The three research axes - Statistics,  Biostatistics and Actuarial Sciences - are not pursued one independently from another. Research at the ISBA is based on a common methodological foundation, and the fields of application benefit from each other.

Members of the Institute actively collaborate with scientists from other disciplines on important research investigations. Within the LIDAM, the ISBA continues to develop its interdisciplinary research stronger than ever before: the Institute has initiated research projects with other UCLouvain units such as econometrics, finance, demography, psychometrics, epidemiology, sample surveys, technometrics, spatial statistics, bioinformatics and machine learning.

Moreover, the ISBA maintains a transfer of expertise outside the academic world via several collaborations with the pharmaceutical, financial, insurance or public sector.