dessy, Chantal ; Delzenne, Nathalie M.. OR029 : Prebiotics Supplementation Improves the Endothelial Dysfunction Induced by a Nutritional Depletion in N-3 Polyunsaturated Fatty Acids. ESPEN congress 2015 (Lisbon, Portugal, du 05/09/2015 au 08/09/2015). In: Clinical Nutrition ESPEN, Vol. 34, no.suppl 1, p. S12 (september 2015). doi:10.1016/S0261-5614(15)30129-1.
2015
Sonveaux, Pierre. Oncometabolite lactate promotes tumor growth. 10th International Carbonic Anhydrase Meeting (Maastricht, The Netherlands, du 20/05/2015 au 22/06/2015).
2015
Sonveaux, Pierre. Proton export by glycolytic cancer cells. Annual meeting of the ISCaM (Venice, Italy, du 16/09/2015 au 20/09/2015).
2015
Pinto Fernandez, Adan ; Draoui, Nihed ; Corbet, Cyril ; Polet, Florence ; Riant, Olivier ; Feron, Olivier. Small molecule inhibitor of deubiquitinating enzymes exerts potent anticancer effects through ER stress exacerbation. BACR (Belgian Association for Cancer Research) Annual Meeting (Université Catholique de Louvain Avenue E. Mounier 51 - Auditoire G , 31/01/2015).
2015
Sonveaux, Pierre. Tumor progression under metabolic control: cooperation, angiogenesis & metastasis. Seminar Series of the William Harvey Research Institute, Queen Mary University of London (London, 23/02/2015).
2014
Sonveaux, Pierre. A metabolic switch promotes mtROS-dependent tumor metastasis. Contact group on oxidative stress and antioxidants & 210th meeting of the Belgian Society for Biochemistry & Molecular Biology (Liège, Belgium, 25/04/2014).
2014
Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. Seminars Series of the Ludwig Boltzmann Institute for Cancer Research (Vienna, Austria, 04/07/2014).
2014
Porporato, Paolo ; Payen, Valéry ; Perez Escuredo, Jhudit ; De Saedeleer, Christophe ; Danhier, Pierre ; Feron, Olivier ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. BACR annual meeting (Ghent, Belgium, 01/02/2014).
2014
Porporato, Paolo ; Payen, Valéry ; Perez Escuredo, Jhudit ; De Saedeleer, Christophe ; Danhier, Pierre ; Feron, Olivier ; Gallez, Bernard ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. 15th International Biennial Congress of the Metastasis Research (MRS) Society (Heidelberg, Germany, du 28/06/2014 au 01/07/2014).
2014
Porporato, Paolo ; Payen, Valéry ; Perez Escuredo, Jhudit ; De Saedeleer, Christophe ; Danhier, Pierre ; Copetti, Tamara ; Dhup, Suveera ; Tardy, Morgane ; Vazeille, Thibaut ; Bouzin, Caroline ; Feron, Olivier ; Michiels , Carine ; Gallez, Bernard ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. Cell Symposia: stem cell energetics (Berkeley, California, USA, du 09/12/2014 au 11/12/2014).
2014
Porporato, Paolo ; Payen, Valéry ; Perez Escuredo, Jhudit ; De Saedeleer, Christophe ; Danhier, Pierre ; Feron, Olivier ; Gallez, Bernard ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. Annual meeting of the American Association for Cancer Research (AACR) (San Diego, California, USA, du 05/04/2014 au 09/04/2014).
2014
Payen, Valéry ; Porporato, Paolo ; Perez Escuredo, Jhudit ; De Saedeleer, Christophe ; Danhier, Pierre ; Copetti, Tamara ; Dhup, Suveera ; Tardy, Morgane ; Vazeille, Thibaut ; Bouzin, Caroline ; Feron, Olivier ; Michiels, Carine ; Gallez, Bernard ; Sonveaux, Pierre. A mitochondrial switch promotes tumor metastasis. Autumn meeting of the Belgian Society of Physiology and Pharmacology (BSPP) (Brussels, Belgium, 17/10/2014).
2014
Bony, Emilie ; Macé , Yohan ; Delvaux, David ; Pinto Fernandez, Adan ; Mathieu, Véronique ; Kiss , Robert ; Feron, Olivier ; Riant , Olivier ; Quetin-Leclercq, Joëlle. A new series of combretastatin analogues: LC-HRMS metabolite identification. Drug Analysis 2014 ((Belgium) Liege, du 22/06/2014 au 25/06/2014).
2014
Vanhoutte, Laetitia ; Esfahani, Hrag ; Feron, Olivier ; Balligand, Jean-Luc ; Gallez, Bernard ; Moniotte, Stéphane. Assessment of the accuracy and reproducibility of left ventricular mass and volumes measurements in mice using an 11.7T MRI machine. Frontiers in CardioVascular Biology 2014 ((Spain) Barcelona, du 04/06/2014 au 06/06/2014). In: Cardiovascular Research, Vol. 103, no.Suppl 1, p. S143 (2014). doi:10.1093/cvr/cvu098.
2014
Sonveaux, Pierre. Characterization and therapeutic targeting of lactate shuttles in cancer. Seminar Series of the Institute of Orthopedics, Rizzoli Institute (Bologna, Italy, 04/11/2014).
2014
Payen, Valéry ; De Saedeleer, Christophe ; Porporato, Paolo ; Copetti, Tamara ; Perez Escuredo, Jhudit ; Brisson, Lucie ; Feron, Olivier ; Sonveaux, Pierre. Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration. BACR annual meeting (Ghent,, 01/02/2014).
2014
Payen, Valéry ; De Saedeleer, Christophe ; Porporato, Paolo ; Copetti, Tamara ; Perez Escuredo, Jhudit ; Brisson, Lucie ; Feron, Olivier ; Sonveaux, Pierre. Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration. 11th meeting of the FRS-FNRS Contact group on oxidative stress and antioxidants & 210th meeting of the Belgian Society for Biochemistry & Molecular Biology (Liège, Belgium, 25/04/2014).
2014
Payen, Valéry ; De Saedeleer, Christophe ; Porporato, Paolo ; Copetti, Tamara ; Perez Escuredo, Jhudit ; Brisson, Lucie ; Feron, Olivier ; Sonveaux, Pierre. Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration. Cell Symposia: stem cell energetics (Berkeley, California, USA, du 09/12/2014 au 11/12/2014).
2014
Gallina, C ; Accomasso L ; De Miranda Capeloa, Tania Isabel ; Saviozzi; S ; Turinetto, V ; Penna, C ; Tullio, F ; Catalano, F ; Alberto, G ; Alloatti, G ; Pagliaro, P ; Giachino, G. Human mesenchymal stem cells labeled with fluorescent silica nanoparticles appear to have a differential migratory behavior in an ex vivo rat model of myocardial infarction. II Meeting of the Department of Clinical and Biological Sciences (Turin, Italy, 16/09/2014).
2014
Sonveaux, Pierre. Identification of a mitochondrial switch that promotes tumor metastasis. Métabolisme de la cellule tumorale et ses cibles thérapeutiques (Caen, France, du 07/11/2014 au 09/11/2014).
2014
Brisson, Lucie ; Copetti, Tamara ; Sboarina, Martina ; Dethier, Coralie ; Sonveaux, Pierre. LDHB regulates autophagy-dependent tumor cell proliferation. Physiology (London, du 30/06/2014 au 02/07/2014).
2014
Brisson, Lucie ; Copetti, Tamara ; Sboarina, Martina ; Dethier, Coralie ; Sonveaux, Pierre. Lactate dehydrogenase B (LDHB) controls autophagy in cancer.. 5th Meeting of the International Society for Proton Dynamics in Cancer (Bratislava, du 08/10/2014 au 11/10/2014).
2014
Brisson, Lucie ; Copetti, Tamara ; Sboarina, Martina ; Dethier, Coralie ; Sonveaux, Pierre. Lactate dehydrogenase B (LDHB) promotes autophagy-dependent tumor cell proliferation.. BACR annual meeting (Ghent,, 01/02/2014).
2014
Sonveaux, Pierre. Lactate metabolism regulates autophagy in cancer. Cell death in Cancer – 2nd edition (La Baule, France, du 14/05/2014 au 17/05/2014).
2014
Payen, Valéry ; Porporato, Paolo ; De Saedeleer, Christophe ; Préat, Véronique ; Feron, Olivier ; Sonveaux, Pierre. Lactate stimulates angiogenesis, prevents skeletal muscle atrophy and accelerates wound healing. 4th annual meeting of the ISPDC (Munich, Germany, du 10/10/2013 au 12/10/2013). In: Frontiers in Pharmacology, (2014). doi:10.3389/conf.fphar.2014.61.00033.
2014
Perez Escuredo, Jhudit ; Dadhich, Rajesh Kumar ; Dhup, Suveera ; Brisson, Lucie ; Van Hee, Vincent F ; Sonveaux, Pierre. Lactate triggers c-Myc expression and activity in normoxic tumor cells.. BACR annual meeting (Ghent,, 01/02/2014).
2014
Perez Escuredo, Jhudit ; Dadhich, Rajesh Kumar ; Dhup, Suveera ; Van Hee, Vincent F ; Brisson, Lucie ; Porporato, Paolo ; Sonveaux, Pierre. Lactate triggers glutamine uptake through c-Myc activation in oxidative cancer cells.. Annual meeting of the International Society for Tumor Metabolism (ISCaM) (Smolenice, Slovakia, du 08/10/2014 au 11/10/2014).
2014
Vanhoutte, Laetitia ; Esfahani, Hrag ; Feron, Olivier ; Balligand, Jean-Luc ; Gallez, Bernard ; Moniotte, Stéphane. Left ventricular systolic function assessment in a mouse model of cardiac hypertrophy using an 11.7T MRI scanner and comparison with ex-vivo measurements. Printemps de la cardiologie 2014 [Groupe de Réflexion sur la Recherche Cardiovasculaire] ((France) Strasbourg, du 24/04/2014 au 25/04/2014).
2014
Draoui, Nihed ; Polet, Florence ; Pinto, Adan ; Drozak, Xavier ; Riant, Olivier ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: a shift towards reductive glutamine metabolism driven by the SIRT1/HIF2α axis . 1st ISCAM meeting - 5th ISPDC meeting: Cancer metabolism: mechanisms, consequences and therapeutic opportunities (Smolenice - Slovakia, du 08/10/2014 au 11/10/2014).
2014
Corbet, Cyril ; Draoui, Nihed ; Polet, Florence ; Pinto Fernandez, Adan ; Drozak, Xavier ; Riant, Olivier ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: a shift towards reductive glutamine metabolism driven by the SIRT1/HIF2α axis . 1st ISCAM meeting - 5th ISPDC meeting: Cancer metabolism: mechanisms, consequences and therapeutic opportunities (Smolenice - Slovakia, du 08/10/2014 au 11/10/2014).
2014
Corbet, Cyril ; Feron, Olivier. Metabolic adaptation of tumor cells under chronic acidosis: role of the SIRT1/HIF2alpha axis to drive reductive glutamine metabolism. Interuniversity Attraction Poles Meeting (ULB Campus Erasme - Brussels, 12/06/2014).
2014
Porporato, Paolo ; Payen, Valéry ; Sonveaux, Pierre. Mitochondria in cancer metastasis: license to drive. Metabolism & cancer (Nice, France, du 25/09/2014 au 26/09/2014).
2014
Catry, Emilie ; Pachikian, Barbara D. ; Neyrinck, Audrey M. ; Cani, Patrice D. ; Dessy, Chantal ; Delzenne, Nathalie M.. O36: La supplémentation en prébiotiques améliore la dysfonction endothéliale induite par la déficience nutritionnelle en acides gras polyinsaturés de type n-3. 12es Journées Francophones de Nutrition, JFN 2014 (Brussels, Belgium, du 10/12/2014 au 12/12/2014). In: Nutrition Clinique et Métabolisme, Vol. 28, no.suppl 1, p. S48 (December 2014). doi:10.1016/S0985-0562(14)70612-0.
2014
Danhier, Fabienne ; Danhier, Pierre ; De Saedeleer, Christophe ; Fruytier, Anne-Catherine ; Schleich, Nathalie ; des Rieux, Anne ; Sonveaux, Pierre ; Gallez, Bernard ; Préat, Véronique. Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors. Translational Nanomedicine ((France) Angers, du 27/08/2014 au 29/08/2014).
2014
Catry, Emilie ; Rath, Géraldine ; Pachikian, Barbara D. ; Neyrinck, Audrey M. ; Cani, Patrice D. ; Dessy, Chantal ; Delzenne, Nathalie M.. Prebiotics supplementation improves the endothelial dysfunction in n-3 PUFA-depleted ApoE-/- mice. Belgian nutrition society : Genes and nutrition, is personalised nutrition the next realistic step? (Brussels, 25/04/2014). In: Archives of Public Health, Vol. 72, no.suppl 1, p. O5 (6 juin 2014). doi:10.1186/2049-3258-72-S1-O5.
2014
Baselet, Bjorn ; Aerts, An ; Rombouts, Charlotte ; Sonveaux, Pierre ; Baatout, Sarah. Radiation-induced cardiovascular risks and the potential prophylactic effects of statins. Séminaire de l'école doctorale en sciences pharmaceutiques et biomédicales (Salle Couvreur, UCL, Bruxelles, 20/01/2014).
2014
Corbet, Cyril ; Draoui, Nihed ; Drozak, Xavier ; Riant, Olivier ; Feron, Olivier. Sirtuin 1 mediates acidosis-induced metabolic reprogramming of tumor cells. BACR (Belgian Association for Cancer Research) Annual Meeting (Ghent University, 01/02/2014).
2014
Draoui, Nihed ; Drozak, Xavier ; Riant, Olivier ; Feron, Olivier. Sirtuin 1 mediates acidosis-induced metabolic reprogramming of tumor cells. Immunity and inflammation in cancer - Annual meeting of Belgian Association for Cancer Research (Ghent Univeristy, 01/02/2014).
2014
Porporato, Paolo. Skin structure - Wound healing models. 2nd Workshop Marie-Curie NANODRUG Network (Bruxelles, Université catholique de Louvain, FARG, du 13/03/2014 au 14/03/2014).
2014
Porporato, Paolo. Targeting mitochondria and metastasis: recent advances and perspectives.. Targeting Mitochondria 5th congress, World Mitochondria Society (Berlin, du 30/10/2014 au 31/10/2014).
2014
Copetti, Tamara ; De Saedeleer, Christophe ; Vegran, Frédérique ; Verrax, Julien ; Kennedy, Kelly M ; Moon, Eui J ; Dhup, Suveera ; Danhier, Pierre ; Frérart, Françoise ; Gallez, Bernard ; Ribeiro, Anthony ; Michiels, Carine ; Dewhirst, Mark W ; Feron, Olivier ; Sonveaux, Pierre. Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced angiogenesis. 4th annual meeting of the ISPDC (Munich, Germany, du 10/10/2013 au 12/10/2013). In: Frontiers in Pharmacology, (2014). doi:10.3389/conf.fphar.2014.61.00015.
2014
Dhooghe, Barbara. Vardenafil promotes relocalization of F508del-CFTR in human and mouse airways. 37th ECFS Conference (Gothenburg, du 11/06/2014 au 14/06/2014). In: Journal of Cystic Fibrosis, Vol. 13, no.Suppl 2, p. S1 (2014).
2022
Zampieri, Luca. Targeting mitophagy to overcome chemoresistance in ovarian and brain cancers, prom. : Sonveaux, Pierre, 13/01/2022.
2022
Vander Linden, Catherine. Towards a more rational use of metabolism-targeting drugs as anticancer treatments, prom. : Feron, Olivier ; Corbet, Cyril, 07/02/2022.
2022
Dierge, Emeline. Towards therapeutic exploitation of tumor addiction to fatty acids under acidosis, prom. : Larondelle, Yvan ; Feron, Olivier, 07/01/2022.
2022
Pothen, Lucie. Vascular memory, from old concepts to a new model : sustained down-regulation of alpha-Smooth Muscle Actin induced by Angiotensin II , prom. : Balligand, Jean-Luc, 31/08/2022.
2020
Grasso, Debora. Common metabolic alterations in cancer chemoresistance and radioresistance, prom. : Sonveaux, Pierre ; Gregoire, Vincent, 09/01/2020.
2020
Thabault, Léopold. Interrogating the lactate dehydrogenase tetrameric interface using (stapled) peptides and short proteins : an original approach to protein inhibition, prom. : Frédérick, Raphaël ; Sonveaux, Pierre, 23/10/2020.
2020
Joris, Virginie. MiR-199a family members : new actors of cardiovascular functions in health and disease, prom. : Dessy, Chantal, 27/08/2020.
2020
Santiago de Jesus, João Pedro. TGF-β2 at the crossroads between tumor acidosis, lipid metabolism and epithelial-to-mesenchymal transition, prom. : Feron, Olivier ; Corbet, Cyril, 19/06/2020.
2020
Schoonjans, Céline. Tumor microenvironment involvement in the metabolic reprogramming induced by the PDK inhibitor dichloroacetate, prom. : Gallez, Bernard ; Feron, Olivier, 18/12/2020.
2019
Doix, Bastien. Anticancer photodynamic therapy from direct cytotoxic effects to immunogenic cell death induction, prom. : Feron, Olivier, 30/10/2019.
2019
Montiel, Virginie. Aquaporin 1 and the left ventricular remodeling, prom. : Balligand , Jean-Luc, 04/02/2019.
2019
Spillier, Quentin. Mechanistic study of PHGDH enzyme inhibition : towards the development of new anticancer drugs, prom. : Frédérick, Raphaël ; Feron, Olivier, 24/10/2019.
2019
André, Emilie. Modulation of murine adult cardiac progenitors differentiation through specific interventions on epigenetics, paracrine signaling & metabolism, prom. : Balligand, Jean-Luc, 18/11/2019.
2019
Dei Zotti, Flavia. Quantification and regulation of erythrocyte HbNO as an index of vascular NO using EPR spectroscopy, prom. : Balligand, Jean-Luc ; Lobysheva, Irina, 05/04/2019.
2018
Payen, Valéry. Tumor metastasis under metabolic control : characterization and potential therapeutic implications, prom. : Sonveaux, Pierre ; Porporato, Paolo E., 23/02/2018.
2018
Vanhoutte, Laetitia. Ultra high field MRI for the characterization of murine models of cardiovascular diseases, prom. : Feron, Olivier ; Moniotte, Stéphane, 05/02/2018.
2017
Drozak, Xavier. Design, synthesis and biological evaluation of new glutaminase inhibitors, prom. : Riant, Olivier ; Feron, Olivier, 15/06/2017.
2017
Van Hee, Vincent. Functional characterization and imaging of oxidative lactate metabolism in cancer, prom. : Sonveaux, Pierre, 06/03/2017.
2017
Sboarina, Martina. Metabolic regulation of cancer cell proliferation and resistance to temozolomide chemotherapy, prom. : Lefranc , Florence ; Sonveaux, Pierre, 31/03/2017.
2017
Baselet, Bjorn. Molecular characterization of endothelial cell response in the context of radiation-induced atherosclerosis, prom. : Sonveaux, Pierre ; Aerts, An, 30/08/2017.
2016
Polet, Florence. Leukemia cells on diet : metabolic plasticity and new therapeutic strategies, prom. : Feron, Olivier, 20/06/2016.
2014
Draoui, Nihed. Development of inhibitors of lactate transport as an anticancer strategy : chemical synthesis, in vitro functional screening and in vivo therapeutic validation, prom. : Feron, Olivier ; Riant, Olivier, 29/01/2014.
2014
Grandjean, Marie. Optimization and exploitation of the serological proteome analysis to identify autoantibodies as biomarkers of colorectal cancer, prom. : Feron, Olivier, 07/01/2014.
2014
Hammond, Joanna. The cardiac myocyte beta-3 adrenoceptor and cardiac remodelling, prom. : Balligand, Jean-Luc, 10/06/2014.
2022
Sonveaux, Pierre ; Blackman, Marine ; Bedin, Marie ; Rondeau, Justin ; De Miranda Capeloa, Tania Isabel ; Kienlen-Campard, Pascal ; Van de Velde, Justine. Stem cells with brain tropism. .
2021
Sonveaux, Pierre ; De Miranda Capeloa, Tania Isabel. Molecular signature for assessing the responsiveness of cancer to mitochondria-targeted antioxidants. .
2021
Sonveaux, Pierre ; Thabault, Léopold ; Liberelle, Maxime ; Frédérick, Raphaël. Polypeptide inhibitors of lactate dehydrogenase activity for use in cancer therapy. Déposé. .
2019
Frédérick, Raphaël ; Thabault, Léopold ; Brisson, Lucie ; Copetti, Tamara ; Sonveaux, Pierre. Lactate dehydrogenase inhibitor polypeptides for use in treatment of cancer. .
2018
Sonveaux, Pierre ; Labar, Daniel ; Van Hee, Vincent F ; Dehon, Gwenaël ; Frédérick, Raphaël. [18F]-labelled lactate derivative as PET radiotracer. Numéro de priorité ; Déposé (09/09/2016) ; Publié (31/12/2018). EU.
2015
Sonveaux, Pierre ; Payen, Valéry ; Vazeille, Thibaut ; Niebes, Paul ; Porporato, Paolo. Composition antimétastatique comprenant au moins un composé de type flavonol. Numéro de priorité ; Déposé (10/11/2014) ; Publié (01/01/9999). .
2015
Draoui, Nihed ; Feron, Olivier ; Riant, Olivier ; Sonveaux, Pierre ; Schicke, Olivier ; Fernandes, Antony E. ; Kilonda, Amuri ; Vanherck, Jean-Christophe ; Marchand, Arnaud. Novel (anticancer) compounds (targeting metabolism). Numéro de priorité ; Déposé (06/06/2014) ; Publié (01/01/9999). .
2015
Feron, Olivier ; Dupont, Pierre ; Boidot, Romain ; Branders, Samuel ; Helleputte, Thibault. Signature of cycling hypoxia and use thereof for the prognosis of cancer. Numéro de priorité ; Déposé (01/08/2014) ; Publié (01/08/2015). .
2014
Corbet, Cyril ; Toillon, Robert-Alain ; Aubert, Léo ; Guilbert, Matthieu ; Le Bourhis, Xuefen. Combined use of a trka inhibitor and an epha2 inhibitor for using in the treatment of solid cancers, and method for the prognosis of survival of a patient who has a solid cancer. .
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